Bands renormalization and superconductivity in the strongly correlated Hubbard model using composite operators method.

We use the composite operator method (COM) to analyze the strongly correlated repulsive Hubbard model, investigating the effect of nearest-neighbor hoppings up to fourth order on a square lattice. We consider two sets of self-consistent equations, one enforcing the Pauli principle and the other imposing charge-charge, spin-spin, and pair-pair correlations using a decoupling scheme developed by Roth (1969Phys. Rev.184451-9). We extract three distinct solutions from these equations: COM1 and COM2 by imposing the Pauli principle and one from Roth decoupling. An overview of the method studying the validity of particle-hole symmetry and the Luttinger theorem for each solution is presented. Additionally, we extend the initial basis to study superconductivity, concluding that it is induced by the Van Hove singularity. Finally, we include higher-order hoppings using realistic estimates for tight binding parameters and compare our results with ARPES measurements on cuprates.

Acoustic Droplet Vaporization of Perfluorohexane Emulsions Induced by Heterogeneous Nucleation at an Ultrasonic Frequency of 1.1 MHz.

Droplets made of liquid perfluorocarbon undergo a phase transition and transform into microbubbles when triggered by ultrasound of intensity beyond a critical threshold; this mechanism is called acoustic droplet vaporization (ADV). It has been shown that if the intensity of the signal coming from high ultrasonic harmonics are sufficiently high, superharmonic focusing is the mechanism leading to ADV for large droplets (>3 µm) and high frequencies (>1.5 MHz). In such a scenario, ADV is initiated due to a nucleus occurring at a specific location inside the droplet volume. But the question on what induces ADV in the case of nanometer-sized droplets and/or at low ultrasonic frequencies (<1.5 MHz) still remains. We investigated ADV of perfluorohexane (PFH) nano- and microdroplets at a frequency of 1.1 MHz and at conditions where there is no superharmonic focusing. Three types of droplets produced by microfluidics were studied: plain PFH droplets, PFH droplets containing many nanometer-sized water droplets, and droplets made of a PFH corona encapsulating a single micron-sized water droplet. The probability to observe a vaporization event was measured as a function of acoustic pressure. As our experiments were performed on droplet suspensions containing a population of monodisperse droplets, we developed a statistical model to extrapolate, from our experimental curves, the ADV pressure thresholds in the case where only one droplet would be insonified. We observed that the value of ADV pressure threshold decreases as the radius of a plain PFH droplet increases. This value was further reduced when a PFH droplet encapsulates a micron-sized water droplet, while the encapsulation of many nanometer-sized water droplets did not modify the threshold. These results cannot be explained by a model of homogeneous nucleation. However, we developed a heterogeneous nucleation model, where the nucleus appears at the surface in contact with PFH, that successfully predicts our experimental ADV results.

Novel experimental setup for megahertz X-ray diffraction in a diamond anvil cell at the High Energy Density (HED) instrument of the European X-ray Free-Electron Laser (EuXFEL).

The high-precision X-ray diffraction setup for work with diamond anvil cells (DACs) in interaction chamber 2 (IC2) of the High Energy Density instrument of the European X-ray Free-Electron Laser is described. This includes beamline optics, sample positioning and detector systems located in the multipurpose vacuum chamber. Concepts for pump-probe X-ray diffraction experiments in the DAC are described and their implementation demonstrated during the First User Community Assisted Commissioning experiment. X-ray heating and diffraction of Bi under pressure, obtained using 20 fs X-ray pulses at 17.8 keV and 2.2 MHz repetition, is illustrated through splitting of diffraction peaks, and interpreted employing finite element modeling of the sample chamber in the DAC.

Awareness of Chlamydia trachomatis infection by people attending a sexual transmitted infection (STI) clinic and missed opportunities for screening in a primary health care setting.

OBJECTIVES: To characterize awareness of Chlamydia trachomatis infection among persons consulting in a screening center in Ille-et-Vilaine, France, as well as the missed opportunities for screening in a primary health care setting during the 6 months preceding a diagnosis. PATIENTS AND METHOD: Cross-sectional study including persons over 15 years of age consulting in the centers of Rennes and Saint-Malo between 4 April 2019 and 1 July 2019 with data collection by self-administered questionnaire and telephone interview. RESULTS: We included 723 persons with a median age of 22 years. A third of them (34%) had never heard of Chlamydia, while 36% thought that testing sexually active youth was recommended. Among the 37 infected persons we were able to contact and interview, 9 (24.3%) had missed at least one opportunity for screening. CONCLUSION: People's lack of awareness and failure to appropriate recent recommendations by professionals could constitute an obstacle to large-scale screening.

Ultrasound-triggered delivery of paclitaxel encapsulated in an emulsion at low acoustic pressures.

We investigated the in vitro ultrasound-triggered delivery of paclitaxel, a well known anti-cancerous drug, encapsulated in an emulsion and in the presence of CT26 tumor cells. The emulsion was made of nanodroplets, whose volume comprised 95% perfluoro-octyl bromide and 5% tributyl O-acetylcitrate, in which paclitaxel was solubilized. These nanodroplets, prepared using a high-pressure microfluidizer, were stabilized by a tailor-made and recently patented biocompatible fluorinated surfactant. The delivery investigations were performed at 37 °C using a high intensity focused ultrasound transducer at a frequency of 1.1 MHz. The ultrasonic pulse was made of 275 sinusoidal periods and the pulse repetition frequency was 200 Hz with a duty cycle of 5%. The measured viabilities of CT26 cells showed that paclitaxel delivery was achievable for peak-to-peak pressures of 0.4 and 3.5 MPa, without having to vaporize the perfluorocarbon part of the droplet or to induce inertial cavitation.

Pseudo-spin skyrmions in the phase diagram of cuprate superconductors.

Topological states of matter are at the root of some of the most fascinating phenomena in condensed matter physics. Here we argue that skyrmions in the pseudo-spin space related to an emerging SU(2) symmetry enlighten many mysterious properties of the pseudogap phase in under-doped cuprates. We detail the role of the SU(2) symmetry in controlling the phase diagram of the cuprates, in particular how a cascade of phase transitions explains the arising of the pseudogap, superconducting and charge modulation phases seen at low temperature. We specify the structure of the charge modulations inside the vortex core below T c, as well as in a wide temperature region above T c, which is a signature of the skyrmion topological structure. We argue that the underlying SU(2) symmetry is the main structure controlling the emergent complexity of excitations at the pseudogap scale T *. The theory yields a gapping of a large part of the anti-nodal region of the Brillouin zone, along with q = 0 phase transitions, of both nematic and loop currents characters.

Synthesis of FeH5: A layered structure with atomic hydrogen slabs.

High pressure promotes the formation of polyhydrides with unusually high hydrogen-to-metal ratios. These polyhydrides have complex hydrogenic sublattices. We synthesized iron pentahydride (FeH5) by a direct reaction between iron and H2 above 130 gigapascals in a laser-heated diamond anvil cell. FeH5 exhibits a structure built of atomic hydrogen only. It consists of intercalated layers of quasicubic FeH3 units and four-plane slabs of thin atomic hydrogen. The distribution of the valence electron density indicates a bonding between hydrogen and iron atoms but none between hydrogen atoms, presenting a two-dimensional metallic character. The discovery of FeH5 suggests a low-pressure path to make materials that approach bulk dense atomic hydrogen.

Local particle-hole pair excitations by SU(2) symmetry fluctuations.

Understanding the pseudo-gap phase which opens in the under-doped regime of cuprate superconductors is one of the most enduring challenges of the physics of these compounds. A depletion in the electronic density of states is observed, which is gapping out part of the Fermi surface, leading to the formation of mysterious lines of massless excitations- the Fermi arcs. Here we give a new theoretical account of the physics of the pseudo-gap phase in terms of the emergence of local patches of particle-hole pairs generated by SU(2) symmetry fluctuations. The proliferation of these local patches accounts naturally for the robustness of the pseudo-gap phase to disturbances like disorder or magnetic field and is shown to gap out part of the Fermi surface, leading to the formation of the Fermi arcs. Most noticeably, we show that these patches induce a modulated charge distribution on the Oxygen atoms, in remarkable agreement with recent X-ray and STM observations.

Charge orders, magnetism and pairings in the cuprate superconductors.

We review the recent developments in the field of cuprate superconductors with special focus on the recently observed charge order in the underdoped compounds. We introduce new theoretical developments following the study of the antiferromagnetic quantum critical point in two dimensions, in which preemptive orders in both charge and superconducting (SC) sectors emerge, that are in turn related by an SU(2) symmetry. We consider the implications of this proliferation of orders in the underdoped region, and provide a study of the type of fluctuations which characterize the SU(2) symmetry. We identify an intermediate energy scale where the SC fluctuations are dominant and argue that they are unstable towards the formation of a resonant excitonic state at the pseudogap temperature T (*). We discuss the implications of this scenario for a few key experiments.

Perfluorocarbon nanodroplets stabilized by fluorinated surfactants: characterization and potentiality as theranostic agents.

We aim to produce emulsions that can act as contrast agents and drug carriers for cancer imaging and therapy. To increase tumor detection and decrease drug side effects, it is desirable to take advantage of the enhanced permeability and retention effect that allows nanoparticles to accumulate in tumor tissues. To do so, the emulsion droplets need to be small enough and stable over time in addition to enhancing image contrast and carrying a drug payload. In the present study, we have investigated the properties and potentiality as theranostic agents of perfluorocarbon emulsions stabilized by a biocompatible fluorinated surfactant called FTAC. To obtain better control of our system, the synthesis of those surfactants was studied and their physico-chemical properties were explored in different configurations such as micelles, in the perfluorocarbon droplet shell and at water/air and water/perfluorocarbon interfaces. The originality of this work lies in the determination of numerous characteristics of emulsions and fluorinated surfactants including surface tension, interfacial tension, critical micelle concentration, adiabatic compressibility, density, size distribution (aging studies), and ultrasonic echogenicity. These characterization studies were conducted using different types of FTAC and several perfluorocarbons (perfluoropentane, perfluorohexane, and perfluorooctyl bromide). We have also shown that a hydrophobic drug could be encapsulated in the FTAC-stabilized perfluorocarbon droplets thanks to triacetin addition. Finally, the perfluorocarbon emulsions were detectable in vitro by a clinical 3 T MRI scanner, equipped with a double frequency 19F/1H transmit-receive coil.

Equivalence of single-particle and transport lifetimes from hybridization fluctuations.

Single band theories of quantum criticality successfully describe a single-particle lifetime with non-Fermi liquid temperature dependence, but they fail to obtain a charge transport rate with the same dependence unless the interaction is assumed to be momentum independent. Here we demonstrate that a quantum critical material, with a long-range mode that transmutes electrons between light and heavy bands, exhibits a quasilinear temperature dependence for both the single-particle and the charge transport lifetimes, despite the strong momentum dependence of the interaction.

Modulated spin liquid: a new paradigm for URu2Si2.

We argue that near a Kondo breakdown critical point, a spin liquid with spatial modulations can form. Unlike its uniform counterpart, we find that this occurs via a second order phase transition. The amount of entropy quenched when ordering is of the same magnitude as for an antiferromagnet. Moreover, the two states are competitive, and at low temperatures are separated by a first order phase transition. The modulated spin liquid we find breaks Z4 symmetry, as recently seen in the hidden order phase of URu2Si2. Based on this, we suggest that the modulated spin liquid is a viable candidate for this unique phase of matter.

The Luttinger-Ward functional approach in the Eliashberg framework: a systematic derivation of scaling for thermodynamics near the quantum critical point.

Scaling expressions for the free energy are derived, using the Luttinger-Ward (LW) functional approach in the Eliashberg framework, for two different models of the quantum critical point (QCP). First, we consider the spin-density-wave model for which the effective theory is the Hertz-Moriya-Millis theory, describing the interaction between itinerant electrons and collective spin fluctuations. The dynamics of the latter are described using a dynamical exponent z depending on the nature of the transition. Second, we consider the Kondo breakdown model for QCPs, one possible scenario for heavy-fermion quantum transitions, for which the effective theory is given by a gauge theory in terms of conduction electrons, spinons for localized spins, holons for hybridization fluctuations, and gauge bosons for collective spin excitations. For both models, we construct the thermodynamic potential, in the whole phase diagram, including all kinds of self-energy corrections in a self-consistent way, at the one-loop level. We show how the Eliashberg framework emerges at this level and use the resulting Eliashberg equations to simplify the LW expression for the free energy. It is found that collective boson excitations play a central role. The scaling expression for the singular part of the free energy near the Kondo breakdown QCP is characterized by two length scales: one is the correlation length for hybridization fluctuations, and the other is that for gauge fluctuations, analogous to the penetration depth for superconductors.

Quantum Boltzmann equation study for the Kondo breakdown quantum critical point.

We develop the quantum Boltzmann equation approach for the Kondo breakdown quantum critical point, involved with two bands for conduction electrons and localized fermions. Particularly, the role of vertex corrections in transport is addressed, crucial for non-Fermi liquid transport with temperature linear dependence. Only one band of spinons may be considered for scattering with gauge fluctuations, and their associated vertex corrections are introduced in the usual way, where the divergence of self-energy corrections is cancelled by that of vertex corrections, giving rise to a physically meaningful result in the gauge invariant expression for conductivity. On the other hand, two bands should be taken into account for scattering with hybridization excitations, giving rise to coupled quantum Boltzmann equations. We find that vertex corrections associated with hybridization fluctuations turn out to be irrelevant due to the heavy mass of spinons in the so called decoupling limit, consistent with the diagrammatic approach showing non-Fermi liquid transport.

Exact bosonization for an interacting fermi gas in arbitrary dimensions.

We present an exact mapping of models of interacting fermions onto boson models. The bosons correspond to collective excitations in the initial fermionic models. This bosonization is applicable in any dimension and for any interaction between fermions. Introducing superfields, we derive a field theory that may serve as a new way of analytical study. We show schematically how the mapping can be used for Monte Carlo calculations and argue that it should be free from the sign problem.

Violation of the Wiedemann-Franz law at the Kondo breakdown quantum critical point.

We study the electrical and thermal transport near the heavy-fermion quantum critical point, identified with the breakdown of the Kondo effect. We show that the electrical conductivity comes mainly from conduction electrons while the thermal conductivity is given by both conduction electrons and localized fermions (spinons), scattered with hybridization fluctuations of dynamical exponent z = 3. As a result, we reveal that not only electrical but also thermal resistivity displays quasilinear temperature dependence in the intermediate temperature range, the main prediction of our transport study. An important feature turns out to be emergence of additional entropy carriers, that is, spinon excitations. We find that the Wiedemann-Franz ratio should be larger than the standard value, differentiating the Kondo breakdown scenario from the Hertz-Moriya-Millis framework.

Amphiphilic perfluoroalkyl carbohydrates as new tools for liver imaging.

The synthesis of three molecules containing a fluorocarbon chain (either C(6)F(13), C(8)F(17) or C(10)F(21)), a sugar moiety (derived from lactobionic acid) and a chelate (derived from DTPA) is reported. These molecules (C(6)F(13)-Gal-DTPA, C(8)F(17)-Gal-DTPA or C(10)F(21)-Gal-DTPA) have been dispersed in water and their critical micellar concentration (CMC) as well as their size were determined. Their interaction with serum was weak as evaluated by time resolved fluorimetry of europium complexes. The presence of sugar on the surface of the nanoparticles was confirmed by the agglutination test using ricin. Conditions of pH and concentrations were optimised for in vivo studies. Finally, the nanoparticles formed with C(10)F(21)-Gal-DTPA have been complexed with (99m)Tc and injected to rats in order to follow their biodistribution by scintigraphy while following their stability by transmission electronic microscopy. A majority of the compound was found in the liver post-bolus injection.

Grüneisen ratio at the kondo-breakdown quantum critical point.

We show that the scenario of a multiscale Kondo-breakdown quantum critical point gives rise to a divergent Grüneisen ratio with an anomalous exponent 0.7. In particular, we fit the experimental data of YbRh2(Si0.95Ge0.05)2 for a specific heat, thermal expansion, and Grüneisen ratio based on our simple analytic expressions. A reasonable agreement between the experiment and theory is found for the temperature range between 0.4 and 10 K. We discuss how the Grüneisen ratio is a key measurement to discriminate between the Kondo-breakdown and spin-density wave theories.

Model of quantum criticality in He3 bilayers adsorbed on graphite.

Recent experiments on He3 bilayers adsorbed on graphite have shown striking quantum critical properties at the point where the first layer localizes. We model this system with the Anderson lattice plus interlayer Coulomb repulsion in two dimensions. Assuming that quantum critical fluctuations come from a vanishing of the effective hybridization, we can reproduce several features of the system, including the apparent occurrence of two quantum critical points, the variation of the effective mass and coherence temperature with coverage.

Sci-Sat AM(1): Imaging-08: Small animal APD PET detector with submillimetric resolution for molecular imaging.

Visualization and quantification of biological processes in mice, the preferred animal model in most preclinical studies, require the best possible spatial resolution in positron emission tomography (PET). A new 64-channel avalanche photodiode (APD) detector module was developed to achieve submillimeter spatial resolution for this purpose. The module consists of dual 4 × 8 APD arrays mounted in a custom ceramic holder. Individual APD pixels having an active area of 1.1 × 1.1 mm2 at a 1.2 mm pitch can be fitted to an 8 × 8 LYSO scintillator block designed to accommodate one-to-one coupling. An analog test board with four 16-channel preamplifier ASICs was designed to be interfaced with the existing LabPET digital processing electronics. At a standard APD operating bias, a mean energy resolution of 27.5 ± 0.6% was typically obtained at 511 keV with a relative standard deviation of 13.8% in signal amplitude for the 64 individual pixels. Crosstalk between pixels was found to be well below the typical lower energy threshold used for PET imaging applications. With two modules in coincidence, a global timing resolution of 5.0 ns FWHM was measured. Finally, an intrinsic spatial resolution of 0.8 mm FWHM was measured by sweeping a 22Na point source between two detector arrays. The proposed detector module demonstrates promising characteristics for dedicated mouse PET imaging at submillimiter resolution.