Unveiling the multifaceted world of anthocyanins: Biosynthesis pathway, natural sources, extraction methods, copigmentation, encapsulation techniques, and future food applications.

Numerous datasets regarding anthocyanins have been noted elsewhere. These previous studies emphasized that all processes must be carried out meticulously from the source used to obtain anthocyanins to their inclusion in relevant applications. However, today, full standardization has not yet been achieved for these processes. For this, presenting the latest developments regarding anthocyanins under one roof would be a useful approach to guide the scientific literature. The current review was designed to serve the stated points. In this context, their biosynthesis pathway was elaborated. Superior potential of fruits and certain by-products in obtaining anthocyanins was revealed compared to their other counterparts. Health-promoting benefits of anthocyanins were detailed. Also, the situation of innovative techniques (ultrasound-assisted extraction, subcritical water extraction, pulse electrical field extraction, and so on) in the anthocyanin extraction was explained. The stability issues, which is one of the most important problems limiting the use of anthocyanins in applications were discussed. The role of copigmentation and various encapsulation techniques in solving these stability problems was summarized. This critical review is a map that provides detailed information about the processes from obtaining anthocyanins, which stand out with their functional properties, to their incorporation into various systems.

Psychometric Evaluation of the Healing After Gender-Based Violence Scale: An Instrument for Cross-Sectional and Longitudinal Assessment of Recovery Progress for Women-Identifying Survivors.

Purpose: The Healing after Gender-based Violence Scale (GBV-Heal) was developed to measure the holistic recovery processes of woman-identifying survivors of gender-based violence (GBV). The GBV-Heal asks survivors to evaluate a series of statements based on perceptions of one's lowest point and how they currently feel. These scale response options create lowest point, current feelings, and difference scores to evaluate the healing outcome cross-sectionally. This manuscript aims to evaluate the psychometric properties of the GBV-Heal to understand its usefulness for research and practice. Method: Instrument evaluation consisted of two phases analyzing online survey data from two GBV survivor samples recruited from online health research portals in the United States. In Phase One (N = 236), we conducted factor analyses and evaluated convergent/discriminant validity using depression, anxiety, posttraumatic stress, posttraumatic growth, and wellbeing measures. In Phase Two (N = 47), we evaluated GBV-Heal response consistency via test-retest within two weeks. Results: Results showed that the scale's final model included 4 components with 18 items, explaining 61.2% and 65% of the overall scale variances for "at my lowest point" and "my current feelings," respectively. The GBV-Heal difference score showed a weak positive correlation with wellbeing and posttraumatic growth scores and a weak negative correlation with depression, anxiety, and PTSD scores. Test-retest revealed Pearson r correlations of 0.82, 0.82, and 0.69 for the lowest point, current feelings, and difference scores respectively. Conclusion: These findings substantiate the reliability and validity of our instrument as an outcome measure that can be used both cross-sectionally and longitudinally with survivors of GBV.

The Turkish Validity and Reliability Study of the Observable Social Cognition -A Rating Scale for Patients with Schizophrenia. / Sizofreni Hastalarinda Gözlenebilir Toplumsal Bilisi Degerlendirme Ölçegi'nin Türkçe Geçerlik ve Güvenirlik Çalismasi.

OBJECTIVE: The Observable Social Cognition-A Rating Scale (OSCARS) is an eight-item, interview-based psychometric tool that was developed by Healey et al. (2015) for evaluating social cognition with respect to the theory of mind, emotion perception, and attributional style in schizophrenia. The aim of this study is to determine the validity and reliability of the Turkish version of the scale. METHOD: The study was conducted with 50 patients with schizophrenia and schizoaffective disorder and 50 relatives of these patients using the OSCARS, the Face Emotion Discrimination/Identification Test (FEDT/FEIT), the Positive and Negative Symptoms Scale (PANSS), the Global Assessment of Functioning (GAF) and the Dokuz Eylül Theory of Mind Index (DEZIKO). The validity of the OSCARS was assessed by exploratory factor analysis and concurrent validity analysis, the reliability was demonstrated by the internal consistency coefficient, item-total item correlation, and test-retest comparisons. RESULTS: The Cronbach's alpha coefficient of the OSCARS-TR was 0.83. Explanatory factor analysis yielded a 2-factor structure explaining 64.2% of the total variance of the scale. The total score of the OSCARSTR correlated significantly with the DEZIKO (r=-0.49), the GAF (r=- 0.50), the PANSS (r=0.54) and the FEDT (r=-0.29) total scores but not with the FEIT scores. The total scores of the OSCARS-TR completed by the patients and by the relatives of the patients correlated with statistical significance (r=0.93). The test-retest reliability coefficient of OSCARS-TR was 0.95. CONCLUSION: The results demonstrated the validity and the reliability of the OSCARS-TR. The scale can be easily implemented on an interview basis as an appropriate tool for evaluating social cognition.

The Turkish Validity and Reliability Study of the Observable Social Cognition -A Rating Scale for Patients with Schizophrenia. / Sizofreni Hastalarinda Gözlenebilir Toplumsal Bilisi Degerlendirme Ölçegi'nin Türkçe Geçerlik ve Güvenirlik Çalismasi.

OBJECTIVE: The Observable Social Cognition-A Rating Scale (OSCARS) is an eight-item, interview-based psychometric tool that was developed by Healey et al. (2015) for evaluating social cognition with respect to the theory of mind, emotion perception, and attributional style in schizophrenia. The aim of this study is to determine the validity and reliability of the Turkish version of the scale. METHOD: The study was conducted with 50 patients with schizophrenia and schizoaffective disorder and 50 relatives of these patients using the OSCARS, the Face Emotion Discrimination/Identification Test (FEDT/FEIT), the Positive and Negative Symptoms Scale (PANSS), the Global Assessment of Functioning (GAF) and the Dokuz Eylül Theory of Mind Index (DEZIKO). The validity of the OSCARS was assessed by exploratory factor analysis and concurrent validity analysis, the reliability was demonstrated by the internal consistency coefficient, item-total item correlation, and test-retest comparisons. RESULTS: The Cronbach's alpha coefficient of the OSCARS-TR was 0.83. Explanatory factor analysis yielded a 2-factor structure explaining 64.2% of the total variance of the scale. The total score of the OSCARSTR correlated significantly with the DEZIKO (r=-0.49), the GAF (r=- 0.50), the PANSS (r=0.54) and the FEDT (r=-0.29) total scores but not with the FEIT scores. The total scores of the OSCARS-TR completed by the patients and by the relatives of the patients correlated with statistical significance (r=0.93). The test-retest reliability coefficient of OSCARS-TR was 0.95. CONCLUSION: The results demonstrated the validity and the reliability of the OSCARS-TR. The scale can be easily implemented on an interview basis as an appropriate tool for evaluating social cognition.

Assessing the efficacy and feasibility of providing metacognitive training for patients with schizophrenia by mental health nurses: A randomized controlled trial.

AIM: To evaluate the efficacy of metacognitive group training in reducing psychotic symptoms and improving cognitive insight and functions in people with schizophrenia. DESIGN: Randomized controlled trial. It was carried out between July 2019 -February 2020. METHODS: Fifty-six patients with schizophrenia were enrolled and randomly assigned to either a control group (N = 29) or a metacognitive training group (N = 27). Blinded assessments were made at baseline, 1-week post-treatment and at follow-up 3 months after treatment. The primary outcome measure was psychotic symptoms based on the Psychotic Symptom Rating Scales (PSYRATS). Secondary outcomes were assessed by the Beck Cognitive Insight Scale (BCIS), the Personal and Social Performance (PSP) scale and the World Health Organization Disability Assessment Schedule (WHODAS). RESULTS: Completion at follow-up was high (92.86%). The intention-to-treat analyses demonstrated that patients in the metacognitive training group had significantly greater improvements of the Psychotic Symptom Rating Scales delusion score and total score and the Personal and Social Performance Scale, after 3 months, compared with the control group. The effect size was medium to large. The intention-to-treat analyses also demonstrated that patients in the metacognitive training group had significantly greater reductions of the Psychotic Symptom Rating Scales hallucination score and Beck Cognitive Insight Scale self-certainty score post-treatment, compared with the control group. The effect size was medium to large. CONCLUSION: The metacognitive training administered by psychiatric and mental health nurses was effective in ameliorating delusions and social functioning over time and it immediately reduced hallucinations post-treatment. IMPACT: Metacognitive training for treating psychosis in patients with schizophrenia is efficacious and administration is clinically feasible in the Portuguese context. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov ID NCT03891186.

A retrospective examination of the content of violence in headlines of news related to individuals with mental disorders.

BACKGROUND: Headlines are usually read first. Since headlines are designed to be remarkable and memorable in terms of form and meaning, their impact on the positive or negative attitudes of the society towards individuals with mental illness may be greater than the news texts. AIMS: This study aimed to retrospectively examine and analyze the content of violence headlines related to people with mental disorders. METHOD: The study was designed to examine headlines retrospectively. Six-hundred-ten headlines on the websites of four nationally published newspapers in Turkey were reviewed. Headlines mentioned people with mental disorders and violent events. The News Headline Review Form was used to evaluate the headlines. Descriptive statistics, the chi-square test and logistic regression analysis were used in data analysis. RESULTS: It was determined that violent events in headlines were mostly associated with homicidal behaviors (72%; n = 439), self-harming behaviors (20.2%; n = 123) and exploitation by others (7.8%; n = 40), respectively. The most common actions in headlines were, within the homicidal behaviors, "murder" (30.4%; n = 186); within the self-harming behaviors, "commit suicide" (13.6%; n = 83) and within the exploitation-by-others category, "being murdered" (4.4%; n = 27). People with mental disorders were in an active position in three fourths of the headlines on violence/aggression (77.3%; n = 471). CONCLUSION: Headlines have the effect of normalizing the relationship between violence and mental disorders, which already exists in society. Portraying violence as a typical part of a mental disorder could create social perceptions that it is the nature of these individuals to exhibit violent behavior.

Turkish newspaper articles mentioning people with mental illness: A retrospective study.

BACKGROUND: Because a great majority of the public knows about mental disorders primarily through printed or visual media, the attitudes exhibited in mass media might be predictive in stigmatizing individuals with mental disorders. AIM: The aim of this study was to retrospectively assess the articles in Turkish newspapers that mention individuals with mental disorders. METHOD: This study was designed to retrospectively investigate and analyze newspaper content in Turkey; the newspapers' circulation information was collected by examining the websites of the four newspapers with above 1% of the total circulation. The News Evaluation Form was used to evaluate a sampling of articles that met the inclusion criteria of having appeared in the lifestyle and agenda pages of newspapers, and of using neutral or negative labeling keywords about psychiatric patients. RESULTS: Almost all the articles reviewed were negative toward individuals with mental disorders. Three quarters of the reports were forensic, among which two thirds of the individuals with mental disorders were criminalized, and one third were victims of crime. In approximately half of the news reports, most images were related to the news and were not protected. Although not all the articles contain stigmatizing elements directed toward people with mental disorders, two thirds of the subjects' images in the news were found to have stigmatizing elements. CONCLUSION: Media has an impact on attitudes toward people with mental disorders mostly negatively along with individual experiences and peer interactions.

Initial psychometric evaluation of the physical health attitude scale and a survey of mental health nurses.

WHAT IS KNOWN ON THE SUBJECT?: A clear association exists between serious mental illness (SMI) and poor physical health. Individuals with SMI have markedly higher risks for mortality and morbidity. Mental health nurses play an important role in enhancing service users' mental and physical well-being. The attitudes of mental health nurses towards physical health care have been explored in the western part of the world. However, cross-country differences should be determined to reveal the importance of this global issue. WHAT THE PAPER ADDS TO EXISTING KNOWLEDGE?: This study adds new data to the literature on the Physical Health Attitude Scale's (PHASe) validity and nurses' attitudes when working in acute mental health services in different cultures. Nurses in acute mental health wards mostly focus on the basic physiological indicators of patients' existing physical health problems, so health promotion practices such as sexual health and eye/dental examinations are neglected for individuals with SMI. Nurses' higher level of confidence about their delivery of physical health care is due to their familiarity with basic nursing practices (e.g. monitoring blood pressure and checking blood glucose levels). Differences that exist between countries in relation to smoking habits are probably due to different regulations. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: To improve patients' physical healthcare outcomes, nurses should be provided with additional training and supervision to strengthen their skills and confidence. Nurses' perceived need for additional training reflects the importance of physical health care in mental health settings, in which training could substantially improve patient outcomes. Authors believe that standard protocols must be established in acute psychiatric care to eliminate obstacles to holistic patient care. Training needs of mental health nurses on health promotion practices should be considered by administrators of mental health settings. Abstract Introduction Nurses play an important role in improving the physical health of individuals with serious mental illnesses. The literature on the attitudes of mental health nurses towards physical health care provides a small amount of data. Assessing trends in nurses' attitudes through suitable surveys is important to ensure holistic care. Aim/Question This study sought to examine the Turkish version of the Physical Health Attitude Scale's (PHASe) validity and reliability and to survey Turkish mental health nurses' attitudes towards physical health care. Method The sample consisted of 174 nurses working in acute psychiatric wards. Firstly, the psychometric properties of the scale were analysed using factor analysis and measures of internal consistency and reliability. Then, the survey results of the attitudes of mental health nurses towards the physical health of patients with serious mental illnesses were determined using the Physical Health Attitude Scale (PHASe). Results The translated PHASe functioned best as a 24-item version and 4-factor solution that explains 51.3% of the variance. The internal consistency value was 0.83. The respondents' attitudes were generally positive about their role. There was less agreement for the involvement of nurses in practices of health promotion, such as sexual health, eye and/or dental examinations. The nurses surveyed also tended to use smoking for therapeutic purposes. Implications for practice Mental health nurses' knowledge and attitudes should be enhanced by additional training in the ways of meeting patients' biopsychosocial needs. Obstacles to physical health care can be removed by implementing standard protocols nationwide.

Physical Healthcare of People with Serious Mental Illness: A Cross-Sectional Study of Nurses' Involvement, Views, and Current Practices.

Background: Based on the poor physical health and unhealthy lifestyle behaviors, people with serious mental illness (SMI) have a high risk for long-term disorders such as diabetes, cardiovascular and respiratory diseases. Aims: This study examined nurses' current practices and views regarding the physical health of people with SMI. Methods: Cross-sectional study was conducted among nurses working in acute wards in large mental health hospital in Istanbul, Turkey. Convenience sample of 184 nurses agreed to participate in the study. Data collection was based on the self-reported responses. Descriptive statistics and comparison tests were used to describe the sample's characteristics and identify associations amongst the participants' characteristics. Findings: The results showed that nurses considered the patients' physical health important, particularly female nurses. Monitoring blood pressure, assessing physical health status at admission, and helping self-care needs were common practices. Believing in the importance of physical health was correlated with high knowledge and self-confidence levels in delivery of physical healthcare. Discussion: These findings are useful for implementing integrated nursing care in acute psychiatric care and improving patients' mental and physical well-being.

The Effect of Psychosocial Skills Training and Metacognitive Training on Social and Cognitive Functioning in Schizophrenia.

INTRODUCTION: The aim of this study is to investigate the effects of Psychosocial Skills Training (PSST) and Metacognitive Training (MCT) programs on general psychopathology, cognitive functioning, and social functioning in patients with schizophrenia. METHODS: Twenty patients with schizophrenia who were treated at the Kocaeli University Psychiatry Department outpatient clinic between January and June 2016, accepted to participate in the study and met inclusion criteria were included in this study. Patients were randomized as two groups of 10 people. The management of each group was carried out by a trainer and a co-trainer. The Positive and Negative Symptom Scale (PANSS) and Clinical Global Impression Scale-Severity (CGI-S) to assess psychopathology, the General Assessment of Functioning (GAF) and the Quality of Life Scale in Schizophrenia (QoLS) to assess social functioning, the Cognitive Assessment Interview (CAI) to assess cognitive functioning were used by the clinicians blinding to groups in the first two weeks before and after the intervention. After the training, first and last test scale scores were compared. RESULTS: All patients who participated in the study completed the study (male: 13, female: 7). There was no significant difference in age, gender, marital status, years of education, duration of illness, the age of onset, and the number of hospitalizations in comparison of individual and clinical characteristics of the groups (p>0.05). When the scores were compared of the groups before and after the intervention, there was a significant difference concerning psychopathology, social and cognitive functioning in both groups (p<0.05). There were no significant differences between the groups in terms of effect size. CONCLUSION: The study showed that both programs aiming to improve psychopathology and functioning in the treatment of schizophrenia have positive results. Improvement in cognitive functioning should also be tested by neurocognitive tests in the large-scale studies with control groups.