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1.
Int J Clin Pract ; 75(5): e14032, 2021 May.
Article in English | MEDLINE | ID: mdl-33484197

ABSTRACT

AIM OF THE STUDY: The main objective of this prospective and observational study was to investigate the effect of the preoperative hospitalisation period on early postoperative cognitive dysfunction (POCD) development in patients undergoing total hip replacement surgery under regional anaesthesia. MATERIALS AND METHODS: Between November 2013 and September 2014, 64 patients were enrolled in the study. Mini Mental Test (MMT) scores were obtained on the initial admission day (MMT1), 24 hours prior to the surgery (MMT2) and 24 hours after the surgery (MMT3). The patients were divided into two groups according to the MMT scores: 'no cognitive dysfunction' (group 1) and 'cognitive dysfunction' (group 2). Differences between the groups were evaluated statistically. The statistical significance level was set as P < .05 in a 95% confidence interval. RESULTS: The POCD incidence rate was calculated as 43.8% in all patients. The preoperative hospitalisation duration was significantly longer in patients with POCD than in patients without POCD (P < .001). The factors that affected POCD development were found to be advanced age (P < .001), high American Society of Anesthesiologists scores (P = .004), the presence of comorbid disease (P = .025), durations of surgery (P = .018) and decreased postoperative haematocrit levels (P = .014). CONCLUSION: In this study, we observed that patients with early POCD had relatively longer preoperative hospitalisation periods than those in patients without POCD. We consider that prolonged preoperative hospitalisation may contribute to increased POCD incidence rates in patients with risk factors.


Subject(s)
Anesthesia, Conduction , Postoperative Cognitive Complications , Anesthesia, Conduction/adverse effects , Hospitalization , Humans , Neuropsychological Tests , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Prospective Studies
3.
Nutr Clin Pract ; 24(2): 274-80, 2009.
Article in English | MEDLINE | ID: mdl-19321901

ABSTRACT

BACKGROUND: Malnutrition in hospitalized patients is a significant problem. The purpose of this study was to compare 2 assessment tools-the Nutritional Risk Screening 2002 (NRS 2002) and subjective global assessment (SGA)-in predicting development of complications in patients undergoing orthopedic surgery. METHODS: Nutrition status was assessed by the SGA, and nutrition screening was performed using the NRS 2002 in 256 consecutively admitted patients scheduled for orthopedic surgery. Additional information recorded for all patients included age, gender, body mass index, and American Society of Anesthesiologists (ASA) physical status. Patient outcomes (postoperative complications), mortality rate, and length of hospital stay (LOS) were investigated. RESULTS: Malnourished or nutritionally at-risk patients were significantly older than nonmalnourished or not at-risk patients according to the SGA and NRS 2002. Also, ASA physical status was correlated with malnutrition or malnutrition risk. Malnourished and at-risk patients in both the SGA and NRS 2002 groups showed longer LOS and higher morbidity and mortality rates. Sensitivity was 50% with the SGA and 69% with the NRS 2002; specificity was 77% with the SGA and 80% with the NRS 2002. Agreement between 2 methods was 0.672. The odds ratio for the association between malnutrition or risk of malnutrition and the occurrence of complications was 3.5 (1.7-7.1) for the SGA and 4.1 (2.0-8.5) for NRS 2002. CONCLUSIONS: Age and ASA physical status are risk factors for malnutrition. In patients undergoing orthopedic surgery, NRS 2002 predicted development of complications better than the SGA. Malnutrition also increased length of hospital stay.


Subject(s)
Health Status , Malnutrition/diagnosis , Mass Screening , Nutrition Assessment , Orthopedic Procedures/methods , Postoperative Complications/epidemiology , Surveys and Questionnaires/standards , Age Factors , Aged , Female , Humans , Length of Stay , Male , Malnutrition/complications , Middle Aged , Nutritional Status , Odds Ratio , Orthopedic Procedures/mortality , Postoperative Complications/mortality , Predictive Value of Tests , Reproducibility of Results , Sensitivity and Specificity , Treatment Outcome
4.
Anesth Analg ; 107(6): 2068-72, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19020160

ABSTRACT

BACKGROUND: We evaluated in which anatomic layer (above the fascia [AF] or below the fascia [BF]) wound infusion of bupivacaine has the best effect on postoperative pain after abdominal hysterectomy. METHODS: Sixty-two ASA physical status I and II patients undergoing total abdominal hysterectomy and bilateral salpingo-oophorectomy were enrolled into this prospective randomized, double-blind study. A standard general anesthetic was administered. On completion of the operation, a multiorifice 20-gauge epidural catheter was placed above (group AF, n = 29) or below (group BF, n = 31) the superficial abdominal fascia and 0.25% bupivacaine was administered via a patient-controlled analgesia device, programmed to deliver 9.0 mL with a 60-min lockout interval for 24 h. During the first 6 h after surgery, rescue i.v. fentanyl (25 microg) was administered to achieve a visual analog scale score of <4 cm. Total bupivacaine consumption, total rescue fentanyl consumption, pain scores (with resting, coughing, and leg raising), and patient satisfaction scores were compared in both groups. RESULTS: Total bupivacaine consumption over 24 h was significantly lower in group AF rather than group BF (90 +/- 26 mL vs 104 +/- 28 mL, respectively, P < 0.05). The total fentanyl consumption during the first 6 h after surgery was 109 +/- 59 microg in group AF and 166 +/- 70 microg in group BF (P < 0.01). Pain scores were lower in group AF at rest and coughing for the first 5 h and for the first 12 h with leg raise (P < 0.05 for all measurements). Thirteen patients (68%) in group AF defined their satisfaction as excellent whereas six patients (32%) in group BF defined their satisfaction as excellent (P = 0.034). CONCLUSION: We conclude that bupivacaine wound infusion AF provides better postoperative analgesia compared with infusion BF in the first 12 h after abdominal hysterectomy.


Subject(s)
Anesthetics, Local/administration & dosage , Bupivacaine/administration & dosage , Hysterectomy , Pain, Postoperative/drug therapy , Adult , Double-Blind Method , Fascia , Female , Humans , Middle Aged
7.
J Anesth ; 20(4): 304-6, 2006.
Article in English | MEDLINE | ID: mdl-17072696

ABSTRACT

Forestier's disease, also called diffuse idiopathic skeletal hyperostosis (DISH), is a noninflammatory enthesopathy, ossifying the anterolateral spine and sparing the disc and joint space in elderly men, mostly at thoracic levels. Intubation difficulty and spinal cord injury are potential problems when managing the airway in DISH patients. We report a patient with Forestier's disease who was admitted for osteophyte resection. After taking a detailed history, we evaluated the airway carefully. Also, preparation for difficult intubation was done. After a rapid sequence induction, we performed mask ventilation and laryngoscopy without hyperextension of the neck, to prevent spinal cord injury. Although the worldwide standard for management of the airway in DISH patients is awake fiberoptic intubation, we chose conventional laryngoscopy because a fiberoptic bronchoscope was not available.


Subject(s)
Airway Obstruction/etiology , Hyperostosis, Diffuse Idiopathic Skeletal/complications , Intubation, Intratracheal/methods , Laryngoscopy/methods , Tracheal Stenosis/etiology , Aged , Airway Obstruction/therapy , Anesthesia, General , Anesthesia, Intravenous , Humans , Hyperostosis, Diffuse Idiopathic Skeletal/surgery , Intubation, Intratracheal/instrumentation , Male , Tracheal Stenosis/therapy
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