1.
Clin Exp Dermatol
; 43(7): 860-862, 2018 10.
Article
in English
| MEDLINE
| ID: mdl-29896851
Subject(s)
Genetic Diseases, X-Linked/pathology , Microphthalmos/pathology , Skin Abnormalities/pathology , Chromosome Deletion , Dermoscopy/methods , Diagnosis, Differential , Female , Genetic Diseases, X-Linked/diagnosis , Genetic Diseases, X-Linked/genetics , Humans , Infant, Newborn , Microphthalmos/diagnosis , Microphthalmos/genetics , Skin/pathology , Skin Abnormalities/diagnosis , Skin Abnormalities/genetics
2.
Br J Dermatol
; 152(6): 1332-4, 2005 Jun.
Article
in English
| MEDLINE
| ID: mdl-15949003
ABSTRACT
Epidermolysis bullosa (EB) pruriginosa is a distinctive clinical subtype of dystrophic EB. We report a patient with dominant dystrophic EB pruriginosa, who had an excellent response to systemic thalidomide treatment. The mechanism of action of thalidomide in the management of pruriginous disorders is not yet completely understood. Most recent studies point towards an immunomodulatory action of thalidomide that may suppress excessive production of tumour necrosis factor-alpha and may downregulate certain cell surface adhesion molecules involved in leucocyte migration.
