ABSTRACT
The influence of a 50 Hz magnetic field (MF) on avian and mammalian embryogenesis, the MF level and vector, as well as the effect of exposure to MF (50 Hz, 10 mT) in combination with X-rays has been recently reported [2,3]. No significant alterations of chick or rat embryogenesis were found after repeated exposures to 50 Hz MF at 10 mT or 6 microT or with different vectors. However, X-ray chick embryotoxicity was significantly affected by repeated exposures of developing organisms to MF. A strong dependence of effect on the type of interaction was revealed. A decrease of X-ray induced teratogenicity was observed when MF preceded X-ray exposure (indirect interaction), while MF exposure applied immediately after X-ray radiation (direct interaction) non-significantly potentiated adverse developmental effects of ionizing radiation. This study deals with the effects of MF in combination with insulin or tetracycline. Exposure of chick embryos to MF influenced the sensitivity of embryonic morphogenetic systems to the subsequently administered chemical teratogens, insulin and/or tetracycline. A protective effect of MF was detected similarly as in the case of indirect interaction with ionizing radiation.
Subject(s)
Abnormalities, Drug-Induced/prevention & control , Chick Embryo/drug effects , Chick Embryo/radiation effects , Electromagnetic Fields/adverse effects , Teratogens/toxicity , Animals , Chick Embryo/abnormalities , Insulin/toxicity , Tetracycline/toxicity , X-Rays/adverse effectsABSTRACT
We studied the influence of power frequency and vector of EMF on avian and mammalian embryogenesis at a high level of magnetic induction (10 mT professional exposures and using therapeutic devices of Czech provenance) and at a low level (6 microT-environmental occurrence). No significant alterations of either avian or mammalian embryogenesis were found after repeated exposures to 50 Hz MF at 10 mT or 6 microT, nor with different vectors.
Subject(s)
Electromagnetic Fields , Embryonic and Fetal Development/radiation effects , Animals , Chick Embryo/radiation effects , Environmental Exposure , RatsABSTRACT
We studied the combined effects of exposure to magnetic field (MF) 50 Hz 10 mT and X-ray ionizing radiation on developing chick embryos. When chick embryos at early stages were repeatedly exposed to MF prior to X-ray radiation, reduction of X-ray teratogenicity was observed. When MF exposures started immediately after X-ray radiation, the adverse developmental effects of ionizing radiation were potentiated. Embryotoxicity was more pronounced in X-ray irradiated and MF exposed groups. We present a hypothesis about the mechanisms of MF effect based on enhancement of oxidative processes, followed by stimulation of antioxidant systems.
