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Transplant Proc ; 37(10): 4509-12, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16387156

ABSTRACT

BACKGROUND: Long-term survival after heart transplantation is a desirable although challenging goal. METHODS: We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years. RESULTS: We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy. CONCLUSIONS: Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.


Subject(s)
Heart Transplantation/statistics & numerical data , Survivors/statistics & numerical data , Adult , Cohort Studies , Female , Graft Rejection/epidemiology , Heart Transplantation/immunology , Heart Transplantation/mortality , Heart Transplantation/physiology , Humans , Immunosuppression Therapy , Male , Middle Aged , Retrospective Studies , Survival Analysis , Time Factors , Tissue Donors/statistics & numerical data
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