ABSTRACT
PURPOSE: To obtain simultaneous 24-hour contact lens voltage and systemic arterial blood pressure values with the Sensimed Triggerfish system and Holter monitoring device. METHODS: Ten primary open-angle glaucoma (POAG) and 8 pseudoexfoliation glaucoma (PXG) patients were included in the study. The Sensimed Triggerfish contact lens device was used to calculate the 24-hour IOP, and a Holter sphygmomanometer device was used for simultaneous 24-hour blood pressure measurements. We define the 8:00 am-11:00 pm period measurements as diurnal values and the other measurements as nocturnal values. RESULTS: The mean nocturnal systolic values (nocturnal SBP 120.5±3.4 for POAG and 122.8±5.3mmHg for PXG) and diastolic BP (nocturnal DBP 70.2±1.9 for POAG and 68.1±1.2mmHg for PXG) were lower than the diurnal (diurnal SBP 134.6±5.3 for POAG, 145.9±41.7mmHg for PXG, diurnal DBP 79.4±5.8 for POAG and 78.6±5.1mmHg for PXG) values, and these differences were statistically significant in both groups (P=0.001 in DBP in PXG and P<0.001 for other values). In addition, nocturnal CL voltage values (228.8±41.1 for POAG and 214.3±47.0mVEq for PXG) were higher than the diurnal values (55.8±77.2 for POAG and 145.9±41.7mVEq for PXG) in the POAG and PXG groups, and these were statistically significant as well (P<0.001 for all). In the POAG and PXG groups, CL voltage had a statistically significant negative correlation with systolic (respectively, r: -0.248, P=0.001 and r: -0.272, PË0.001) and diastolic (respectively, r: -0.115, P=0.036 and r: -0.160, P=0.028) BP values. CONCLUSION: We observed that CL voltage values rose during the nocturnal period, with a concomitant decrease in systolic and diastolic BP.
Subject(s)
Blood Pressure Monitoring, Ambulatory , Blood Pressure/physiology , Exfoliation Syndrome/physiopathology , Glaucoma, Open-Angle/physiopathology , Intraocular Pressure/physiology , Tonometry, Ocular , Aged , Blood Pressure Monitoring, Ambulatory/instrumentation , Blood Pressure Monitoring, Ambulatory/methods , Blood Pressure Monitors , Circadian Rhythm/physiology , Exfoliation Syndrome/diagnosis , Female , Glaucoma, Open-Angle/diagnosis , Humans , Male , Middle Aged , Time Factors , Tonometry, Ocular/instrumentation , Tonometry, Ocular/methodsABSTRACT
PURPOSE: Physical activity is associated with many health-related benefits. However, there is a shift towards inactive lifestyles around the world. Subclinical hypothyroidism (SCH) may have adverse effects similar to hypothyroidism. The presence of symptoms and reduced physical performance in SCH may contribute to an inactive lifestyle. Therefore, the present study aimed to compare physical activity levels (PALs) between women with subclinical hypothyroidism and healthy controls. METHODS: Thirty-two women with newly diagnosed SCH and 28 healthy women were enrolled in this cross-sectional study. Arterial stiffness was evaluated by pulse wave velocity (PWV). Neuromuscular symptoms were questioned. Participants wore a physical activity monitor (SenseWear® Armband) for 4 consecutive days. Handgrip and quadriceps muscle strength were assessed by dynamometer. Functional exercise capacity was assessed by 6-minute walk test (6MWT). RESULTS: There was no significant difference in sociodemographic variables between the groups. PWV was significantly higher in the SCH group (P = 0.006). Physical activity duration and number of steps were significantly lower in the SCH group (P < 0.05). There was significant difference in neuromuscular symptoms, handgrip and quadriceps muscle strength, and 6MWT distance between the groups (P < 0.05). CONCLUSIONS: This study demonstrates that women with SCH had lower PALs compared to healthy controls. Women with SCH should participate in exercise programs to increase physical activity and muscle strength to achieve adequate PALs.
Subject(s)
Activities of Daily Living , Exercise , Hypothyroidism/physiopathology , Muscle, Skeletal/physiopathology , Thyroid Hormones/blood , Adult , Case-Control Studies , Cross-Sectional Studies , Female , Follow-Up Studies , Humans , Hypothyroidism/blood , Prognosis , Pulse Wave AnalysisABSTRACT
Spontaneous pneumothorax that occurs in patients with no underlying lung disease is termed primary spontaneous pneumothorax (PSP). Recurrence of pneumothorax is usually seen without surgical procedures at any time. The aim of this study was to determine the recurrence time and rate of PSP after the first episode. A total of 82 PSP patients who had been treated in a thoracic surgery clinic between March 2011 and August 2012 were studied retrospectively. Video-assisted thoracoscopic surgery (VATS) was performed in 14 of 82 patients because of prolonged air leakage. These patients were excluded from the study to determine the recurrence period of PSP in our cases. Simple endotracheal intubation with low-volume high-frequency ventilation and three-port VATS technique were applied. Bullae or blebs were excised using an endoscopic linear stapler. Apical pleurectomy was performed in all of the patients. There were no cases in which VATS was converted to open thoracotomy. Recurrence of PSP was seen in 18 (26.47 %) of 68 patients. We found 26.47 % recurrence at the first 7 months, of which 94.4 % occurred at the first 6 months. About 77.77 % of these recurrences occurred at 3 months after discharge from hospital. Recurrence after the first episode of PSP is a common problem within the first 6 months. The thoracic surgeon should give knowledge about it to all patients. With the greater use of VATS for thoracic pathologies, it could be performed for the first period of pneumothorax in the future.
