Comparison of the effect of conventional and implant-retained overdentures on brain activity and cognition in a geriatric population - A functional MRI study.

PURPOSE: This study aims to evaluate the effect of rehabilitation with complete dentures versus implant-retained overdenture on activity in various parts of the brain cognition in a geriatric edentulous population via Functional MRI (fMRI) studies and the Mini-Mental State Examination (MMSE). METHODS: Ten completely edentulous patients were rehabilitated with both complete dentures and two-implant retained overdentures for three months each. fMRI studies were performed for each modality during chewing and recall tasks at three time periods: T0: Completely Edentulous (CE) T1: after three months of wearing Conventional Complete Dentures (CD) and T2: after three months of wearing Implant-retained Overdentures (IOD). The Z scores obtained from the fMRI at these phases of examination were tabulated and correlated with MMSE scores obtained at the corresponding time periods. RESULTS: Z scores obtained during the memory recall tasks at T2 were the greatest (Prefrontal Cortex (p=0.059) and Hippocampus (p=0.036). The MMSE scores obtained were significantly higher for the IODs when compared to the CDs and Baseline values (p < 0.05). CONCLUSION: IODs may potentially result in superior sensory feedback in edentulous patients and lead to improved cognitive performance when compared to conventional complete dentures.

Incidence of neurosensory disturbance in mandibular implant surgery - A meta-analysis.

AIM: Implantology has been widely accepted as the mainstay treatment for rehabilitating complete and partial edentulism. However, it is associated with some failures and complications, the most concerning being neurosensory disturbance. Although neurosensory disturbance has been extensively studied, the incidence and cause remains largely variable. Thus, the aim of this systematic review and meta-analysis was to evaluate the incidence, distribution, and recovery rate of neurosensory disturbance. SETTINGS AND DESIGN: This systematic review was conducted as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement. A structured literature review was conducted using the following databases: PubMed, Science Direct, Cochrane, Ovid, and Google Scholar for reports related to neurosensory disturbance experienced after implant placement in the mandible. STATISTICAL ANALYSIS USED: Incidence and recovery rate for 100 person-years was calculated using the Poisson regression model. The risk difference of incidence between anterior and posterior implants was calculated with a random effects model. RESULTS: Electronic database search yielded 1589 articles; a total of nine articles were selected for the meta-analysis. The risk of neurosensory disturbance was estimated at 13.50/100 person-years (95% confidence interval (CI): 10.98-16.03), with a greater risk with anteriorly placed implants: -0.02 (95% CI: -0.21-0.16) (P = 0.05). The overall recovery rate was estimated at 51.30/100 person-years (95% CI: 31.2-71.4). CONCLUSIONS: Within the limitations of the study, it can be concluded that mandibular implant placement is associated with a considerable risk of neurosensory disturbance. A large proportion of these patients present with spontaneous recovery; however, clinicians must take necessary precautions to avoid such complications. More randomized controlled trials are required to quantify the effect of factors leading to altered sensation during implant placement.

Single Implant Retained Overdenture Treatment Protocol: A Systematic Review and Meta-Analysis.

PURPOSE: This systematic review was undertaken to establish the most favourable protocol to treat an edentulous mandible with a single implant-retained overdenture. The formulated PICO question was: "Which surgical and prosthetic protocols result in the highest survival and complication rates of implants and prostheses employed in a single implant retained overdenture for the rehabilitation of a completely edentulous mandibular ridge?" MATERIALS AND METHODS: A structured literature search was conducted using the following databases; PubMed, ScienceDirect, COCHRANE, LILACS, IndeMED, OVID, EMBASE, NIH Clinical Trials for reports related to the single implant-retained overdenture treatment. Only English articles were included. Publications with a minimum follow up time of 1 year and above were included for meta-analysis. A Poisson regression model was applied to estimate the survival rates of the implant and prosthesis employed. RESULTS: The electronic database search yielded 2083 titles and abstracts; and a total of 17 were selected for the systematic review, of which 11 studies were subjected to meta-analysis. The implants showed high estimated five and 10-year survival rates of 91.93% and 84.62%, respectively. Implants that were delayed loaded showed the greatest survival rates, while immediately loaded implants presented with higher survival rates at five (p = 0.849) and 10 years (p = 0.464) when compared to early loaded implants. The greatest number of fractures were associated with ball abutments with an event rate of 10.8 (95% CI: 10.5-11.09) per 100 prosthesis years, while locator abutments showed a greater number of maintenance events with an event rate of 16.84(95% CI:16.01-17.66) per 100 prosthesis years. CONCLUSION: Single implant-retained overdenture treatment is a cost-effective, minimally invasive and simple treatment that can be used to restore function and aesthetics to edentulous patients, with relatively high implant and prosthesis success rates and minimal complications.