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1.
Int J Gynaecol Obstet ; 78(2): 127-30, 2002 Aug.
Article in English | MEDLINE | ID: mdl-12175713

ABSTRACT

OBJECTIVES: Our goal was to identify risk factors associated with umbilical cord prolapse and to review the perinatal outcome of cases of cord prolapse. METHODS: During the study years 77 cases were identified retrospectively. Associations between cord prolapse and potential risk factors were evaluated by means of the odds ratio. RESULTS: Of the 77 fetuses with umbilical cord prolapse 9.1% had a fetal weight of < 2500 gas compared with 9.4% for fetuses in control group (P > 0.05). The umbilical cord prolapse occurred in association with vertex presentation 66 times (85.7%), breech presentation nine times (11.7%) and transverse presentation two times (2.6%). The occurrence of breech presentation among the control cases was 2.6%, and that of transverse lie was 1.7% (P < 0.01). Case mothers were 1.6 times more likely to be multiparas compared with the control group (P < 0.01). The perinatal mortality rate was 39/1000. CONCLUSIONS: Our study showed that abnormal fetal presentation and multiparity are associated with an increased risk of umbilical cord prolapse. The association of risk of cord prolapse with low birth weight was statistically insignificant (P > 0.05). We suggest that the cesarean delivery decreased the risk of perinatal mortality among cases of cord prolapse.


Subject(s)
Pregnancy Outcome , Prolapse , Umbilical Cord/pathology , Adolescent , Adult , Female , Humans , Infant, Newborn , Infant, Very Low Birth Weight , Labor Presentation , Odds Ratio , Parity , Pregnancy , Retrospective Studies , Risk Factors
2.
Int J Clin Pharmacol Ther Toxicol ; 30(7): 230-2, 1992 Jul.
Article in English | MEDLINE | ID: mdl-1506126

ABSTRACT

Indomethacin is a potent tocolytic agent used in premature labor. The most observed adverse effect was the constriction of ductus arteriosus, causing persistent fetal circulation postnatally. Until recently, decrease in amniotic fluid during treatment with indomethacin has been shown partly by subjective methods. In comparison with posttreatment results, using "amniotic fluid index", transient decrease in amniotic fluid was determined semi-quantitatively.


Subject(s)
Indomethacin/adverse effects , Oligohydramnios/chemically induced , Tocolytic Agents/adverse effects , Female , Humans , Maternal-Fetal Exchange/physiology , Obstetric Labor, Premature/prevention & control , Pregnancy
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