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Rev. psiquiatr. infanto-juv ; 30(1): 72-76, ene.-mar. 2013.
Article in Spanish | IBECS | ID: ibc-113064

ABSTRACT

El síndrome de Klinefelter (47XXY) es una aneuploidía cromosómica caracterizada por alteraciones metabólicas y hormonales secundarias fundamentalmente al déficit de testosterona que presentan estos individuos desde la infancia. Asimismo, los niños y adolescentes con este tipo de trastorno presentan un riesgo incrementado de padecer patología de corte afectivo, presumiblemente relacionada con el cuadro de adaptación y también con el propio déficit hormonal. Con el objetivo de paliar la sintomatología depresiva, se han empleado medidas convencionales que incluyen el tratamiento psicofarmacológico y psicoterapéutico. En adultos deprimidos con déficit de testosterona se ha empleado dicha hormona de forma exitosa. El propósito de este caso clínico es recoger la evolución de los síntomas depresivos en un adolescente con Klinefelter que recibió tratamiento psicoterapéutico y hormonal con testosterona (AU)


Klinefelter syndrome (47, XXY) is the most common sex chromosome aneuploidy in males. Principal effects include metabolic and endocrine disorders related to testosterone deiciency. Although not all males develop the characteristic symptoms of Klinefelter syndrome, testosterone deiciency is present in all of them. An increased incidence of anxiety and depression is reported in boys and adolescents with 47, XXY. Depressive symptoms have been associated to testosterone deiciency and also as an adaptive reaction to disease. Psychiatric treatment of depression in patients with Klinefelter syndrome has been limited to drug therapy and supportive psychotherapy. However, studies suggest that testosterone replacement may have an antidepressant effect in depressed adults with testosterone deiciency. The purpose of this case study is to report the course of depressive symptoms in an adolescent subject with Klinefelter syndrome treated with testosterone and psychotherapy (AU)


Subject(s)
Humans , Male , Adolescent , Klinefelter Syndrome/complications , Depressive Disorder/etiology , Testosterone/deficiency , Testosterone/therapeutic use , Psychotherapy
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