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IEEE Trans Med Imaging ; 17(6): 900-9, 1998 Dec.
Article in English | MEDLINE | ID: mdl-10048847

ABSTRACT

This paper is concerned with the potential for the detection and location of an artery containing a partial blockage by exploiting the space-time properties of the shear wave field in the surrounding elastic soft tissue. As a demonstration of feasibility, an array of piezoelectric film vibration sensors is placed on the free surface of a urethane mold that contains a surgical tube. Inside the surgical tube is a nylon constriction that inhibits the water flowing through the tube. A turbulent field develops in and downstream from the blockage, creating a randomly fluctuating pressure on the inner wall of the tube. This force produces shear and compressional wave energy in the urethane. After the array is used to sample the dominant shear wave space-time energy field at low frequencies, a nearfield (i.e., focused) beamforming process then images the energy distribution in the three-dimensional solid. Experiments and numerical simulations are included to demonstrate the potential of this noninvasive procedure for the early identification of vascular blockages-the typical precursor of serious arterial disease in the human heart.


Subject(s)
Coronary Disease/diagnosis , Coronary Vessels/physiopathology , Models, Anatomic , Models, Cardiovascular , Phonocardiography/methods , Amplifiers, Electronic , Biophysical Phenomena , Biophysics , Blood Flow Velocity , Color , Coronary Disease/physiopathology , Feasibility Studies , Humans , Mathematics , Phonocardiography/instrumentation , Phonocardiography/statistics & numerical data , Time Factors , Urethane
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