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1.
Ann Plast Surg ; 91(3): 331-336, 2023 09 01.
Article in English, German | MEDLINE | ID: mdl-37347178

ABSTRACT

BACKGROUND: Seroma is a relatively common complication after breast reconstruction with tissue expanders. The main risk in the presence of seroma is development of periprosthetic infection, which can lead to implant loss. Our goals were to identify risk factors for seroma, and to describe our protocol for managing fluid accumulation. PATIENTS AND METHODS: An IRB approved breast reconstruction database was reviewed to identify patients who underwent tissue expander reconstruction. Patient characteristics, details of surgery, outcomes and treatment were recorded. RESULTS: Two hundred nineteen tissue expander reconstructions were performed in 138 patients. Twenty-eight reconstructions developed seroma (12.8%), and 75 were identified to have prolonged drains (34.2%). Seroma was more common in patients with lymph node surgery ( P = 0.043), delayed reconstruction ( P = 0.049), and prepectoral reconstruction ( P = 0.002). Seroma and/or prolonged drains were more commonly noted in patients with higher body mass index ( P = 0.044) and larger breast size ( P = 0.001). Aspiration was the most common intervention (85.7%), which was performed in the clinic utilizing the expander port site. There was no difference in infection or explantation rate between seroma and no-seroma patients ( P = 0.546 and 0.167), whereas patients with any fluid concern (seroma and/or prolonged drains) were more prone to developing infection and undergoing explantation ( P = 0.041 and P < 0.005). CONCLUSION: We recommend that prolonged drain placement longer than 3 weeks should be avoided, and patients should be screened for fluid accumulation after drain removal. Serial aspiration via expander port site and continuation of expansion provide a safe and effective method to manage seromas to avoid infection and expander loss.


Subject(s)
Breast Implants , Breast Neoplasms , Mammaplasty , Humans , Female , Tissue Expansion Devices/adverse effects , Retrospective Studies , Mammaplasty/adverse effects , Mammaplasty/methods , Drainage/adverse effects , Tissue Expansion/adverse effects , Tissue Expansion/methods , Seroma/epidemiology , Seroma/etiology , Seroma/therapy , Breast Neoplasms/complications , Breast Implants/adverse effects , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Postoperative Complications/surgery
2.
Ann Plast Surg ; 87(4): 396-401, 2021 10 01.
Article in English | MEDLINE | ID: mdl-34559710

ABSTRACT

BACKGROUND: Despite best practices, infection remains the most common complication after breast reconstruction with expanders and implants, ranging from 2% to 29%. Empiric broad-spectrum antibiotics are frequently used in nonsurgical treatment of implant-associated infections in an effort to salvage the reconstruction. Pitfalls of antibiotherapy include adverse events, vascular access site complications, and drug resistance. Our goals were to describe management of implant infections with broad-spectrum antibiotics, review treatment related adverse events, and report on outcomes of therapy. PATIENTS AND METHODS: A retrospective review was carried out to identify patients who were treated with intravenous (IV) antibiotics for periprosthetic infection. Patient characteristics, surgical details, and antibiotic therapy-related adverse events were collected. Eventual outcome related to expander/implant salvage was noted. RESULTS: A total of 101 patients (111 treatment episodes) were identified. Mean duration of antibiotic treatment was 18 days (range, 1-40 days). The most commonly used parenteral treatment was a combination of daptomycin with piperacillin-tazobactam (65%) or an alternative agent (16%). Fifty-nine percent of treatment episodes resulted in salvage of the expander or implant. Thirty-five percent treatment episodes were associated with 1 or more adverse events: diarrhea (12.6%), rash (10%), vaginal candidiasis (3.6%), agranulocytosis/neutropenic fever (3.6%), nausea (3.6%), urinary complaint (0.9%), myositis (0.9%), headache (0.9%), vascular line occlusion (1.8%), deep vein thrombosis (1.8%), and finger numbness (0.9%). No patients developed Clostridium difficile colitis. Five episodes (4%) needed discontinuation of antibiotics because of severe adverse events. The prosthesis was explanted in 3 of the cases of discontinued treatment. CONCLUSIONS: Our findings show favorable outcomes and well-tolerated adverse effects with broad-spectrum parenteral antibiotherapy for periprosthetic infection. However, every effort should be made to deescalate therapy by narrowing the spectrum or limiting the duration, to minimize adverse events and development of bacterial resistance. Treating surgeons need to carefully weigh benefits of therapy and be aware of potential complications that might necessitate discontinuation of treatment.


Subject(s)
Breast Implantation , Breast Implants , Prosthesis-Related Infections , Anti-Bacterial Agents/adverse effects , Breast Implantation/adverse effects , Breast Implants/adverse effects , Female , Humans , Prosthesis-Related Infections/drug therapy , Retrospective Studies
3.
J Plast Reconstr Aesthet Surg ; 74(3): 480-485, 2021 03.
Article in English | MEDLINE | ID: mdl-33069605

ABSTRACT

INTRODUCTION: Contralateral prophylactic mastectomy has the potential to decrease the occurrence of cancer and reduce psychological burden. However, it is known that complications after bilateral mastectomy are higher compared with unilateral mastectomy. Our goal was to evaluate outcomes of immediate breast reconstruction in patients undergoing bilateral mastectomy and to compare complication rates between therapeutic and prophylactic sides. PATIENTS AND METHODS: Electronic medical records of patients with unilateral breast cancer who underwent bilateral mastectomy and immediate reconstruction with expanders were reviewed. Postoperative complications were compared between therapeutic and prophylactic mastectomy sides. RESULTS: Sixty-two patients were analyzed. The overall complication rate after both stages was 23.9% on the therapeutic side and 16.5% on the prophylactic side. Infection was the most common complication on both sides. All infections on the prophylactic mastectomy side were successfully treated with intravenous (IV) antibiotics (salvage rate of 100%), whereas 35.7% of infected tissue expander/implants on the therapeutic mastectomy side were explanted despite treatment. CONCLUSION: Careful counselling of patients undergoing elective contralateral prophylactic mastectomy is essential as complications can develop in either breast after reconstruction.


Subject(s)
Anti-Bacterial Agents/administration & dosage , Mastectomy , Prophylactic Mastectomy , Prosthesis-Related Infections , Surgical Wound Infection , Unilateral Breast Neoplasms/surgery , Administration, Intravenous , Adult , Directive Counseling/methods , Electronic Health Records/statistics & numerical data , Female , Humans , Mastectomy/adverse effects , Mastectomy/methods , Middle Aged , Needs Assessment , Prophylactic Mastectomy/adverse effects , Prophylactic Mastectomy/methods , Prosthesis-Related Infections/epidemiology , Prosthesis-Related Infections/etiology , Prosthesis-Related Infections/therapy , Risk Assessment/methods , Surgical Wound Infection/epidemiology , Surgical Wound Infection/etiology , Surgical Wound Infection/therapy , Unilateral Breast Neoplasms/epidemiology , United States/epidemiology
4.
Aesthetic Plast Surg ; 44(6): 2075-2082, 2020 12.
Article in English | MEDLINE | ID: mdl-32840671

ABSTRACT

BACKGROUND: Periprosthetic infection remains the most common complication after implant-based breast reconstruction. Objectives of the study were to (1) describe our clinical approach and treatment protocol for managing patients with suspected periprosthetic infection, (2) identify the microorganisms causing periprosthetic infections at our institute, and (3) report on outcomes of implant salvage versus explantation. METHODS: A retrospective chart review of patients who were treated with parenteral antibiotics for periprosthetic infection was carried out. Patient characteristics, clinical and laboratory findings, outcomes, treatment modalities and complications were extracted from electronic medical records. Data were compared between patients whose implants were salvaged versus explanted. RESULTS: Fifty-nine patients with 67 tissue expander (TE)/implants underwent parenteral antibiotic treatment for suspected infection. Thirty-three (49%) of the TE/implants were salvaged. Mean follow-up was 14.3 months. The most commonly cultured organisms were P. aeruginosa followed by S. epidermidis. All suspected infections were treated with broad spectrum parenteral antibiotics with MRSA coverage. The most common combination was daptomycin 6 mg/kg combined with Zosyn 4.5 g. Explantations were significantly more common in patients with history of chemotherapy (p = 0.03), hypertension (p = 0.04) and those who underwent therapeutic mastectomy (p = 0.04). CONCLUSION: Risk factors for explantation due to postoperative periprosthetic infections following TE/implant-based breast reconstruction include chemotherapy, hypertension and therapeutic mastectomy. Prompt diagnosis and effective treatment of periprosthetic infection, particularly in these high-risk patients, are imperative to salvage the breast reconstruction. Gram-negative bacteria are increasingly found in breast implant infections and should be covered when employing empiric antibiotherapy. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Subject(s)
Breast Implantation , Breast Implants , Breast Neoplasms , Mammaplasty , Breast Implantation/adverse effects , Breast Implants/adverse effects , Breast Neoplasms/surgery , Follow-Up Studies , Humans , Mammaplasty/adverse effects , Mastectomy , Retrospective Studies , Tissue Expansion Devices/adverse effects , Treatment Outcome
5.
Ann Plast Surg ; 85(2S Suppl 2): S155-S160, 2020 08.
Article in English | MEDLINE | ID: mdl-32358230

ABSTRACT

BACKGROUND: A novel coronavirus disease (COVID-19) was first reported in December 2019 in China and was soon declared a pandemic by the World Health Organization. Many elective and nonessential surgeries were postponed worldwide in an effort to minimize spread of disease, as well as to conserve resources. Our goal with this article is to review current practice guidelines in setting of the COVID-19 pandemic, based on available data and literature. METHODS: Websites pertaining to surgical and medical societies, and government agencies were reviewed, along with recently published literature to identify recommendations related to COVID-19 and plastic surgery procedures. RESULTS: Clinical practice modifications are recommended during the pandemic in outpatient and perioperative settings. Use of personal protective equipment is critical for aerosol-generating procedures, such as surgery in the head and neck area. Care for trauma and malignancy should continue during the pandemic; however, definitive reconstruction could be delayed for select cases. Specific recommendations were made for surgical treatment of cancer, trauma, and semiurgent reconstructive procedures based on available data and literature. CONCLUSIONS: The risk and benefit of each reconstructive procedure should be carefully analyzed in relation to necessary patient care, minimized COVID-19 spread, protection of health care personnel, and utilization of resources. Recommendations in this article should be taken in the context of each institute's resources and prevalance of COVID-19 in the region. It should be emphasized that the guidelines provided are a snapshot of current practices and are subject to change as the pandemic continues to evolve.


Subject(s)
Betacoronavirus , Coronavirus Infections/prevention & control , Infection Control/standards , Pandemics/prevention & control , Perioperative Care/standards , Plastic Surgery Procedures/standards , Pneumonia, Viral/prevention & control , Practice Guidelines as Topic , COVID-19 , Coronavirus Infections/transmission , Elective Surgical Procedures/methods , Elective Surgical Procedures/standards , Global Health , Health Care Rationing/methods , Health Care Rationing/standards , Health Services Accessibility/standards , Humans , Infection Control/methods , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Infectious Disease Transmission, Professional-to-Patient/prevention & control , Perioperative Care/methods , Pneumonia, Viral/transmission , Plastic Surgery Procedures/methods , Risk Assessment , SARS-CoV-2
6.
Aesthetic Plast Surg ; 42(1): 64-72, 2018 Feb.
Article in English | MEDLINE | ID: mdl-29270693

ABSTRACT

INTRODUCTION: Removal of tissue expanders (TE) or implants is a dire consequence of breast reconstruction, and has the potential to halt the reconstructive efforts. Our goals were to characterize a cohort of patients with TE/implant removal, to perform a time-based analysis, and to review the bacteriology associated with explanted devices. MATERIALS AND METHODS: Review of a prospectively maintained database was performed to identify patients who underwent TE/implant removal. Patient characteristics, surgical technique, adjuvant therapies, indications, complications, culture results were obtained. Data were analyzed according to timing of explantation. RESULTS: A total of 55 TE and implants were removed in 43 patients. Reasons for explantation were infection (58%), patient request (22%), and wound-related complications (20%). The majority of explantations occurred after 30 days (62%), and after Stage I (81%). Median days to explantation was 62. Patients of older age (p = 0.01) and higher BMI (p = 0.02) were more likely to undergo explantation after Stage I. The most commonly cultured organisms were S. epidermidis (10.9%), S. aureus (10.9%) and P. aeruginosa (10.9%). Antibiotic resistance was commonly encountered for ampicillin, cefazolin, penicillin, and erythromycin. CONCLUSION: Infection is the most common reason for explantation after prosthetic breast reconstruction. Patients should be carefully monitored for a prolonged period of time after Stage I, as the majority of explantations occur in this stage but beyond 30 days. For oral treatment, fluoroquinolones and trimethoprim-sulfamethoxazole and for IV treatment a combination of vancomycin or daptomycin with piperacillin-tazobactam or imipenems/carbapenems appear to be appropriate choices according to our culture results. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Subject(s)
Breast Implants/adverse effects , Mammaplasty/methods , Prosthesis-Related Infections/drug therapy , Tissue Expansion Devices/adverse effects , Adult , Anti-Bacterial Agents/therapeutic use , Breast Neoplasms/pathology , Breast Neoplasms/surgery , Cancer Care Facilities , Cohort Studies , Databases, Factual , Device Removal/methods , Female , Follow-Up Studies , Humans , Mammaplasty/adverse effects , Mastectomy/methods , Middle Aged , Prosthesis Failure , Prosthesis-Related Infections/diagnosis , Prosthesis-Related Infections/epidemiology , Reoperation/methods , Retrospective Studies , Risk Factors , Time Factors , Treatment Outcome
7.
J Plast Reconstr Aesthet Surg ; 70(6): 741-751, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28356202

ABSTRACT

BACKGROUND: Tissue expanders (TEs) can be used to assist primary closure of complicated hernias and large abdominal wall defects. However, there is no consensus regarding the optimal technique, use, or associated risk of TE in abdominal wall reconstruction. METHODS: A systematic search of PubMed and Embase databases was conducted to identify articles reporting abdominal wall reconstruction with TE techniques. English articles published between 1980 and 2016 were included on the basis of the following inclusion criteria: two-stage TE surgical technique, >3 cases, reporting of postoperative complications, hernia recurrence, and patient-based clinical data. RESULTS: Fourteen studies containing 103 patients (85 adults and 18 children) were identified for analysis. Most patients presented with a skin-grafted ventral hernia (n = 86). The etiology of the hernia was from trauma or prior abdominal surgery. The remaining patients had TE placed before organ transplantation (n = 12) or for congenital abdominal wall defects (n = 5). The location for expander placement was subcutaneous (n = 74), between the internal and external obliques (n = 26), posterior to the rectus sheath (n = 2), and intra-peritoneal (n = 1). Postoperative infections and implant-related problems were the most commonly reported complications after Stage I. The most common complication after Stage II was recurrent hernia, which was observed in 12 patients (11.7%). Five patients with TE died. Complications and mortality were more prevalent in children, immunosuppressed patients, and those with chronic illnesses. CONCLUSIONS: Tissue expansion for abdominal wall reconstruction can be successfully used for a variety of carefully selected patients with an acceptable complication and risk profile.


Subject(s)
Abdominal Wall/surgery , Hernia, Ventral/surgery , Herniorrhaphy/methods , Tissue Expansion/methods , Adult , Child , Herniorrhaphy/adverse effects , Humans , Postoperative Care , Postoperative Complications , Recurrence , Reoperation , Risk Factors , Tissue Expansion/adverse effects
8.
J Plast Reconstr Aesthet Surg ; 70(6): 752-758, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28286041

ABSTRACT

BACKGROUND: We report the long-term outcome analysis of 12 patients who underwent two-stage abdominal wall reconstruction using combined submuscular tissue expansion and anterior components separation (CS) technique. METHODS: Outcome measures were (1) the patients were assessed for the presence or absence of recurrence; (2) patient-reported outcomes on physical functioning in relation with the abdominal wall reconstruction were evaluated using the SF 36-item health survey. RESULTS: The mean age, average expansion volume, and mean time expansion were 37.5 years, 1250 cc, and 9.5 weeks, respectively. The average soft tissue deficiency size was 15.5 (width) × 19.5 (length) cm2. The average fascial defect was 17 (width) × 21.5 (length) cm2. No mesh-assisted technique was required. Primary closure was obtained in all. The average follow-up was 39.6 months. Hernia recurrence was noted in one patient (8.3%). All 12 patients completed the SF 36-item health survey. Moreover, 75% of the patients reported 100%, indicating "Not limited in vigorous activities," and 25% indicated "limited a little." All patients reported 100% "not limited at all" in lifting or carrying groceries, climbing several flights of stairs, climbing one flight of stairs, bending, kneeling, stooping, walking more than a mile, walking several blocks, walking one block, bathing, or dressing. CONCLUSIONS: Parietal laxity obtained with tissue expansion increases the possibility of direct closure of the fascial layer, skin, and subcutaneous tissue components. Combined use of tissue expansion and CS may result in favorable long-term outcomes as evidenced by patient-reported physical functioning data and low rate of hernia recurrence.


Subject(s)
Abdominal Wall/surgery , Hernia, Ventral/surgery , Herniorrhaphy/methods , Tissue Expansion/methods , Activities of Daily Living , Adult , Female , Follow-Up Studies , Herniorrhaphy/adverse effects , Humans , Male , Middle Aged , Postoperative Complications , Recurrence , Tissue Expansion/adverse effects , Treatment Outcome
9.
J Plast Reconstr Aesthet Surg ; 69(9): 1234-47, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27425000

ABSTRACT

BACKGROUND: Free vascularized lymph node transfer (VLNT) is a relatively novel technique for treatment of lymphedema. The purpose of this systematic review was to evaluate the current evidence on VLNT and to determine if there is objective data concerning improved outcomes. METHODS: A literature search of PubMed, EMBASE and CENTRAL electronic databases was conducted to identify articles written in the English language on VLNT for treatment of lymphedema. Publications were selected according to inclusion criteria. Papers reporting adjunct techniques and those that did not describe outcomes were excluded. Data including patient demographics, surgical technique, complications and outcomes were extracted. A quality score was calculated for each article. RESULTS: Eighteen studies were included with an overall study population of 305 patients. Mean quality score of articles was 5.3 with levels of evidence range from II to IV. Among 182 patients who underwent limb circumference assessment, 165 (91%) showed postoperative improvement. Reduction of limb volume was noted in 98 of 114 (86%) patients. Ninety two patients underwent lymphoscintigraphy/lymphangiography and 55 (60%) demonstrated moderate or significant improvement of flow. Patient satisfaction was questioned in 105 patients and with exception of 7 patients, all reported a high satisfaction level with significant relief in symptoms and improved quality of life. Publications also reported a reduction in infectious episodes. CONCLUSION: VLNT appears to provide improvement in lymphedema. More studies with standardized methods for reporting outcomes and uniform patient selection are needed to evaluate this technique thoroughly.


Subject(s)
Free Tissue Flaps , Lymph Nodes/transplantation , Lymphedema/surgery , Postoperative Complications , Breast Neoplasms/surgery , Female , Humans , Lymphedema/diagnosis , Lymphography , Lymphoscintigraphy , Mastectomy/adverse effects
10.
J Foot Ankle Surg ; 54(6): 1132-5, 2015.
Article in English | MEDLINE | ID: mdl-26234924

ABSTRACT

Degloving injury of the foot continues to be a challenging condition to treat. Despite current advancements in reconstructive options, most of these injuries can result in amputations, causing physical and emotional impairment. Few reports have been published on the management of these complex traumatic injuries. Typical reconstruction options have included skin grafting and reattachment of the avulsed skin. Many treating physicians have encountered challenging issues in predicting tissue viability, knowing the extent of the injury, and making a logical decision for limb salvage procedures. The present report provides an algorithm of our approach in managing degloving injuries. A case of foot degloving injury, treated by serial surgical operations with the dominant aim of salvaging the avulsed tissue, is presented. The avulsed portion of the foot, with no identifiable vessels for microsurgical reattachment, was defatted and used as a full-thickness skin graft. Negative pressure wound therapy and a dermal regeneration template were used as adjunct techniques to help obtain good soft tissue coverage. The traditional treatment methods for degloving injuries and the applications of new wound care technologies are discussed.


Subject(s)
Acellular Dermis , Dermis/physiology , Foot Injuries/surgery , Negative-Pressure Wound Therapy , Regeneration , Soft Tissue Injuries/surgery , Aged , Algorithms , Humans , Male , Skin/injuries , Skin/physiopathology , Skin Transplantation , Wound Healing
11.
Aesthet Surg J ; 35(2): 111-20, 2015 Feb.
Article in English | MEDLINE | ID: mdl-25681104

ABSTRACT

BACKGROUND: An in-depth understanding of the nuances of facial anatomy is the best means of preventing complications during facelift surgery. An appreciation of the operative details is complicated not only by the complexity of the anatomy but also by the variability in the nomenclature used. OBJECTIVES: The authors have attempted to clarify these issues by detailing the relationships of the ligaments of the lower face both to each other and to the marginal mandibular nerve. METHODS: The mandibular ligament, the platysma mandibular ligament, and the marginal mandibular nerve were identified in 22 cadaver halves. The gonial angle, and the lower mandibular border were used as perpendicular reference lines. RESULTS: The mean length, height, and depth of the mandibular ligament and the platysma mandibular ligament were calculated. The mean distance of the mandibular ligament from the gonial angle along the mandibular border was also noted:it was always located superior to the platysma mandibular ligament. The marginal mandibular "danger zone" was identified a quarter of the length of the mandibular body along the lower jaw border. Finally variability in nomenclature of the lower face ligaments was clarified. CONCLUSIONS: A topographic map of the structures of surgical importance in the lower face was constructed in the hope that this will prevent surgical errors during facelift surgery.


Subject(s)
Face/anatomy & histology , Ligaments/anatomy & histology , Mandible/anatomy & histology , Mandibular Nerve/anatomy & histology , Aged , Aged, 80 and over , Cadaver , Female , Humans , Male , Middle Aged
12.
Ann Plast Surg ; 75(6): 679-85, 2015 Dec.
Article in English | MEDLINE | ID: mdl-25003438

ABSTRACT

BACKGROUND: Over the last decade, microsurgeons have used a greater variety of more complex flaps. At the same time, microsurgeons have also become more interested in technology, such as indocyanine green (ICG) angiography, dynamic infrared thermography (DIRT), and photospectrometry, for preoperative planning and postoperative monitoring. These technologies are now migrating into the operating room, and are used to optimize flap design and to identify areas of hypoperfusion or problems with the anastomoses. Although relatively more has been published about ICG angiography, information is generally lacking about the intraoperative role of these techniques. METHODS: A systematic analysis of articles discussing intraoperative ICG angiography, DIRT, and photospectrometry was performed to better define the sensitivity, specificity, expected outcomes, and potential complications associated with these techniques. RESULTS: For intraoperative ICG angiography, the sensitivity was 90.9% (95% CI: 77.5-100) and the accuracy was 98.6% (95% CI: 97.6-99.7). The sensitivity of DIRT was 33% (95% CI: 11.3-64.6), the specificity was 100% (95% CI: 84.9-100), and the accuracy was 80% (95% CI: 71.2-89.7). The sensitivity of intraoperative photospectrometry was 92% (95% CI: 72.4-98.6), the specificity was 100% (95% CI: 98.8-100), and the accuracy was also 100% (95% CI: 98.7-100). CONCLUSION: These technologies for intraoperative perfusion assessment have the potential to provide objective data that may improve decisions about flap design and the quality of microvascular anastomoses. However, more work is needed to clearly document their value.


Subject(s)
Intraoperative Care/methods , Plastic Surgery Procedures , Surgical Flaps/blood supply , Angiography/methods , Coloring Agents , Humans , Indocyanine Green , Optical Imaging , Sensitivity and Specificity , Thermography/methods
13.
Microsurgery ; 35(2): 123-8, 2015 Feb.
Article in English | MEDLINE | ID: mdl-24934629

ABSTRACT

Postoperative flap monitoring is a key component for successful free tissue transfer. Tissue oxygen saturation measurement (TOx) with near-infrared spectrophotometry (NIRS) is a method used for this purpose. The aim of this study was to identify external variables that can affect TOx. Patients who had breast reconstruction with free flaps were monitored prospectively and intra-operative details were recorded. Flap TOx was recorded with NIRS pre-extubation, postextubation, and then every four hours for 36 hours. At each of these time points, blood oxygen saturation (SO2), amount of supplemental oxygen, and blood pressure were recorded. Thirty flaps were monitored. Initially, a significant trend over time was detected such that for every increase of 24 hours, TOx decreased on average by 2.1% (P = 0.025). However, when accounting for SO2 levels, this decrease was no longer significant (P = 0.19). An increase by 1% in SO2 produced an increase in TOx reading of 0.36 (P = 0.007). The amount of supplemental O2, systolic blood pressure, and diastolic blood pressure did not have a significant impact on TOx (P > 0.05). The TOx values were highest in the free TRAM flaps and were lower in decreasing order in the muscle-sparing TRAM, DIEP, and SIEA flaps (P > 0.05). The TOx values did not significantly correlate with vessel size, perforator number, or perforator row. Postoperative flap TOx was found to correlate with SO2 and was not significantly dependent on blood pressure, supplemental O2, or surgical variables. Careful interpretation of oximetry values is essential in decision making during postoperative flap monitoring.


Subject(s)
Free Tissue Flaps/blood supply , Mammaplasty , Oximetry/methods , Oxygen/metabolism , Postoperative Care/methods , Spectroscopy, Near-Infrared , Adult , Biomarkers/metabolism , Female , Free Tissue Flaps/physiology , Free Tissue Flaps/transplantation , Humans , Mammaplasty/methods , Middle Aged , Outcome Assessment, Health Care , Prospective Studies , Time Factors
14.
Dermatol Surg ; 40(10): 1103-7, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25229779

ABSTRACT

BACKGROUND: Refrigerant sprays have been widely used to reduce pain in the office setting. However, more recently, their use has been limited by both concern regarding flammability and questions of bacterial contamination. OBJECTIVE: We investigated the microbiological effect of 1,1,1,3,3 pentafluoropropane and 1,1,1,2-tetrafluoroethane when sprayed after povidone-iodine application in 50 volunteers. MATERIALS AND METHODS: In 50 volunteers, 3 cultures were taken (1) at time 0 before antiseptic application, (2) after povidone-iodine topical antiseptic, and (3) after spraying with vapocoolant. Cultures at 3 time intervals were analyzed in a blinded fashion, and Gram stains obtained when cultures were positive. RESULTS: Bacterial growth was found in 98% of cultures taken before antiseptic was applied (Group 1), in 28 cultures (56%) after povidone-iodine was applied, and in 24 cultures (48%) after spraying with vapocoolant. There was a statistically significant difference found between Group 1 (no antiseptic) and both Group 2 (after antiseptic but before vapocoolant) and Group 3 (after vapocoolant) (p < .001). CONCLUSION: The topical antiseptic povidone-iodine significantly reduces skin colonization when compared with unprepared skin (p < .001). The vapocoolant 1,1,1,3,3 pentafluoropropane and 1,1,1,2-tetrafluoroethane is sprayed on skin prepared with povidone-iodine; there is no statistically significant increase in bacterial colonization.


Subject(s)
Anti-Infective Agents, Local/administration & dosage , Hydrocarbons, Fluorinated/administration & dosage , Pain/prevention & control , Povidone-Iodine/administration & dosage , Skin/microbiology , Administration, Topical , Adult , Aerosols , Aged , Female , Healthy Volunteers , Humans , Male , Middle Aged , Prospective Studies , Young Adult
15.
J Reconstr Microsurg ; 30(6): 405-12, 2014 Jul.
Article in English | MEDLINE | ID: mdl-24752743

ABSTRACT

BACKGROUND: Operations for soft-tissue reconstruction, orthopedic, vascular, and other types of surgery can be complicated by unexpected skin flap necrosis. At present, surgeons utilize subjective clinical judgment and physical findings to estimate the potential for tissue compromise. As the validity of these subjective methods is questionable, there is a need for objective, quantitative tools to determine the risk of flap necrosis during surgery. METHODS: Three 9-month-old Yorkshire pigs were used for the study. Four laterally based random pattern fasciocutaneous flaps were dissected on each animal. After the flaps were elevated, a prototype oximeter (ViOptix Inc., Fremont, CA), was used to measure tissue oxygenation (StO2) at 2 cm intervals along the flaps. Measurements were performed immediately after the flaps were dissected, and again at the same points after they were sutured. The animals were reevaluated 4 days later, and assessed for areas of tissue necrosis. RESULTS: For each flap, StO2 at the base was compared with StO2 at the more distal points. The median delta StO2, as measured immediately after dissection, was -3.9% points for tissue that remained viable and -34.0% points for tissue that became necrotic (p = 0.039). After the flaps were sutured back to the chest wall, the median delta StO2 for tissue that remained viable was -1.7% points versus -24.7% points for tissue that became necrotic (p = 0.006). CONCLUSIONS: This new handheld surface sensor can be used to measure StO2 of skin flaps and may potentially reduce complications associated with unexpected tissue necrosis.


Subject(s)
Free Tissue Flaps/blood supply , Oximetry/instrumentation , Oxygen/metabolism , Animals , Feasibility Studies , Free Tissue Flaps/pathology , Graft Survival , Intraoperative Care , Logistic Models , Models, Animal , Necrosis , Swine
16.
Aesthet Surg J ; 34(4): 499-506, 2014 May 01.
Article in English | MEDLINE | ID: mdl-24633742

ABSTRACT

BACKGROUND: Cervicoplasty is an important component of aesthetic facial and neck surgery, but the fat content in this area has not been described. OBJECTIVES: The authors identify anatomic compartments of fat in the neck (specifically the areas relevant to surgical management), quantify the fat in each compartment, and describe the relationships between each compartment and the submandibular glands. METHODS: The skin was removed from 10 fresh cadaver heads. Each compartment of fat was weighed, along with the submandibular gland. Supraplatysmal fat was found between the skin and the platysma muscle, and it was compartmentalized into suprahyoid and infrahyoid fat. Subplatysmal fat was found deep to the platysma and between the medial edges of the anterior digastric in the midline; this fat also fell into suprahyoid and infrahyoid compartments. The "very deep" fat was deep to the anterior digastric muscles and submandibular gland, and adherent to the strap muscles. RESULTS: On average, supraplatysmal fat represented 44.7% of the fat in the neck, the subplatysmal fat represented 30.7%, and the submandibular gland represented 24.5%. The very deep fat was scant, representing less than 1% of the fat in the neck. CONCLUSIONS: This anatomic study provides a comprehensive review of fat in the neck, and the results should serve as an additional guide as surgeons approach this challenging area in surgical rejuvenation.


Subject(s)
Adiposity , Neck/anatomy & histology , Subcutaneous Fat/anatomy & histology , Aged , Aged, 80 and over , Cadaver , Cervicoplasty , Female , Humans , Male , Middle Aged , Neck/surgery , Rejuvenation , Subcutaneous Fat/surgery
17.
J Reconstr Microsurg ; 30(6): 371-4, 2014 Jul.
Article in English | MEDLINE | ID: mdl-24535678

ABSTRACT

BACKGROUND: Venous grafting has been widely used in microsurgical training. Different types of vascular grafts have been described in experimental models. In this study we describe for the first time the Y- and X-shaped vein grafts (YVG, XVG) with accompanying drain-out branches as a new tool for the microsurgical training and free flap applications in rats. METHODS: Twelve adult male Lewis rats were used in this study. The dissections were performed to determine the average diameter and harvestable length of vein grafts in eight rats. In four rats vein grafts were applied for bridging of the common carotid artery gap, whereas the drain-out branches were used as the arterial source for single and bilateral free groin flap applications. The venous anastomoses of groin flaps were performed in end-to-end fashion to the external jugular vein and its branches. The patency of anastomoses was checked 72 hours after repair. RESULTS: The average length of the harvestable vein branches ranged between 5.2 to 11.8 mm. The average surgery time for repair of the arterial gap with the vein grafts was 40 minutes. The ischemia time for single and bilateral groin flap transfer using YVG and XVG was 30 and 70 minutes, respectively. The patency of the interpositional vein graft was 100%. Flap survival rates were 50%. CONCLUSIONS: These vein grafts can be used as an alternative technique for reconstruction of tissue defects that require arterial gap repair with single or multiple free flap applications and also as a new microsurgical training model.


Subject(s)
Carotid Artery Injuries/surgery , Carotid Artery, Common/surgery , Free Tissue Flaps/blood supply , Jugular Veins/transplantation , Microsurgery/methods , Anastomosis, Surgical/methods , Animals , Feasibility Studies , Graft Survival , Jugular Veins/anatomy & histology , Male , Operative Time , Rats, Inbred Lew , Vascular Patency
18.
Ann Plast Surg ; 72(1): 13-22, 2014 Jan.
Article in English | MEDLINE | ID: mdl-23542834

ABSTRACT

Obesity, which is becoming endemic in the United States, causes a significant challenge for reconstructive surgeons. This study evaluates postoperative complications and impact of weight loss in the high body mass index (BMI) population undergoing breast reconstruction with abdominal free flaps. A retrospective review of 182 consecutive patients was performed. Patients were divided into groups according to their BMI at the time of surgery (preoperative BMI) and presence of weight loss, and data were compared among groups. Multivariate analysis of effect of preoperative BMI on complications revealed that overall flap (P = 0.008) and donor (P = 0.016) complication rates were significantly higher in the obese group. Analysis of preoperative weight loss did not yield a statistically significant reduction in flap (P = 0.5161) or donor (P = 0.8034) complication rates. Univariate analysis showed that higher preoperative BMI is associated with higher risk of systemic complications (P = 0.027). It is important to inform patients preoperatively that weight loss, although beneficial for ease of procedure and quality of life, does not diminish their increased risk of complications. Body mass index during surgery is the most important predictor of complications.


Subject(s)
Body Mass Index , Free Tissue Flaps , Mammaplasty/methods , Obesity/complications , Postoperative Complications/etiology , Weight Loss , Abdomen , Adult , Female , Follow-Up Studies , Humans , Logistic Models , Middle Aged , Multivariate Analysis , Odds Ratio , Overweight/complications , Retrospective Studies , Risk Factors
19.
Aesthet Surg J ; 34(1): 16-21, 2014 Jan 01.
Article in English | MEDLINE | ID: mdl-24334305

ABSTRACT

BACKGROUND: The great auricular nerve (GAN) is the most commonly injured nerve during facelift surgery. Although rare, injury can result in long-term sequelae. OBJECTIVES: Previous reports have described the nerve's location at the midbelly of the sternocleidomastoid muscle (SCM) or at its emergence from underneath the SCM. The purpose of our study was to identify the superior course of the great auricular nerve as it applies to facelift. METHODS: Thirteen fresh cadavers were dissected. A vertical line through the midlobule was drawn perpendicular to the Frankfort's horizontal, acting as a reference to the course of the GAN. Transparent paper overlay tracings were then done to record each nerve's location. The distance from the bony external auditory canal (EAC) to the nerve was measured at the anterior muscle border, at the midbelly of the SCM, and as the nerve emerged from under the SCM. Branching patterns of the nerve and its relation to the external jugular vein were identified. RESULTS: In 100% of the dissections, the superior course of the GAN fell within a 30-degree angle constructed using the vertical limb perpendicular to the Frankfurt horizontal and a second limb drawn posteriorly from the midlobule. The distance from the EAC to the nerve was 4.9 ± 1.1 cm at the anterior muscle border, 7.3 ± 1.0 cm at the midbelly of the SCM, and 9.8 ± 1.2 cm at the GAN's emergence from under the SCM. Four types of branching patterns were identified. CONCLUSIONS: The 30-degree angle described above rapidly and accurately identifies the nerve's location.


Subject(s)
Ear Auricle/innervation , Peripheral Nerve Injuries/prevention & control , Rhytidoplasty/adverse effects , Rhytidoplasty/methods , Aged , Aged, 80 and over , Anatomic Landmarks , Cadaver , Ear Canal/anatomy & histology , Female , Humans , Jugular Veins/anatomy & histology , Male , Middle Aged , Neck Muscles/anatomy & histology , Peripheral Nerve Injuries/etiology , Treatment Outcome
20.
Plast Reconstr Surg ; 133(4): 763-773, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24352211

ABSTRACT

BACKGROUND: The goal of this study was to evaluate the relationship between body mass index, preoperative weight loss, and patient satisfaction in breast reconstruction with abdominally based free flaps. METHODS: A custom survey with overall, breast, and abdomen questions was sent to patients who underwent abdominally based free flap breast reconstruction over the past 4 years. Clinical data were collected for patients who returned surveys. Data analysis was performed based on body mass index and percentage weight loss before surgery. RESULTS: One hundred seventy-nine surveys were sent. Ninety-two patients (51.4 percent) responded. Normal weight patients versus overweight patients did not have statistically significant differences in any satisfaction scores. Overweight patients had higher overall satisfaction (p = 0.01), breast-specific satisfaction (p = 0.01), and abdomen-specific satisfaction (p = 0.02) compared with obese patients. Normal weight patients had higher breast-specific satisfaction (p = 0.05) and abdomen-specific satisfaction (p = 0.03) scores compared with obese patients. Patients with significant preoperative weight loss were more satisfied with feeling of breasts in clothes (p = 0.01), social appearance (p = 0.05), and current abdominal appearance (p = 0.01) compared with patients with moderate preoperative weight loss. Overall, breast- and abdomen-specific satisfaction scores decreased with increase in pannus thickness. CONCLUSIONS: Patient satisfaction with abdominally based free flap breast reconstruction was highest in patients with normal body mass index and lowest in obese patients. Overweight or obese patients should be encouraged to participate in healthy weight loss programs to achieve improved postoperative satisfaction. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.


Subject(s)
Body Mass Index , Free Tissue Flaps , Mammaplasty/methods , Patient Satisfaction , Abdomen , Adult , Breast Neoplasms/epidemiology , Breast Neoplasms/surgery , Comorbidity , Female , Humans , Obesity/epidemiology , Preoperative Period , Retrospective Studies , Surveys and Questionnaires , Weight Loss
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