Determination of safety margin of nasal septum osteotomy for sphenoid sinus in cleft lip and palate patients.

BACKGROUND: Nasal septum osteotomy is used for separating the nasal septum and maxilla during a Le Fort I osteotomy. If this osteotomy is applied too high or is tilted into the nasal cavity, the sphenoid sinus and various adjacent vital structures may be damaged, and serious bleeding, neurological complications, blindness or even death may occur. The aim of this study is to determine the safety margin of the nasal septum osteotomy for sphenoid sinus during the Le Fort I surgery in cleft lip and palate (CLP) patients. METHODS: Twenty cleft lip and palate (the CLP group) and 20 healthy individuals (the control group) were included in this study. Three values (two lines and an angle) were measured by cone beam computed tomography (CBCT). The first line is the line passing through the junction of the spina nasalis anterior point and the lower point of the perpendicular lamina of the palatine bone. The undersired line is the line passing through the junction of the spina nasalis anterior point and the lower anterior border of the base of the sphenoid sinus. The osteotomy angle is the angle between these two lines. RESULTS: In the control group; a surgical line of 44.11-61.14 mm (mean 51.91 ± 4.32), an undesired line of 52.48-69.58 mm (mean 59.14 ± 5.08) and an angle of 18.22-27.270 (mean 22.66 ± 2.55) were found, while in the CLP group, a surgical line of 34.53-51.16 mm (mean 43.38 ± 4.79), an undesired line of 46.86-61.35 mm (mean 55.02 ± 3.24) and an angle of 17.60-28.810 (mean 22.60 ± 2.81) were found. CONCLUSIONS: Although the angle to the sphenoid sinus was not significantly affected by CLP, careful planning and consideration of these anatomical differences are crucial to prevent complications and ensure the safety of Le Fort I surgery in CLP patients. Further research with larger sample sizes and subgroup analysis of unilateral and bilateral CLP cases is needed to improve our understanding of these anatomical variations and improve surgical approaches to individuals with CLP undergoing orthognathic procedures.

Effects of essential oils on egg production and feed efficiency as influenced by laying hen breed: A meta-analysis.

Background and Aim: Successful rearing of laying hens to achieve optimal egg production is an endeavor that often faces various constraints and challenges, such as infectious diseases, environmental stressors, and fluctuations in feed quality. The incorporation of essential oils (EOs) into the diet of laying hens has attracted considerable attention in recent years. Therefore, our study aimed to evaluate the efficacy of EO inclusion in laying hen diets by considering the effects of production phase and breed on performance, egg quality, serum biochemistry, gut health, and antioxidant activity. Materials and Methods: The articles were obtained from the Web of Science, Scopus, Science Direct, and PubMed using the search terms "essential oils," "laying hens," and "phytobiotics." Data from 27 articles and 71 experiments were grouped according to laying hen production phase and breed in the database. The EO levels ranged from 0 to 1000 mg/kg, with thymol and carvacrol being the major EOs. A mixed model was used to analyze the data. Random effects were applied to the treatment, and fixed effects were applied to EO level, production phase, and breed. Results: Egg production, feed intake, feed efficiency, eggshell quality, villus height, crypt depth, superoxide dismutase, and glutathione peroxidase levels increased linearly (p = 0.05) and egg weight and mass increased quadratically (p < 0.05) with increasing EO concentrations. An interaction was observed between the EO level egg production and feed conversion ratio (p = 0.05). Serum glucose, cholesterol, and malondialdehyde levels decreased with increasing EO concentrations (p < 0.05). Conclusions: The inclusion of EOs effectively increased egg production, feed efficiency, egg weight, egg mass, eggshell quality, oxidative enzymes, and intestinal health. In addition, the proportion of dietary EOs in lightweight laying hens was higher than that in semi-heavy-weight laying hens in improving egg production and feeding efficiency.

A Meta-analysis of Optimum Level of Dietary Nanoselenium on Performances, Blood Constituents, Antioxidant Activity, Carcass, and Giblet Weight of Broiler Chickens.

Contradictory reports regarding the effects of nanoselenium (NanoSe) on the performance of broiler chickens may occur. Therefore, the optimum supplementation of NanoSe doses needs to be determined. The current meta-analysis study was aimed at evaluating the effectiveness and the optimum doses of NanoSe supplementation in broiler diets on performance, blood constituents, carcass, and giblet weight by considering breed and sex. The database was obtained from online scientific publications by searching through search engines such as Scopus, Web of Science, Google Scholar, and PubMed by entering the keywords nanoselenium, performance, antioxidants, and broiler. A total of 25 articles were included in the meta-analysis database. The study group was treated as a random effect while NanoSe dose, breed, and sex were treated as fixed effects. Daily body weight gain, carcass weight, and breast weight increased quadratically (P < 0.05), and FCR decreased quadratically (P < 0.05) in the starter and cumulative periods with increasing NanoSe supplementation. NanoSe supplementation tended to decrease cumulative feed intake linearly (P < 0.1) and decreased (P < 0.05) abdominal fat, albumin, red blood cells, ALT, and MDA levels. In contrast, levels of total protein, globulin, glucose, AST, white blood cells, cholesterol, triglyceride, and the weight of the liver, heart, gizzard, bursa of Fabricius, thymus, and spleen were not affected by NanoSe supplementation. Increasing the dose of NanoSe increased (P < 0.05) the GSHPx enzyme and Se concentration in breast muscle and liver and tended to enhance (P < 0.01) the CAT enzyme. It is concluded that a proper dose of NanoSe supplementation in a broiler diet improves body weight gain, feed efficiency, carcass, and breast weight without adverse effects on giblets. Dietary NanoSe elevates Se concentration in the breast muscle and liver and antioxidant activity. The current meta-analysis shows that the optimum dose for body weight gain and FCR is 1 to 1.5 mg/kg.

Effects of maize silage feeding on growth performance, carcass characteristics, digestive system length, chemical composition, and meat quality of domestic geese.

This study aimed to explore the effects of corn silage (CS) on growth performance, carcass characteristics, digestive system length, and some meat quality traits of geese. A total of 35 19-week-old Turkish indigenous male geese with similar body weight were randomly divided into five groups with individual pens of seven geese per group and fed for 84 D. The treatments were composed of a basal diet (100% concentrate feed) without corn silage (0CS), 10% CS + 90% concentrate feed (10CS), 20% corn silage + 80% concentrate feed (20CS), 30% corn silage + 70% concentrate feed (30CS), and 40% corn silage + 60% concentrate feed (40CS). Dietary CS supplementation did not affect growth performance, dressing percentage, liver and gizzard weights, digestive system length of geese, and the organoleptic quality characteristics of meat. The 0CS and 20CS geese had a higher instrumental hardness value than other treatment geese (p < 0.05). Also, the 40CS group had the lowest hardness value (p < 0.05). Adhesiveness value was lower in the 0CS group compared to all silage treatments (p < 0.05). Gumminess value was lower in the 40CS group compared to the control group (p < 0.05). The 10CS treatment reduced the L value of thigh and breast meat compared with those of the other treatments (p < 0.05). The a and b color values and pH values of breast and thigh meats were not affected by dietary CS supplementation (p > 0.05). Fat content of the meat decreased in the 30CS treatment compared to 0CS (p < 0.05). The results of the present study suggest that corn silage could be used up to 40% in the Turkish goose variety diet, without affecting the performance and meat quality, and thus, geese can be produced more economically.

Dietary Phytogenic Extracts Favorably Influence Productivity, Egg Quality, Blood Constituents, Antioxidant and Immunological Parameters of Laying Hens: A Meta-Analysis.

The present study aimed to assess the impact of dietary phytogenic extracts on laying hen productivity, egg quality, blood constituents, antioxidant, and immunological parameters through a meta-analytical approach. A total of 28 articles (119 data points) reporting the influence of dietary phytogenic extracts on the productive performance, egg quality, blood constituents, immunological, and antioxidant parameters of laying hens were embedded into a database. Statistical analysis was performed using a mixed model, with different studies treated as random effects and phytogenic extract levels treated as fixed effects. This meta-analysis revealed that dietary phytogenic extracts quadratically (p < 0.05) improved egg production and egg mass as well as decreased (p < 0.05) the feed conversion ratio (FCR) with no adverse effect on egg weight and egg quality. Feed intake and egg yolk percentage tended to increase linearly (p < 0.1). Total serum cholesterol and low-density lipoprotein (LDL) declined quadratically (p < 0.001 and p < 0.05, respectively), high-density lipoprotein (HDL) increased linearly (p < 0.001), and malondialdehyde (MDA) decreased linearly (p < 0.01), with increasing levels of dietary phytogenic extract. In addition, immunoglobulin G (IgG), immunoglobulin A (IgA), glutathione peroxidase (GSH-Px), and total superoxide dismutase (TSOD) increased linearly (p < 0.05) in line with the increase in dietary phytogenic extract level. It was concluded that the inclusion of phytogenic extracts in the diet of laying hens had a positive effect on productive performance, feed efficiency, egg mass, immunity, and antioxidant activity without interfering with egg quality. The optimum level of feed photogenic extract for egg production and feed efficiency was determined to be around 300 mg/kg feed.

Performance, carcass, gastrointestinal tract and meat quality traits, and selected blood parameters of broilers fed diets supplemented with humic substances.

BACKGROUND: The effects of humic substances (HS) on quality traits (colour, water-holding capacity, and pH) of breast and thigh meats and on blood minerals (calcium and phosphorus) and on metabolites (glucose, total protein, triglyceride and cholesterols) as well as on the performance, carcass, and gastrointestinal tract (gut) traits of broilers were studied. In total, 480 male chicks (ROSS 308) were allocated to four treatments, each with five replicates containing 24 birds. While control birds were fed a diet (mash form) with no additives (0 HS), other treatment birds were fed with diets containing HS at 0.5 (0.5 HS), 1.0 (1 HS) or 1.5 (1.5 HS) g kg(-1) from 1 to 42 days of age. RESULTS: The body and carcass weights and feed efficiency increased (P < 0.05) by 1.5 HS, and blood cholesterol decreased (P < 0.05) by 1 HS and 1.5 HS compared to 0 HS. The 0.5 HS decreased (P < 0.10) low-density lipoprotein compared to 0 HS. The 0.5 HS resulted in thigh meat and breast meat that were lighter and darker than those found in the other groups and 1.5 HS respectively (P < 0.01). CONCLUSION: Feeding with a diet containing HS caused a measurable variation in the meat quality and blood cholesterol as well as the performance, carcass, and gut traits of broilers.