Subject(s)
Histiocytosis, Langerhans-Cell/complications , Osteitis/diagnostic imaging , Osteolysis/diagnostic imaging , Staphylococcal Infections/diagnostic imaging , Zygoma/diagnostic imaging , Child , Female , Histiocytosis, Langerhans-Cell/diagnostic imaging , Humans , Organotechnetium Compounds/pharmacokinetics , Osteitis/etiology , Osteitis/microbiology , Osteolysis/etiology , Peptide Fragments/pharmacokinetics , Radionuclide Imaging , Radiopharmaceuticals/pharmacokinetics , Ribosomal Proteins/pharmacokinetics , Staphylococcal Infections/etiology , Tomography, X-Ray ComputedABSTRACT
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Subject(s)
Humans , Female , Child , Histiocytosis, Langerhans-Cell/complications , Osteitis , Osteolysis , Radiopharmaceuticals/pharmacokinetics , Staphylococcal Infections , Tomography, X-Ray Computed , Zygoma , Zygoma , Histiocytosis, Langerhans-Cell , Organotechnetium Compounds/pharmacokinetics , Osteitis/etiology , Osteitis/microbiology , Osteitis , Osteolysis/etiology , Osteolysis , Peptide Fragments/pharmacokinetics , Staphylococcal Infections/etiology , Staphylococcal InfectionsABSTRACT
UNLABELLED: This work aimed to assess the utility of 99mTc-MIBI scintigraphy in the diagnosis and follow-up of lymphoma patients. Seventy-two patients with a previous diagnosis of lymphoma (41 with Hodgkin's and 31 with non-Hodgkin's disease) and a control group of 8 patients with palpable lymph nodes and a negative diagnosis of lymphoma based on the clinical examination, chest x-ray, lymphography, ultrasounds and biopsy were studied. Whole body scintigraphies were performed 20 min and 2 h after i.v. administration of 740 MBq of 99mTc-MIBI. The joint result of the already mentioned standard diagnostic tests was considered as the confirmation criterion. A sensitivity, specificity and accuracy of 96,2%, 100% and 97,4% respectively were obtained. Kappa coefficient was k = 0,94 +/- 0,11. CONCLUSION: Scintigraphy with 99mTc-MIBI is a useful tool for the diagnosis and follow-up of lymphomas regardless of their classification.
Subject(s)
Hodgkin Disease/diagnostic imaging , Lymphoma, Non-Hodgkin/diagnostic imaging , Technetium Tc 99m Sestamibi , Adolescent , Adult , Aged , Castleman Disease/diagnostic imaging , Child , Child, Preschool , Evaluation Studies as Topic , Female , Follow-Up Studies , Humans , Lymphadenitis/diagnostic imaging , Male , Middle Aged , Radionuclide Imaging , Sensitivity and SpecificityABSTRACT
El objetivo del presente trabajo fue evaluar la utilidad de la gammagrafía con 99mTc-metoxi-isobutil-isonitrilo (MIBI) en el diagnóstico y seguimiento de pacientes que padecen de linfoma. Se estudiaron 72 pacientes con diagnóstico de linfoma (41 Hodgkin y 31 no Hodgkin) y un grupo control de 8 pacientes con ganglios palpables y diagnóstico negativo de linfoma producto de la evaluación clínica, radiografía de tórax, linfografía, ultrasonido y la biopsia. Se realizaron rastreos gammagráficos 20 min y 2 h después de la administración i.v. de 740 MBq de 99mTc-MIBI. El resultado conjunto de los instrumentos diagnósticos antes señalados se tomó como criterio de confirmación. Se obtuvo una sensibilidad, especificidad y exactitud de 96,2 per cent, 100 per cent y 97,4 per cent respectivamente. El coeficiente Kappa fue de 0,94 ñ 0,11. Conclusión: La gammagrafía con 99mTc-MIBI es útil para el diagnóstico y seguimiento de los linfomas, independientemente de su clasificación (AU)
