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Zh Mikrobiol Epidemiol Immunobiol ; (2): 49-54, 1986 Feb.
Article in Russian | MEDLINE | ID: mdl-3515812

ABSTRACT

In the trial of the trivalent subunit influenza vaccine Grippovac CE-AK observations on children aged 3-6 years were made. The preparation showed insignificant reactogenicity and moderate antigenic potency. The trial established that at the period of the epidemic rise of influenza B morbidity the vaccine showed, according to the data of the clinical diagnosis of influenza, insignificant effectiveness, its index of effectiveness (IE) being 1.08; according to the data of the serological diagnosis of influenza, only the A (H1N1) component of the vaccine was found to have IE equal to 1.58.


Subject(s)
Influenza A virus/immunology , Influenza B virus/immunology , Influenza Vaccines/immunology , Antibodies, Viral/analysis , Child , Child, Preschool , Clinical Trials as Topic , Humans , Immunization , Influenza Vaccines/adverse effects , Influenza, Human/prevention & control , Moscow , Seasons , Time Factors , Urban Population
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