ABSTRACT
BACKGROUND: Few studies have assessed health-related quality of life (HRQoL) among patients undergoing cholecystectomy. This study aimed to determine clinical variables that predict changes in HRQoL following cholecystectomy. METHODS: This was a prospective study of consecutive patients undergoing elective cholecystectomy for gallstones in six hospitals. Patients were asked to complete two questionnaires-the Short Form 36 (SF-36) and the Gastrointestinal Quality of Life Index (GIQLI)-before and 3 months after cholecystectomy. Multivariate linear regression models were used to examine factors potentially contributing to changes in HRQoL. RESULTS: Patients with symptomatic cholelithiasis and low surgical risk experienced the highest HRQoL gains in several SF-36 and GIQLI domains, with significant improvements in physical function detected by both instruments, compared with asymptomatic individuals at high surgical risk. Patients with asymptomatic cholelithiasis or high surgical risk experienced least improvement. CONCLUSION: These data indicate that cholecystectomy is appropriate for patients with symptomatic cholelithiasis and low surgical risk. In terms of HRQoL, the risk to benefit ratio seems poor for patients with asymptomatic gallstones.
Subject(s)
Cholecystectomy/psychology , Cholelithiasis/surgery , Quality of Life , Surveys and Questionnaires/standards , Aged , Analysis of Variance , Cholelithiasis/psychology , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Prospective Studies , Regression Analysis , Risk Factors , Sensitivity and SpecificityABSTRACT
Objetivo: traducir al español y validar el GIQLI, un cuestionario de medición de calidad de vida relacionada con la salud para patología gastrointestinal Pacientes y métodos: en el estudio se incluyen todos los pacientes con diagnóstico de colelitiasis, en lista de espera para ser intervenidos de colecistectomía, en tres hospitales públicos. A todos los pacientes se les pidió que cumplimentaran los cuestionarios GIQLI y SF-36 antes de la intervención y a los 3 meses de la misma. Se estudió la validez, fiabilidad y sensibilidad al cambio del GIQLI. Resultados: completaron ambos cuestionarios, antes y después de la colecistectomía, 353 pacientes. El GIQLI fue capaz de detectar diferencias según nivel de gravedad, medido por el número de cólicos previos, entre aquéllos con menos de 6 cólicos (puntuación total del GIQLI: 102,7) o más de 6 (89,2). Las áreas del GIQLI correlacionaron bien con el SF-36 (coeficiente de correlación de Pearson de 0,58 a 0,79). La consistencia interna de sus áreas fue buena ( de Cronbach de 0,70 a 0,86). La sensibilidad al cambio, medida por la media de respuesta estandarizada, de las áreas del GIQLI fue de 0,45 a 0,82, mejor que la del cuestionario genérico SF-36 (0,20 a 0,56).Conclusiones: la traducción de GIQLI al español proporciona una nueva herramienta de medición de la cálida de vida, para su uso en patología gastrointestinal. Nuestros resultados apoyan la validez, fiabilidad y sensibilidad al cambio de este cuestionario (AU)
Subject(s)
Middle Aged , Male , Female , Humans , Quality of Life , Health Status Indicators , Translations , Surveys and Questionnaires , Cholelithiasis , Gastrointestinal Diseases , Follow-Up StudiesABSTRACT
OBJECTIVE: To translate into Spanish and validate the GIQLI, a health related quality of life questionnaire for gastrointestinal diseases. PATIENTS AND METHODS: All patients with a diagnosis of cholelithiasis, on waiting list to undergo a cholecystectomy, from three public hospitals, were included in this study. All patients were requested to fulfill the GIQLI and the SF-36 before and three months after the intervention. The validity, reliability and responsiveness of the GIQLI were studied. RESULTS: 353 patients completed both questionnaires before and after the intervention. The GIQLI was able to discriminate among levels of severity, measured by the number of previous biliary colics, between those with less (total GIQLI score: 102.7) or more than 6 colics (89.2). GIQLI domains correlated with those of the SF-36 (Pearson correlation coefficient from 0.58 to 0.79). Internal consistency of its domains was good (Cronbach alpha from 0.70 to 0.86). Responsiveness, measured by the standardized response mean, of the GIQLI ranged between 0.45 to 0.82, better than the generic questionnaire SF-36 (0.20 a 0.56). CONCLUSIONS: GIQLI translation into Spanish provides with a new tool to measure quality of life on gastrointestinal diseases. Our results support the validity, reliability and responsiveness of the GIQLI Spanish version.
