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1.
Oper Dent ; 44(3): 322-330, 2019.
Article in English | MEDLINE | ID: mdl-30444695

ABSTRACT

OBJECTIVE: To examine how exposure to accelerated artificial aging (AAA) stimuli (ultraviolet [UV] light) affects the color stability of a composite resin following surface sealant (SS) application. METHODS AND MATERIALS: A total of 30 cylindrical composite resin (Esthet-X) discs were prepared using Teflon-coated rings. The treatment groups, defined by different SS (Seal-N-Sine, PermaSeal, OptiGuard, Biscover LV, and DuraFinish) use, were divided into five groups of six discs each. The discs were subjected to baseline color measurements followed by measurements after surface sealant application (specular included component [SCI] and specular excluded component [SCE]) using a spectrophotometer. Three measurements (SCI and SCE) were performed for a total of 18 readings (test surface) per specimen group. All specimens were then exposed to a UV light source for a total of 382 hours. Color readings of the specimens were again recorded for each group. Quantitative color measurements were executed using Commission Internationale de l'Eclairage L*a*b* calculations. RESULTS: Baseline color measurements of the composite resin discs, following the AAA exposure protocol, revealed no significant differences. A comparison of the composite resin discs before and after SS application (without UV light exposure) showed statistically significant differences using both SCI and SCE measurement criteria. Although significant differences were encountered between the ΔL*, Δa*, Δb*, and ΔE parameters, all specimens (groups) were within the clinically acceptable range (1.0<ΔE≤ 3.3). Again, statistically significant differences were noted (ΔL*, Δa*, Δb*, and ΔE parameters) for all specimen groups receiving SS application, utilizing both SCI and SCE measurements, following exposure to UV light. All groups were within the clinically acceptable range (1.0<ΔE≤ 3.3), except the Durafinish group. The Durafinish SS group experienced significantly greater (p<0.001) overall color change (SCI and SCE) following UV light exposure. An intergroup comparison following UV exposure revealed that the Permaseal, OptiGuard, and Seal-n-Shine SS groups displayed the least amount of color change statistically but not necessarily always perceptibly significant, while the Durafinish group exhibited the greatest color change statistically and perceptibly. CONCLUSIONS: The color stability of a composite resin, including the addition of most SSs, was not affected perceptibly by UV light exposure.


Subject(s)
Composite Resins , Ultraviolet Rays , Color , Dental Materials , Materials Testing , Surface Properties
2.
J Fish Biol ; 91(2): 545-557, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28653326

ABSTRACT

This study tests for interspecific evidence of Heincke's law among hagfishes and advances the field of research on body size and depth of occurrence in fishes by including a phylogenetic correction and by examining depth in four ways: maximum depth, minimum depth, mean depth of recorded specimens and the average of maximum and minimum depths of occurrence. Results yield no evidence for Heincke's law in hagfishes, no phylogenetic signal for the depth at which species occur, but moderate to weak phylogenetic signal for body size, suggesting that phylogeny may play a role in determining body size in this group.


Subject(s)
Ecosystem , Hagfishes/classification , Phylogeny , Animals , Behavior, Animal , Body Size , Hagfishes/anatomy & histology
3.
Oper Dent ; 40(6): 653-61, 2015.
Article in English | MEDLINE | ID: mdl-26237636

ABSTRACT

OBJECTIVES: To determine microleakage of posterior Class I and II restorations using the SonicFill composite resin system. METHODS AND MATERIALS: Eighty previously extracted third molars were randomly assigned to four preparation/restoration groups (n=20): Group A: Class I preparations restored with SonicFill system/bulk fill; Group B: Class II preparations restored with SonicFill system/bulk fill; Group C: Class I preparations restored with Herculite Ultra composite resin/incremental technique; and Group D: Class II preparations restored with Herculite Ultra composite resin/incremental technique. Class I preparations were approximately 3.0 mm in width buccolingually and 3.0 mm in depth. Class II preparations were approximately 3.0 mm in width buccolingually, 1.5 mm in axial depth, and 4.0 mm in gingival depth. In all groups, the enamel and dentin surfaces were conditioned with Kerr 37.5% phosphoric acid, followed by application of Optibond Solo Plus adhesive system. Following restoration, the specimens were thermocycled, immersed in methylene blue dye, and embedded in acrylic resin. Specimen blocks were sectioned in the mesiodistal direction, with marginal dye penetration (microleakage) examined using a 20× binocular microscope. Class I and II restoration microleakage was scored separately using a 0-3 ordinal ranking system. Statistical analyses were conducted using nonparametric testing at the p < 0.05 level of significance. RESULTS: Significantly less microleakage was associated with both Class I restorative groups (A and C), SonicFill bulk fill and Herculite Ultra incremental fill, compared to the Class II restorative groups (B and D), SonicFill/bulk fill and Herculite Ultra/incremental fill. CONCLUSIONS: According to the results of this study, the materials (SonicFill vs Herculite Ultra), C-factors, and insertion techniques (bulk vs incremental) did not appear to be significant influences with regard to marginal microleakage; however, the type of preparation cavity (Class I vs Class II) and the subsequent bonding surface (enamel vs dentin [cementum]) proved to be significant factors.


Subject(s)
Composite Resins , Dental Leakage , Dental Restoration, Permanent/methods , Composite Resins/chemistry , Dental Caries/therapy , Dental Cavity Preparation/methods , Dental Enamel , Dentin , Humans , Random Allocation
4.
J Hist Behav Sci ; 50(3): 302-20, 2014.
Article in English | MEDLINE | ID: mdl-24911622

ABSTRACT

This paper examines one aspect of early twentieth century debates over the meaning of scientific methodology and epistemology within the social sciences: the tendency of sociologists to invoke "laboratory" as a multivalent concept and in reference to diverse institutions and sites of exploration. The aspiration to designate or create laboratories as spaces of sociological knowledge production was broadly unifying in early American sociology (1890-1930), even though there was no general agreement about what "laboratory" meant, nor any explicit acknowledgment of that lack of consensus. The persistence of laboratory talk in sociology over decades reflects the power of "laboratory" as a productively ambiguous, legitimizing ideal for sociologists aspiring to make their discipline rigorously scientific.


Subject(s)
Research Design/trends , Sociology/history , Vocabulary , History, 19th Century , History, 20th Century , History, 21st Century , Humans , United States
5.
Int J Sports Med ; 35(1): 83-6, 2014 Jan.
Article in English | MEDLINE | ID: mdl-23771828

ABSTRACT

Our goal was to present current data on the incidence of clavicle injuries presenting for urgent evaluation and to report the sports activities associated with injury. Using the National Electronic Injury Surveillance System (NEISS) database, the number of clavicle fractures presenting to a representative sample of U.S. hospitals was retrospectively calculated and weighted estimates used to extrapolate this data to the U.S. population. Incidence estimates were obtained using validated analyses and U.S. census data, with sports injuries being noted and fractures stratified by sport. A total of 9 428 fractures of the clavicle were reported, representing 357,155 injuries in the U.S. population over 5 years. The estimated incidence of clavicle fractures in the U.S. presenting for emergency care is 24.4 fractures per 100,000 person-years (95% confidence intervals (CI), 22.8-26.1). The peak incidence was highest between ages 10-19 years. Men were nearly 3 times as likely to sustain a clavicle fracture. Sports were a factor in 45% of all clavicle fractures. In sports-related injuries, 16% of fractures occurred from bicycling, followed by football (12%) and soccer (6%). In summary, injuries from bicycling were the most common cause of clavicle fracture, followed by contact sports. Male gender and younger age are risk factors for clavicle fractures.


Subject(s)
Athletic Injuries/epidemiology , Clavicle/injuries , Fractures, Bone/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Cross-Sectional Studies , Databases, Factual , Female , Fractures, Bone/etiology , Humans , Incidence , Infant , Male , Middle Aged , Population Surveillance , Retrospective Studies , United States/epidemiology , Young Adult
6.
Mucosal Immunol ; 6(2): 224-34, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23235744

ABSTRACT

A growing body of evidence suggests that non-hematopoietic stromal cells of the intestine have multiple roles in immune responses and inflammation at this mucosal site. Despite this, many still consider gut stromal cells as passive structural entities, with past research focused heavily on their roles in fibrosis, tumor progression, and wound healing, rather than their contributions to immune function. In this review, we discuss our current knowledge of stromal cells in intestinal immunity, highlighting the many immunological axes in which stromal cells have a functional role. We also consider emerging data that broaden the potential scope of their contribution to immunity in the gut and argue that these so-called "non-immune" cells are reclassified in light of their diverse contributions to intestinal innate immunity and the maintenance of mucosal homeostasis.


Subject(s)
Homeostasis/immunology , Immunity, Mucosal , Intestinal Mucosa/immunology , Stromal Cells/immunology , Animals , B-Lymphocytes/immunology , Cell Differentiation , Granulocytes/immunology , Humans , Intestinal Mucosa/metabolism , Lymphoid Tissue/immunology , Myeloid Cells/cytology , Stromal Cells/metabolism , T-Lymphocytes/immunology
7.
Asian-Australas J Anim Sci ; 26(1): 97-107, 2013 Jan.
Article in English | MEDLINE | ID: mdl-25049711

ABSTRACT

The aim of this study was to establish relationships between chemical and physical parameters of wheat with performance and digestibilities of feed components in broiler chickens fed on wheat-based diets. Ninety-four wheat samples were selected for inclusion in four bird trials. Birds were housed in individual wire metabolism cages from 7 to 28 d and offered water and feed ad libitum. Dry matter intake (DMI), liveweight gain (LWG) and gain:feed were measured weekly. A balance collection was carried out from 14 to 21 d for determination of apparent metabolizable energy (AME), ME:gain, dry matter retention, oil and neutral detergent fibre (NDF) digestibility. At 28 d the birds were humanely killed, the contents of the jejunum removed for determination of in vivo viscosity and the contents of the ileum removed for determination of ileal dry matter, starch and protein digestibility. When wheat parameters were correlated with bird performance data, it was found that specific weight was not significantly (p>0.05) related to bird performance. Bird DMI, LWG and gain:feed were best correlated (p<0.05) with the rate of starch digestion, although the coefficients of correlation (r) were still low (0.246 to 0.523). A negative relationship (p<0.01) between AME and total (r = -0.432) and soluble (r = -0.304) non starch polysaccharide (NSP) was observed in this study. Thousand grain weight (TG) was positively correlated with DMI (r = 0.299), LWG (r = 0.343) and gain:feed (r = 0.371). When establishing multiple regression relationships, correlation coefficients greater than 0.8 were achieved for DMI, LWG, gain:feed and ileal crude protein digestibility. However, the economics involved in determining the parameters involved in the regressions make the process impractical.

8.
Asian-Australas J Anim Sci ; 26(3): 378-85, 2013 Mar.
Article in English | MEDLINE | ID: mdl-25049800

ABSTRACT

The aim of this study was to examine the effect of variety and growing conditions of wheat on broiler performance and nutrient digestibility. One hundred and sixty-four wheat samples, collected from a wide range of different sources, locations, varieties and years, were analyzed for a range of chemical and physical parameters. Chemical and physical parameters measured included specific weight, thousand grain weight (TG), in vitro viscosity, gross energy, N, NDF, starch, total and soluble non-starch polysaccharides (NSP), lysine, threonine, amylose, hardness, rate of starch digestion and protein profiles. Ninety-four of the wheat samples were selected for inclusion in four bird trials. Birds were housed in individual wire metabolizm cages from 7 to 28 d and offered water and feed ad libitum. Dry matter intake (DMI), live weight gain (LWG) and gain:feed were determined weekly. A balance collection was carried out from 14 to 21 d for determination of apparent metabolizable energy (AME), ME:gain, DM retention, oil and NDF digestibility. At 28 d the birds were sacrificed, the contents of the jejunum removed for determination of in vivo viscosity and the contents of the ileum removed for determination of ileal DM, starch and protein digestibility. The wheat samples used in the study had wide-ranging chemical and physical parameters, leading to bird DMI, LWG, gain:feed, ME:GE, AME content and ileal starch and protein digestibility being significantly (p<0.05) affected by wheat sample. A high level of N fertilizer application to the English and NI wheat samples tended to benefit bird performance, with increases of up to 3.4, 7.2 and 3.8% in DMI, LWG and gain:feed, respectively. Fungicide application also appeared to have a positive effect on bird performance, with fungicide treated (+F) wheat increasing bird DMI, LWG and gain:feed by 6.6, 9.3 and 2.7%, over the non-fungicide treated (-F) wheats. An increase (p<0.1) of 9.3% in gain:feed was also observed at the low seed rate of 40 compared to 640 seeds/m(2). It was concluded that the type of wheat sample and environmental growing conditions significantly affects bird performance when fed wheat-based diets.

9.
J Hist Behav Sci ; 46(2): 165-88, 2010.
Article in English | MEDLINE | ID: mdl-20419789

ABSTRACT

This article examines the critical responses to Talcott Parsons' first major work, The Structure of Social Action (1937), and his two subsequent books, Toward a General Theory of Action and The Social System (both 1951). Because Parsons' work was the subject of such virulent debate, we cannot fully understand Parsons' impact on the discipline of sociology without understanding the source and nature of those early criticisms. I trace the responses to Parsons, first through book reviews and private letters and then in the more substantial statements of C. Wright Mills, George Homans, and Alvin Gouldner, from the largely positive but superficial reception of Structure to the polemics that followed Parsons' 1951 works. In the late 1930s and 1940s, Parsons' reputation grew steadily but there remained no careful reception of Structure, fostering resentment toward Parsons in some quarters while precluding a sophisticated understanding of his work. After 1951, a few critics capitalized on that tension, writing sweeping rejections of Parsons' work that spoke to a much broader audience of sociologists. That dynamic, coupled with Parsons' own indifference toward his harshest critics, produced a situation in which many sociologists simply chose not to read Parsons in the 1950s and 1960s, reinforcing a caricature and distorting perceptions of Parsons' place in mid-twentieth-century American sociology.


Subject(s)
Models, Theoretical , Sociology/history , Dissent and Disputes , History, 20th Century , Humans , Philosophy/history , Research/history , United States
10.
Br Poult Sci ; 50(1): 103-22, 2009 Jan.
Article in English | MEDLINE | ID: mdl-19234935

ABSTRACT

1. The aims of this study were to investigate the potential of near infrared reflectance spectroscopy (NIRS) to predict the chemical and physical characteristics of wheat and also to predict the nutritive value of wheat for broiler chickens. 2. A total of 164 wheat samples, collected from a wide range of different sources (England, Northern Ireland and Canada), varieties and years, were used in this study. 3. Chemical and physical parameters measured included specific weight, thousand grain weight, in vitro viscosity, gross energy, nitrogen, neutral detergent fibre (NDF), starch, total and soluble non-starch polysaccharides (NSP), lysine, threonine, amylose, hardness, rate of starch digestion and protein profiles. 4. A total of 94 wheat samples were selected for inclusion in three bird trials and included at 650 g/kg in a typical UK starter/grower diet. Birds were housed in individual wire metabolism cages from 7 to 28 d and offered water and food ad libitum. Dry matter intake (DMI), live weight gain (LWG) and gain:feed ratio were measured weekly. A balance collection was carried out from d 14 to 21 for determination of apparent metabolisable energy (AME), ME:gain and dry matter retention. At 28 d the birds were humanely killed, the contents of the jejunum removed for determination of in vivo viscosity and the contents of the ileum removed for determination of ileal dry matter, starch and protein digestibility. 5. The wheat samples were scanned as whole and milled wheat, both dried and undried and NIRS calibrations, first excluding and then including the Canadian wheat samples, were developed. 6. NIRS calibrations for milled wheat samples may be useful for determining specific weight (R(cv)(2) = 0.75, for milled wheat dried), nitrogen (R(cv)(2) = 0.983 for milled and dried) and rate of starch digestion (R(cv)(2) = 0.791 for milled, dried and undried). 7. NIRS calibrations for whole wheat samples (undried) may be useful for determining wheat nutritive value, with good predictions for live weight gain (R(cv)(2) = 0.817) and feed conversion efficiency (R(cv)(2) = 0.825). 8. Inclusion of the Canadian wheat samples in the NIRS analysis provided additional robust calibrations for gross energy (R(cv)(2) = 0.86, dried and milled) and starch content (R(cv)(2) = 0.79, undried and milled). 9. This study shows that NIR is a useful tool in the accurate and rapid determination of wheat chemical parameters and nutritive value and could be extremely beneficial to both the poultry and wheat industry. 10. Further extension of the dataset would be recommended to further validate these findings.


Subject(s)
Animal Feed/analysis , Chickens/growth & development , Spectroscopy, Near-Infrared/veterinary , Triticum/chemistry , Animal Nutritional Physiological Phenomena , Animals , Body Weight , Eating , Feces/chemistry , Male , Nutritive Value , Random Allocation
11.
Br Poult Sci ; 49(4): 463-74, 2008 Jul.
Article in English | MEDLINE | ID: mdl-18704793

ABSTRACT

1. A study of the relationship between specific weight (SW) and nutritive value of wheat in diets offered to broilers up to 4 weeks of age was carried out using 10 varieties of wheat grown at three different locations; this gave rise to a range of specific weights from 59 to 76 kg/hl. 2. Because five varieties contained the 1B1R translocation and 5 did not, this allowed the effects of 1B1R on the performance of birds given high concentrations of dietary wheat to be further investigated. 3. The diets, which contained wheat at 744 g/kg with casein (142 g/kg) as the sole protein supplement, were heat-treated and pelleted. They were fed ad libitum to male, Ross broiler chicks from 7 to 28 d, in individual cages in a controlled environment room. 4. A 7 d excreta collection was made from 14 to 21 d for determination of apparent metabolisable energy (AME) content and wheat AME was calculated from the diet values. A separate determination of true metabolisable energy (TME) was undertaken using the method of McNab and Blair (British Poultry Science, 29: 697-707, 1988). 5. Wheat samples were analysed for proximate constituents, starch, total and soluble non-starch polysaccharides (NSP), amino acid content and gross energy and specific weight, thousand grain weight and in vitro viscosity were recorded. They were also subjected to near infrared reflectance spectroscopy (NIRS) with a view to establishing relationships with chemical constituents and performance parameters. 6. At 28 d the birds were humanely killed and in vivo viscosity was determined on the jejunal digesta supernatant. 7. There was quite a narrow range of crude protein content (N x 5.83) across the 30 wheat samples, the means for the three locations (Crossnacreevy, Downpatrick and Limavady, respectively) being 112, 121 and 122 g/kg. Starch contents of individual samples ranged from 604 to 679 g/kg, total NSP from 92.1 to 122.6 g/kg, soluble NSP from 17.6 to 32.6 g/kg and in vitro viscosity from 10.6 to 26.3 cps. 8. There were no significant varietal effects for dry matter intake (DMI), live weight gain (LWG) or gain:feed ratio. Apparent metabolisability of energy (ME:GE) for the diets ranged from 0.738 (Hussar) to 0.778 (Harrier) the effect being significant (P < 0.05) and there was a significant (P < 0.001) relationship (r(2) = 0.46) between ME:GE and gain:feed ratios. Calculated wheat AME for individual varieties ranged from 14.1 to 15.0 MJ/kg DM (P > 0.05). TME values ranged from 16.3 to 16.6 MJ/kg DM (NS). 9. In vivo viscosity ranged from 12.3 (Ritmo) to 23.7 cps (Hussar), the varietal effects being significant (P < 0.001). Viscosity was significantly higher for the 1B1R varieties than for the non-1B1R (22.7 vs 16.3 cps) but there were no significant effects on mean DM intake, LWG, gain:feed, ME:GE, calculated wheat AME, ME:gain (MJ AME per kg gain) or TME. 10. Wheat AME was negatively correlated (P < 0.05) with total NSP (slope -0.035) but was significantly affected by variety, constants ranging from 16.74 to 17.79. For wheat TME there were significant variety*total NSP interactions with slopes ranging from 0.29 to -0.07. There was no significant relationship between wheat AME and soluble NSP and there were significant variety*soluble NSP interactions for TME with slopes ranging from 0.09 to -0.14. 11. Despite the relatively wide range of in vitro viscosity there was no significant correlation of either calculated wheat AME or wheat TME with in vitro viscosity. For TME there were significant variety*viscosity interactions with slopes ranging from 0.21 to -0.13 (P < 0.001). There was also no significant correlation between soluble NSP and in vivo viscosity. 12. AME values for the NIRS calibration set varied from 13.7 to 15.6 MJ/kg and averaged 14.6 MJ/kg, whereas for the validation set, the values ranged from 14.0 to 16.1 MJ/kg with the mean value being 14.7 MJ/kg. The best correlation coefficient (r(2)) of 0.90 was obtained when the calibration sample set was subjected to SMLR using the second-order derivatised data. However, moving to validation, the outcome was extremely poor with 1-VR values being 0.12 and 0.09, respectively, for the external validation and an internal validation subset. 13. In summary, none of the production characteristics showed a good correlation with specific weight. Using the linear estimates for wheat AME and TME the effect of a 10 kg/hl change in SW equates to a 3 or 1.4% change, respectively. The estimate for AME is likely to be a worst-case value due to the high inclusion level of wheat. The range of calculated wheat AME (approximately 1 MJ) across the 30 wheat samples is similar to that seen in previous studies for wheat grown in Northern Ireland and much lower than in some other studies. 14. None of the other parameters examined gave any better relationship with nutritive value (assessed as AME or TME) than SW. This is a disappointing outcome, particularly in view of some previous studies which suggested that in vitro viscosity provides a good prediction of nutritive value.


Subject(s)
Chickens/physiology , Triticum/genetics , Triticum/physiology , Animal Feed , Animal Nutritional Physiological Phenomena , Animals , Diet/veterinary , Energy Metabolism , Feces/chemistry , Male , Nutritive Value
12.
Br Poult Sci ; 49(2): 202-12, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18409095

ABSTRACT

1. The objectives of this experiment were to investigate the effects of different xylanases, alone or in combination with different organic acid and oligosaccharide sources, on bird performance, gut microflora and ileal histology. 2. Birds were given a diet based on a commercial formulation, which was split into 8 batches. Batch 1 contained the antibiotic growth promoter Avilamycin and acted as the positive control. To batch 2 the enzyme Allzyme PT was added and to batch 3 Allzyme PT was added with the organic acid and oligosaccharide mixture Avimos. To batch 4, Allzyme PT was added with the oligosaccharide mixture Biomos. To batch 5, yeast extract 2012 was added with the organic acid mixture Gustor and the enzyme xylanase XP20. To batch 6, yeast extract 2012 and feed acidifier Gustor were added as before, with the enzyme Avizyme 1300. Batches 7 and 8 both acted as negative experimental controls, with no added growth promoters. 3. A total of 64 birds were housed in individual wire cages in each of three consecutive experimental replicates (24 birds/treatment). Birds were fed ad libitum from 7 to 28 d and a 7-d excreta collection was carried out to determine apparent metabolisable energy (AME) content. 4. At 28 d, the birds were killed and viscosity of jejunal digesta supernatant and gizzard weight were determined. Samples were taken from the crop, ileum and caecum and analysed for viable presumptive lactic acid bacteria and coliforms. The overall microbial flora was determined using denaturing gradient gel electrophoresis of 16S ribosomal DNA followed by DNA sequence analysis in order to assign amplicons to a bacterial species. Ileal sections were also collected for histological analysis. 5. Total live weight gain (12%) and gain:feed (9%) were significantly improved for all diets containing additives, compared to the negative control diets. All diets containing xylanases gave significantly lower in vivo viscosity values than the positive and negative controls. Diet treatment significantly affected viable coliform numbers in the ileum and also viable lactobacilli in the ileum and caecum. A substantial proportion of the bacteria present in the GI tract (40%) belong to unknown species. No effects of diet treatment on histological measurements were observed in this study. 6. All the additive combinations studied were at least as effective as the antibiotic growth promoter and the results for Allzyme PT suggest that xylanase alone is as effective as any of the combinations studied.


Subject(s)
Animal Feed , Chickens/physiology , Food Additives/administration & dosage , Ileum/anatomy & histology , Intestines/microbiology , Animals , Chickens/anatomy & histology , Colony Count, Microbial , Endo-1,4-beta Xylanases/administration & dosage , Energy Intake , Energy Metabolism , Enterobacteriaceae , Lactobacillus , Oligosaccharides/administration & dosage , Weight Gain
13.
Res Vet Sci ; 84(3): 387-94, 2008 Jun.
Article in English | MEDLINE | ID: mdl-17765939

ABSTRACT

The aim of the experiment was to study the effect of dietary organic acids, fumaric and sorbic, on nitrogen corrected apparent metabolisable energy (AME(N)), metabolisability of nutrients, endogenous losses and performance on young broiler chickens. A total of 56 male Ross broilers were used in a growing experiment from 14 to 30d age. Seven experimental wheat-based (655g/kg) diets were formulated. The control diet did not contain organic acids. The other six diets were produced with the addition of fumaric or sorbic acids, replacing 0.5% , 1.0% or 1.5% of the wheat. The organic acid supplemented diets contained higher levels of AME(N) compared to the control diet. Overall, birds offered organic acids had lower feed intake. Dietary organic acids did not significantly affect weight gain or feed efficiency, however, birds offered supplemented diets had lower numbers of Lactic acid bacteria and Coliforms in the ileum and caeca. Birds offered organic acids had lower levels of endogenous losses compared to control fed birds. There was a negative relationship between AME(N) of the diets and excreted endogenous losses, measured as sialic acid. It can be concluded that the decrease in secretions from the gastrointestinal tract in the presence of fumaric and sorbic acids may be a mechanism involved in the mode of action of dietary organic acids.


Subject(s)
Animal Feed , Chickens/growth & development , Food Additives/administration & dosage , Fumarates/administration & dosage , Sorbic Acid/administration & dosage , Animals , Dietary Proteins , Digestion/drug effects , Food Additives/pharmacology , Fumarates/pharmacology , Growth/drug effects , Sorbic Acid/pharmacology
14.
Int J Sports Med ; 28(7): 617-20, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17357966

ABSTRACT

Despite some anecdotal evidence, the racial differences in tendon injuries have received little attention in the literature. We sought to determine the effect of race on major tendon injuries. A search was performed according to the International Classification of Diseases, Ninth Revision, Clinical Modification code 727.65 (rupture of quadriceps tendon), 727.66 (rupture of patellar tendon), and 727.67 (rupture of Achilles tendon) using the U. S. Defense Medical Epidemiology Database (DMED). Multivariate poisson regression was used to estimate the rate of major tendon rupture per 1000 person-years, while controlling for differences in gender, service, rank, and age for each code. We computed rate ratios and 95% confidence intervals using whites as the referent category. The adjusted rate ratio for black service members when compared to white service members was 2.89 (95% CI 2.42, 3.44) for quadriceps tendon tears, 4.52 (95% CI 3.94, 5.19) for patellar tendon tears, and 3.58 (95% CI 3.31, 3.88) for Achilles tendon tears. There appears to be a significant relative predisposition toward lower-extremity major tendon rupture in black U. S. service members when compared to white service members. Investigation of the racial differences in risk factors is warranted.


Subject(s)
Achilles Tendon/injuries , Black or African American , Rupture/epidemiology , White People , Achilles Tendon/physiopathology , Adult , Female , Humans , Male , Military Personnel , United States/epidemiology
15.
Br Poult Sci ; 48(1): 49-54, 2007 Feb.
Article in English | MEDLINE | ID: mdl-17364540

ABSTRACT

1. The objectives of this experiment were to compare the effects of different yeast products, with different nucleotide contents and inclusion rates, on broiler performance and to compare the effects to those observed with an antibiotic growth promoter. 2. Two experiments were carried out over two time replicates, one in individual wire cages and one in group pens. 3. Birds were given a diet based on a commercial formulation, which was split into 7 batches. One batch (C) contained no growth promoter and acted as a negative control, another (AV) contained the antibiotic growth promoter Avilomycin (5 g/tonne) and acted as the positive control. The other batches contained yeast extract 2012 at 100 g/tonne (Y21), yeast extract 2012 at 500 g/tonne (Y25), standard yeast 18 at 100 g/tonne (Y81), standard yeast 18 enriched in nucleotides at 100 g/tonne (Y8N1) and standard yeast 18 enriched in nucleotides at 500 g/tonne (Y8N5). 4. In the penned experiment, 280 Cobb broiler chicks (40 birds/treatment) were randomised to diet and pen position on day of hatch. Birds were fed ad libitum until slaughter at 28 d. Bird performance was monitored during the experimental period. 5. In the individual cage experiment, 63 Cobb broiler chicks (9 birds/treatment) were taken from the pens at 7 d of age and randomised to diet and cage position. Birds were fed ad libitum from d 7 to d 28. A 7-d excreta collection was carried out to determine apparent metabolisable energy (AME) content and nutrient digestibility between d 14 and d 21. Bird intake and weight were monitored weekly during the experimental period. At 28 d the birds were killed and viscosity of jejunal digesta supernatant was determined. 6. In the penned experiment, diet had no significant effect on dry matter intake (DMI), live weight gain (LWG) or gain:feed values during any individual week of the experiment or for the entire experimental period. In the caged experiment, DMI was numerically highest for birds fed Y25 diet over the entire experimental period, however, this only reached significance in the second week. LWG, gain:feed, viscosity of jejunal contents and gizzard weight were not significantly affected by dietary treatment. 7. Diet AV had a significantly higher AME content than diets Y25, Y81, Y8N1 or Y8N5. Also, oil and neutral detergent fibre (NDF) digestibility coefficients were significantly affected by diet treatment.


Subject(s)
Animal Feed , Anti-Bacterial Agents/pharmacology , Chickens/growth & development , Dietary Supplements , Yeasts , Animals , Chickens/metabolism , Eating , Random Allocation , Weight Gain
16.
J Bone Joint Surg Br ; 88(11): 1419-24, 2006 Nov.
Article in English | MEDLINE | ID: mdl-17075083

ABSTRACT

The floating shoulder is defined as ipsilateral fractures of the midshaft of the clavicle and the neck of the glenoid. This rare injury can be difficult to manage without a thorough understanding of the complex anatomy of the shoulder girdle. Surgical intervention needs to be considered for all of these injuries. While acceptable results can be expected with non-operative management of minimally-displaced fractures, displacement at one or both sites is best managed with surgical reduction and fixation.


Subject(s)
Clavicle/injuries , Shoulder Fractures/therapy , Shoulder Joint/surgery , Biomechanical Phenomena , Clavicle/surgery , Fracture Healing/physiology , Humans , Orthopedic Procedures/methods , Shoulder Fractures/physiopathology , Shoulder Fractures/surgery , Shoulder Joint/anatomy & histology , Shoulder Joint/physiopathology , Treatment Outcome
17.
J Bone Joint Surg Br ; 88(8): 1102-4, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16877615

ABSTRACT

The aim of this study was to determine the effectiveness of antibiotic-impregnated implants in the prevention of bone infection. We used a model of contaminated fracture in goats to evaluate four treatment groups: no treatment, hand-made tobramycin-impregnated polymethylmethacrylate beads, commercially-available tobramycin-impregnated calcium sulphate pellets and commercially-available tobramycin-impregnated polymethylmethacrylate beads. Three weeks after intraosseous inoculation with streptomycin-resistant Staphylococcus aureus tissue cultures showed no evidence of infection in any of the antibiotic-treated groups. All of the cultures were positive in the untreated group. These results show that effective local antibiotic delivery can be obtained with both commercially-available products and with hand-made polymethylmethacrylate beads. The calcium sulphate pellets have the advantage of being bioabsorbable, thereby obviating the need for a second procedure to remove them.


Subject(s)
Anti-Bacterial Agents/administration & dosage , Bone Diseases, Infectious/prevention & control , Microspheres , Polymethyl Methacrylate , Tobramycin/administration & dosage , Animals , Bone Diseases, Infectious/complications , Calcium Sulfate/administration & dosage , Colony Count, Microbial/methods , Disease Models, Animal , Drug Implants/administration & dosage , Fractures, Bone/complications , Goats , Male , Staphylococcus aureus/isolation & purification , Treatment Outcome
19.
Surg Endosc ; 17(9): 1498, 2003 Sep.
Article in English | MEDLINE | ID: mdl-12802656

ABSTRACT

Perforation of the gallbladder with resultant spillage of gallstones is not an uncommon occurrence. Spillage is reported to occur in 6% to 40% of laparoscopic cholecystectomies. Although not generally considered a significant problem, retained gallstones may cause serious complications years after the operation, with a clinical presentation that often is confusing. We report two cases of unusual complications from spilled gallstones. The first patient presented with clinical and radiologic findings of acute appendicitis 8 years after the laparoscopic cholecystectomy. The second patient presented with spontaneous erosion of spilled gallstones through the back 2 years and 9 months after the laparoscopic cholecystectomy. The literature is reviewed, and the management of spilled gallstones is discussed briefly. Although the complication rate is low, every effort should be made to retrieve spilled gallstones, and the event should be recorded in detail in the operative record. Obligatory conversion to an open procedure is not necessary.


Subject(s)
Abscess/etiology , Appendicitis/diagnosis , Cholecystectomy, Laparoscopic , Gallbladder/injuries , Gallstones , Intraoperative Complications , Postoperative Complications/etiology , Abscess/surgery , Acute Disease , Adult , Aged , Appendectomy , Back , Debridement , Diagnosis, Differential , Female , Humans , Pelvis , Postoperative Complications/diagnosis , Postoperative Complications/surgery , Tomography, X-Ray Computed
20.
Burns ; 29(2): 159-62, 2003 Mar.
Article in English | MEDLINE | ID: mdl-12615463

ABSTRACT

When faced with large numbers of burn patients and limited resources such as in war or disaster, oral fluids may be used as an alternative to intravenous resuscitation. Vomiting during the first 48 h can limit the usefulness of this method; yet its incidence has not been documented. This study aimed to identify those patients at risk of vomiting following burn injury and who therefore might be suitable for oral resuscitation. A retrospective review of case notes from burn patients between 1990 and 2001 was undertaken. Burns requiring intravenous resuscitation (>10% total body surface area (TBSA) in children, >15% TBSA in adults) were included (n=110). Documentation of vomiting during the first 48 h following burn injury to an extent that prevented commencement of feeding was regarded as significant. Patients that vomited were significantly older (28.3 years compared with 18.5 years, P=0.03), and had sustained significantly larger burns (29.8% compared with 22.9%, P=0.047). Administration of opiates and anti-emetics was similar in both groups and not significant. Although the number of patients in this study excludes a logistic regression analysis, it would seem reasonable to attempt oral resuscitation in patients under 25 years of age and with burns up to 25% TBSA given limited resources.


Subject(s)
Burns/complications , Fluid Therapy/methods , Vomiting/etiology , Adolescent , Adult , Aged , Aged, 80 and over , Body Surface Area , Burns/therapy , Child , Disasters , Drinking , Emergency Medicine/methods , Female , Humans , Male , Middle Aged , Retrospective Studies , Risk Factors , Vomiting/therapy
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