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Developments in high-throughput functional epigenomics: CRISPR-single-cell assay for transposase-accessible chromatin using sequencing screens.
E Yan, Rachel; P Greenfield, Jeffrey; Dahmane, Nadia.
Epigenomics ; 14(11): 645-649, 2022 06.
Article in English | MEDLINE | ID: mdl-35574596

ABSTRACT

Tweetable abstract CRISPR-scATAC-seq screens pave the way for high-throughput functional epigenomics by linking perturbations to a broad view of epigenetic state and messages hidden within accessible sequences.


Subject(s)
Chromatin , Epigenomics , Chromatin/genetics , Chromatin Immunoprecipitation Sequencing , Clustered Regularly Interspaced Short Palindromic Repeats , High-Throughput Nucleotide Sequencing , Humans , Sequence Analysis, DNA , Transposases/genetics , Transposases/metabolism
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