Understanding belief in political statements using a model-driven experimental approach: a registered report.

Misinformation harms society by affecting citizens' beliefs and behaviour. Recent research has shown that partisanship and cognitive reflection (i.e. engaging in analytical thinking) play key roles in the acceptance of misinformation. However, the relative importance of these factors remains a topic of ongoing debate. In this registered study, we tested four hypotheses on the relationship between each factor and the belief in statements made by Argentine politicians. Participants (N = 1353) classified fact-checked political statements as true or false, completed a cognitive reflection test, and reported their voting preferences. Using Signal Detection Theory and Bayesian modeling, we found a reliable positive association between political concordance and overall belief in a statement (median = 0.663, CI95 = [0.640, 0.685]), a reliable positive association between cognitive reflection and scepticism (median = 0.039, CI95 = [0.006, 0.072]), a positive but unreliable association between cognitive reflection and truth discernment (median = 0.016, CI95 = [- 0.015, 0.046]) and a negative but unreliable association between cognitive reflection and partisan bias (median = - 0.016, CI95 = [- 0.037, 0.006]). Our results highlight the need to further investigate the relationship between cognitive reflection and partisanship in different contexts and formats. PROTOCOL REGISTRATION: The stage 1 protocol for this Registered Report was accepted in principle on 22 August 2022. The protocol, as accepted by the journal, can be found at: https://doi.org/10.17605/OSF.IO/EBRGC .

Background music changes the policy of human decision-making: Evidence from experimental and drift-diffusion model-based approaches on different decision tasks.

Music is ubiquitous in our lives. Although we listen to music as an activity in and of itself, music is frequently played while we are engaged in other activities that rely on decision-making (e.g., driving). Despite its ubiquity, it remains unknown whether and how background music modulates the speed and accuracy of decision-making across different domains. We hypothesized that music could affect decision-making through a subjective-timing distortion or via a policy shift toward less-cautious responding. We analyzed response times and accuracy from more than 100-thousand decisions and mapped the effects of music onto decision-process components with a mechanistic model of decision-making. We found evidence supporting the latter hypothesis, by which decisions-across domains-were faster but less accurate with music, and this trade-off was mainly driven by a less conservative decision policy. Overall, our results suggest that background music shapes our decisions by making us less cautious. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Learning-by-Teaching Approach Improves Dengue Knowledge in Children and Parents.

There is narrow evidence on which strategies are most effective for disseminating information on dengue prevention. This is particularly relevant because social habits have a great prevention capacity for dengue. We investigated how effective are children as health educators, and how much they learn as they teach. We recruited 142 children and 97 parents in Argentina's tropical area for two cluster randomized parallel trials. In Study 1, we compared the dynamics of dengue knowledge of 10-year-old children who-after receiving a dengue talk-1) listened to an unrelated topic; 2) read a booklet with information about dengue, 3) taught their parents about dengue, or 4) taught their parents about dengue, using the booklet. In Study 2, we assessed whether the parents' dengue knowledge changed after interacting with their children, in comparison with parents learning about dengue from an expert or about an unrelated topic. Children that taught their parents what they learned, using a booklet, showed 2.53 more correct responses (95% CI [0.20, 4.85]; P = 0.027) than children who listened to an unrelated topic. This style of teaching also serves to effectively propagate knowledge: parents learned from their children the same as from an expert; and significantly more than parents who learned about an unrelated topic. Parents learned from their children even if they were taught with booklets (1.49, 95% CI [0.01, 2.96]; P = 0.048) or without (1.94, 95% CI [0.44, 3.44]; P = 0.006). Specifically, after being taught by their children, parents showed on average 1.49 (if they were taught with a booklet) and 1.94 (without booklet) more correct responses than parents that learned about an unrelated topic. The simple action of prompting children to teach consolidated their own knowledge and broadcasted it effectively to their parents. This strategy is a potential low to no-cost method for sharing information about dengue prevention.

Using long ssDNA polynucleotides to amplify STRs loci in degraded DNA samples.

Obtaining informative short tandem repeat (STR) profiles from degraded DNA samples is a challenging task usually undermined by locus or allele dropouts and peak-high imbalances observed in capillary electrophoresis (CE) electropherograms, especially for those markers with large amplicon sizes. We hereby show that the current STR assays may be greatly improved for the detection of genetic markers in degraded DNA samples by using long single stranded DNA polynucleotides (ssDNA polynucleotides) as surrogates for PCR primers. These long primers allow a closer annealing to the repeat sequences, thereby reducing the length of the template required for the amplification in fragmented DNA samples, while at the same time rendering amplicons of larger sizes suitable for multiplex assays. We also demonstrate that the annealing of long ssDNA polynucleotides does not need to be fully complementary in the 5' region of the primers, thus allowing for the design of practically any long primer sequence for developing new multiplex assays. Furthermore, genotyping of intact DNA samples could also benefit from utilizing long primers since their close annealing to the target STR sequences may overcome wrong profiling generated by insertions/deletions present between the STR region and the annealing site of the primers. Additionally, long ssDNA polynucleotides might be utilized in multiplex PCR assays for other types of degraded or fragmented DNA, e.g. circulating, cell-free DNA (ccfDNA).

Circadian period integrates network information through activation of the BMP signaling pathway.

Living organisms use biological clocks to maintain their internal temporal order and anticipate daily environmental changes. In Drosophila, circadian regulation of locomotor behavior is controlled by ∼150 neurons; among them, neurons expressing the PIGMENT DISPERSING FACTOR (PDF) set the period of locomotor behavior under free-running conditions. To date, it remains unclear how individual circadian clusters integrate their activity to assemble a distinctive behavioral output. Here we show that the BONE MORPHOGENETIC PROTEIN (BMP) signaling pathway plays a crucial role in setting the circadian period in PDF neurons in the adult brain. Acute deregulation of BMP signaling causes period lengthening through regulation of dClock transcription, providing evidence for a novel function of this pathway in the adult brain. We propose that coherence in the circadian network arises from integration in PDF neurons of both the pace of the cell-autonomous molecular clock and information derived from circadian-relevant neurons through release of BMP ligands.