Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Language
Publication year range
1.
Mini Rev Med Chem ; 7(5): 451-60, 2007 May.
Article in English | MEDLINE | ID: mdl-17504180

ABSTRACT

To develop the newer pharmaceuticals and to spur the strong growth, being a general property of 'handedness', chirality plays a major role. The Easson-Stedman principle shows the differences in the biological activity between enantiomers resulted from selective reactivity of one enantiomer with its receptor. It helps to improve the pharmacokinetic properties and to remove undesirable side effects by virtue of the unique activity of enantiomers. Racemic switching and marketing drug combinations are used as tools for drug life-cycle management and to redevelop racemic mixtures as single enantiomers.


Subject(s)
Chemistry, Pharmaceutical/methods , Drug Design , Pharmaceutical Preparations/chemistry , Molecular Conformation , Stereoisomerism
2.
SELECTION OF CITATIONS
SEARCH DETAIL
...