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J Clin Microbiol ; 48(6): 2275-7, 2010 Jun.
Article in English | MEDLINE | ID: mdl-20392918

ABSTRACT

This study assessed an erythromycin-clindamycin (ERY-CC) broth test for inducible CC resistance in beta-hemolytic streptococci. One hundred one isolates of groups A, B, C, F, and G were tested by the CLSI broth microdilution method. Combinations of 1 and 0.25 microg/ml or 0.5 and 0.25 microg/ml of ERY and CC, respectively, detected all inducible isolates.


Subject(s)
Anti-Bacterial Agents/pharmacology , Clindamycin/pharmacology , Drug Resistance, Bacterial , Erythromycin/pharmacology , Streptococcus/drug effects , Hemolysin Proteins/metabolism , Humans , Microbial Sensitivity Tests/methods , Streptococcus/physiology , Transcriptional Activation
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