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1.
Wound Repair Regen ; 32(1): 6-33, 2024.
Article in English | MEDLINE | ID: mdl-37970711

ABSTRACT

The major populations at risk for developing pressure ulcers are older adults who have multiple risk factors that increase their vulnerability, people who are critically ill and those with spinal cord injury/disease. The reported prevalence of pressure ulcers in the United States is 2.5 million. However, this estimate is derived from acute care facilities and does not include people who are living at home or in nursing facilities. Despite the implementation of hospital and facility-based preventive measures, the incidence of pressure ulcers has not decreased in decades. In addition to the burden of pain, infection and death, it is estimated that hospital-acquired pressure ulcers cost the health system $26.8 billion annually with over 50% of the cost attributed to treating Stage 3 and 4 pressure injuries. Thus, it is critical to examine the literature and develop guidelines that will improve the outcomes of this complex and costly condition. This guideline update is a compendium of the best available evidence for the treatment of Pressure Ulcers published since the last update in 2015 and includes a new section based on changing demographics entitled 'Palliative wound care for seriously ill patients with pressure ulcers'. The overall goal of the Wound Healing Society Guideline project is to present clear, concise and commercial free guidelines that clinicians can use to guide care, that researchers can use to develop studies that will improve treatment and that both clinicians and researchers can use to understand the gaps in our knowledge base.


Subject(s)
Pressure Ulcer , Humans , Aged , Pressure Ulcer/epidemiology , Pressure Ulcer/therapy , Pressure Ulcer/etiology , Wound Healing , Risk Factors , Prevalence
2.
Cureus ; 14(10): e30437, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36407233

ABSTRACT

Holospinal epidural abscess (HEA) is an extremely rare spinal infection involving the entire spine and is infrequently reported in the literature. Cases with evidence of spinal cord compression and consequent neurological deficit are typically managed with prompt surgical drainage and broad-spectrum antibiotics. Surgical intervention is often challenging because this condition is inherently associated with poor prognosis and serious complications, including death. During the surgical evacuation of the abscess, catheter-based irrigation must be adequately performed. In the majority of reported cases, the extent of the advancement of the epidural catheter is blindly assessed by the operating surgeon, increasing the risk of residual collections and subsequent persistent infection. Herein, we report a rare case of HEA that was successfully treated with surgical evacuation and skip laminectomies. We also describe a catheter-based technique that facilitates adequate irrigation, thereby ensuring the complete drainage of HEA in obscured perispinal areas, as well as the decompression of the spinal cord. Postoperative neurological examination exhibited marked improvement in motor function (compared with a baseline of complete quadriparesis), indicating the successful decompression of the spinal cord and neurological improvement.

3.
Cureus ; 9(8): e1619, 2017 Aug 28.
Article in English | MEDLINE | ID: mdl-29098129

ABSTRACT

This case report discusses the rare issue of an atrophic cervical pedicle at the C6 level in a patient found unconscious with a jumped facet and an unknown mechanism of injury. A means to discern between traumatic jumped facets versus congenital anomalies is addressed, including missing pedicles, which is encountered at the C6 level in this case. A literature review revealed that the most common level where this occurs is at the C6 level. The structural anatomic pathologies and the variants relative to congenital facet atrophy are identified, including the location and the surrounding vasculature; more specifically, the vertebral arteries. This information is helpful to assist clinicians when discerning between a traumatic subluxation injury that requires instrumentation and reduction versus a congenital anomaly that can usually be managed conservatively.

4.
Clin Spine Surg ; 30(7): E988-E992, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28452795

ABSTRACT

STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The objective of this study is to compare the incidence of infection in patients who do and do not receive blood transfusions in major deformity surgery (>8 levels). SUMMARY OF BACKGROUND DATA: Postoperative infections increase morbidity and mortality rates in spine surgery and generate additional costs for the health care system. It has been proposed that blood transfusions increase the risk of wound infection, urinary tract infection, pneumonia, and sepsis. METHODS: A total of 56 patients met the study criteria, receiving spine surgery involving the fusion of 8 levels or more. Patient-specific characteristics, starting and ending hematocrits, number of units transfused and infections including urinary tract infection, wound infection, pneumonia, and sepsis were documented. Differences in infection risk between those who did and did not undergo a transfusion and their 95% confidence intervals were calculated. RESULTS: Groups were similar with respect to baseline and surgical characteristics except for smoking status, operative time, estimated blood loss, and ending hematocrit. The overall infection rate was greater in patients who underwent transfusion than those who did not (36% vs. 10%; P=0.03). Wound infections (n=5) were only observed in those who underwent a transfusion. Smokers were more likely to receive a transfusion and more likely to experience infection. A stratified analysis demonstrated an increased risk of infection associated with transfusion; however, the risk was greater in smokers, suggesting the effect of transfusion on infection could be modified by smoking. Patients undergoing transfusion experienced a significantly longer hospital stay (P=0.01). CONCLUSIONS: Allogeneic red blood cell transfusion in major spine surgery could be a risk factor for postoperative infection. This increased risk seems to be magnified in those who smoke. Further studies are warranted, and risks of blood loss and transfusion-related complications in smokers also potentially merit exploration. LEVEL OF EVIDENCE: Level 3.


Subject(s)
Blood Transfusion , Orthopedic Procedures/adverse effects , Spine/surgery , Surgical Wound Infection/etiology , Transfusion Reaction/etiology , Aged , Confounding Factors, Epidemiologic , Female , Humans , Length of Stay , Male , Middle Aged , Risk Factors , Smoking/adverse effects , Treatment Outcome
5.
Cureus ; 9(2): e1032, 2017 Feb 16.
Article in English | MEDLINE | ID: mdl-28357164

ABSTRACT

Spinal hematomas are a rare but serious complication of spinal epidural anesthesia and are typically seen in the epidural space; however, they have been documented in the subdural space. Spinal subdural hematomas likely exist within a traumatically induced space within the dural border cell layer, rather than an anatomical subdural space. Spinal subdural hematomas present a dangerous clinical situation as they have the potential to cause significant compression of neural elements and can be easily mistaken for spinal epidural hematomas. Ultrasound can be an effective modality to diagnose subdural hematoma when no epidural blood is visualized. We have reviewed the literature and present a full literature review and a case presentation of an 82-year-old male who developed a thoracolumbar spinal subdural hematoma after spinal epidural anesthesia. Anticoagulant therapy is an important predisposing risk factor for spinal epidural hematomas and likely also predispose to spinal subdural hematomas. It is important to consider spinal subdural hematomas in addition to spinal epidural hematomas in patients who develop weakness after spinal epidural anesthesia, especially in patients who have received anticoagulation.

6.
J Neurosurg Spine ; 26(6): 679-683, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28304240

ABSTRACT

OBJECTIVE Posterior atlantoaxial stabilization and fusion using C-1 lateral mass screw fixation has become commonly used in the treatment of instability and for reconstructive indications since its introduction by Goel and Laheri in 1994 and modification by Harms in 2001. Placement of such lateral mass screws can be challenging because of the proximity to the spinal cord, vertebral artery, an extensive venous plexus, and the C-2 nerve root, which overlies the designated starting point on the posterior center of the lateral mass. An alternative posterior access point starting on the posterior arch of C-1 could provide a C-2 nerve root-sparing starting point for screw placement, with the potential benefit of greater directional control and simpler trajectory. The authors present a cadaveric study comparing an alternative strategy (i.e., a C-1 screw with a posterior arch starting point) to the conventional strategy (i.e., using the lower lateral mass entry site), specifically assessing the safety of screw placement to preserve the C-2 nerve root. METHODS Five US-trained spine fellows instrumented 17 fresh human cadaveric heads using the Goel/Harms C-1 lateral mass (GHLM) technique on the left and the posterior arch lateral mass (PALM) technique on the right, under fluoroscopic guidance. After screw placement, a CT scan was obtained on each specimen to assess for radiographic screw placement accuracy. Four faculty spine surgeons, blinded to the surgeon who instrumented the cadaver, independently graded the quality of screw placement using a modified Upendra classification. RESULTS Of the 17 specimens, the C-2 nerve root was anatomically impinged in 13 (76.5%) of the specimens. The GHLM technique was graded Type 1 or 2, which is considered "acceptable," in 12 specimens (70.6%), and graded Type 3 or 4 ("unacceptable") in 5 specimens (29.4%). In contrast, the PALM technique had 17 (100%) of 17 graded Type 1 or 2 (p = 0.015). There were no vertebral artery injuries found in either technique. All screw violations occurred in the medial direction. CONCLUSIONS The PALM technique showed statistically fewer medial penetrations than the GHLM technique in this study. The reason for this is not clear, but may stem from a more angulated "up-and-in" screw direction necessary with a lower starting point.


Subject(s)
Bone Screws , Cervical Vertebrae/surgery , Spinal Fusion/methods , Aged , Atlanto-Axial Joint/diagnostic imaging , Atlanto-Axial Joint/surgery , Cadaver , Cervical Vertebrae/diagnostic imaging , Female , Humans , Male , Postoperative Complications/prevention & control , Spinal Fusion/adverse effects , Spinal Fusion/instrumentation , Spinal Nerve Roots/diagnostic imaging , Spinal Nerve Roots/injuries , Tomography, X-Ray Computed
7.
Clin Anat ; 30(3): 342-346, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28165638

ABSTRACT

Epidural anesthesia is a versatile technique widely used in treating lumbar spinal pain syndromes. Complications during these procedures can arise either from needle placement or from administration of medication. Potential risks include infection, hematoma, intravascular or subdural injections of medication, direct nerve trauma, air embolism, entry into a disc space, urinary retention, radiation exposure, and hypersensitivity reactions. The objective of this article is to review the complications of lumbar epidural injections and discuss the potential pitfalls related to these procedures. We searched Medline comprehensively for relevant case reports, clinical trials, and review articles. Complications from lumbar epidural injections are extremely rare. Most if not all of them can be avoided by careful techniques with accurate needle placement, sterile precautions, and a thorough understanding of the relevant anatomy and contrast patterns on fluoroscopic imaging. Clin. Anat. 30:342-346, 2017. © 2017 Wiley Periodicals, Inc.


Subject(s)
Anesthesia, Epidural/adverse effects , Anesthetics, Local/adverse effects , Embolism, Air/etiology , Hematoma/etiology , Injections, Epidural/methods , Spinal Nerves/injuries , Anesthetics, Local/administration & dosage , Bupivacaine/administration & dosage , Embolism, Air/prevention & control , Hematoma/prevention & control , Humans , Injections, Epidural/adverse effects , Lidocaine/administration & dosage , Lidocaine/adverse effects , Low Back Pain/drug therapy
8.
J Clin Neurosci ; 38: 32-36, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28089196

ABSTRACT

INTRODUCTION: Spinal cord tumors (SCT) are relatively uncommon and usually require surgical treatment. Readmission within 30days after discharge is an important indicator of health care quality. The aim of this study was to investigate the rates and causes of unplanned readmissions and reoperations after SCT surgery. METHODS: A retrospective analysis of patients' charts at a single center from May 2007 to September 2015 was completed. INCLUSION CRITERIA: history of laminectomy with excision of neoplasm in the spinal cord. EXCLUSION CRITERIA: (1) surgery outside the timeframe; (2) less than 19years old; (3) non-neoplastic intramural pathologies; (4) previous resection at the same location; (5) metastatic lesions. RESULTS: We found 131 patients that met criteria. Six patients (4.5%) were readmitted within 30days and two within 90days (1.5%). Four underwent reoperation: one for a cerebrospinal fluid leak, two for pseudomenigoceles, and one for repeat laminectomy. Resection of intramedullary tumors resulted in twice the risk of having one or more complications compared to extramedullary tumors (RR 2.0; 95% CI: 1.0-4.2; p=0.057), and nearly four times the risk of having a neurological complication (RR 3.8; 95% CI 1.5-9.5; p=0.005). CONCLUSION: This study analyzes readmission, reoperation and complication rates for the surgical care of SCT highlighting how SCT surgery is still involved with morbidity in experienced and specialized centers. This information is useful both for health care enhancement projects and for evidence-based patient counseling.


Subject(s)
Neurosurgical Procedures/statistics & numerical data , Patient Readmission/statistics & numerical data , Postoperative Complications/surgery , Reoperation/statistics & numerical data , Spinal Cord Neoplasms/surgery , Adult , Aged , Aged, 80 and over , Female , Humans , Laminectomy/adverse effects , Laminectomy/statistics & numerical data , Male , Middle Aged , Neurosurgical Procedures/adverse effects , Postoperative Complications/etiology , Retrospective Studies , Young Adult
9.
World Neurosurg ; 98: 273-277, 2017 Feb.
Article in English | MEDLINE | ID: mdl-27836702

ABSTRACT

INTRODUCTION: The operating microscope (OM) has become instrumental in aiding surgeons during key microdissection with greater safety and detail. An exoscope offers similar detail with improved functionality and greater implications for live teaching and improved operating room flow. METHODS: Eleven senior neurosurgery residents and fellows performed unilateral, single-level laminotomies on fresh cadavers using an OM and exoscope. Three attending spine surgeons blinded for the visualization technique used then reviewed and graded each decompression. Data points gathered included time of procedure, grading of decompression (1-5), and complications, including dural tear, nerve root injury, and pars fracture. RESULTS: Operative times between the 2 systems were not significantly different (14.9 minutes OM vs. 15.6 minutes exoscope, P = 0.766). Despite high variability between evaluators in assessing complications and adequacy of decompression, there was no significant difference between either system. Postprocedural surveys indicated greater comfort with the exoscope, greater ease of use, and superior teaching potential for the exoscope over the standard OM. CONCLUSION: In our simulated operating room model, an exoscope is a valid alternative to the standard OM that affords the surgeon greater comfort with greater teaching potential while maintaining many of the microscope's benefits.


Subject(s)
Microscopy, Video/trends , Microsurgery/trends , Neurosurgical Procedures/trends , Robotic Surgical Procedures/trends , Spinal Cord/surgery , Cadaver , Humans , Laminectomy/methods , Laminectomy/trends , Microscopy, Video/methods , Microsurgery/methods , Neurosurgical Procedures/methods , Robotic Surgical Procedures/methods , Single-Blind Method , Spinal Cord/pathology
10.
Cureus ; 8(9): e785, 2016 Sep 16.
Article in English | MEDLINE | ID: mdl-27774355

ABSTRACT

A 69-year-old female with a history of breast cancer and hypertension presented with a rare case of herpes simplex encephalitis (HSE) isolated to her left parietal lobe. The patient's first biopsy was negative for herpes simplex virus (HSV) I/II antigens, but less than two weeks later, the patient tested positive on repeat biopsy. This initial failure to detect the virus and the similarities between HSE and symptoms of intracranial hemorrhage (ICH) suggests repeat testing for HSV in the presence of ICH. Due to the frequency of patients with extra temporal HSE, a diagnosis of HSE should be more readily considered, particularly when a patient may not be improving and a concrete diagnosis has not been solidified.

11.
Cureus ; 8(7): e668, 2016 Jul 05.
Article in English | MEDLINE | ID: mdl-27551648

ABSTRACT

Of patients who have undergone lateral approaches to the thoracic spine, surgical site postoperative pain appears to be greater among those who have undergone transection and removal of a rib segment than those who have not. Therefore, techniques that conserve anatomical position and minimize tissue disruption would theoretically result in less pain and a quicker recovery. Herein, we describe a rib-sparing osteoplastic technique used when rib segments need to be displaced in order to create an unobscured corridor to the operative target. Our approach minimizes soft tissue disruption and restores the anatomical function of the rib. Based on our experience, these patients report less pain, mobilize earlier, and are discharged sooner than those who have had rib segments sacrificed as part of a lateral approach to the spine.

12.
J Neurosurg Spine ; 25(6): 681-684, 2016 12.
Article in English | MEDLINE | ID: mdl-27448172

ABSTRACT

Venous air embolism (VAE) is a known neurosurgical complication classically and most frequently occurring in patients undergoing posterior cranial fossa or cervical spine surgery in a sitting or semi-sitting position. The authors present a case of VAE that occurred during posterior cervical spine surgery in a patient in the prone position, a rare intraoperative complication. The patient was a 65-year-old man who was undergoing a C1-2 fusion for a nonunion of a Type II dens fracture and developed a VAE. While VAE in the prone position is uncommon, it is a neurosurgical complication that may have significant clinical implications both intraoperatively and postoperatively. The aim of this review is 2-fold: 1) to improve the general knowledge of this complication among surgeons and anesthesiologists who may not otherwise suspect air embolism in patients positioned prone for posterior cervical spine operations, and 2) to formulate preventive measures as well as a plan for prompt diagnosis and treatment should this complication occur.


Subject(s)
Cervical Vertebrae/injuries , Cervical Vertebrae/surgery , Embolism, Air/etiology , Intraoperative Complications , Spinal Fractures/surgery , Spinal Fusion/adverse effects , Aged , Atlanto-Axial Joint/abnormalities , Atlanto-Axial Joint/blood supply , Congenital Abnormalities , Humans , Male , Prone Position , Reoperation , Spinal Fusion/methods
13.
Cureus ; 8(5): e623, 2016 May 27.
Article in English | MEDLINE | ID: mdl-27433402

ABSTRACT

Lumbar stenosis has become one of the most common spinal pathologies and one that results in neurogenic claudication, back and leg pain, and disability. The standard procedure is still an open laminectomy, which involves wide muscle retraction and extensive removal of the posterior spinal structures. This can lead to instability and the need for additional spinal fusion. We present a systemized and detailed approach to unilateral laminotomy for bilateral decompression, which we believe is superior to the standard open laminectomy in terms of intraoperative visualization, postoperative stability, and degree of invasiveness.

14.
Cureus ; 8(4): e560, 2016 Apr 06.
Article in English | MEDLINE | ID: mdl-27190725

ABSTRACT

Cavernous angiomas usually occur in the parenchyma of both the supra and infratentorial compartments. At times, they can both clinically and radiologically mimic other dural-based lesions. We present a case of a patient with chronic occipital headaches, initially thought to have a meningioma, but proven to be a cavernoma with histological analysis.

15.
Cureus ; 8(1): e469, 2016 Jan 27.
Article in English | MEDLINE | ID: mdl-26973804

ABSTRACT

The operative microscope has been a staple instrument in the neurosurgical operating room over the last 50 years. With advances in optoelectronics, options such as robotically controlled high magnification have become available. Such robotically controlled optoelectronic systems may offer new opportunities in surgical technique and teaching. However, traditionally trained surgeons may find it hard to accept newer technologies due to an inherent bias emerging from their previous background. We, therefore, studied how a medically naïve population in a pilot study would meet set microsurgical goals in a cadaver experiment using either a conventional operative microscope or BrightMatter™ Servo system, â€‹a robotically controlled optoelectronic system (Synaptive Medical, Toronto, Ontario, Canada). We found that the relative ease in teaching medical novices with a robotically controlled optoelectronic system was more valuable when compared to using a modern-day surgical microscope.

16.
Reg Anesth Pain Med ; 41(3): 402-4, 2016.
Article in English | MEDLINE | ID: mdl-26982079

ABSTRACT

OBJECTIVE: Spinal epidural steroid injections are generally considered a safe, effective treatment for radicular pain in a variety of spinal conditions. Complications secondary to these injections, although rare, can result in devastating neurologic symptoms. Patients with preexisting moderate-to-severe spinal stenosis and recent use of chronic anticoagulation pose a challenging dilemma when making treatment decisions, as a history of both can increase the risk of complications. CASE REPORT: The following case study provides a description of a patient with spinal stenosis who discontinued anticoagulation therapy according to the recommended guidelines but who experienced a subsequent acute epidural hematoma and significant neurologic injury. CONCLUSIONS: This case report describes the potential risk factors present in this patient. Presence of spinal stenosis and the interlaminar approach seem to be significant risk factors in this case. Presence of an intrinsic coagulopathy was not determined.


Subject(s)
Glucocorticoids/administration & dosage , Hematoma, Epidural, Spinal/etiology , Triamcinolone/administration & dosage , Acute Disease , Aged , Anticoagulants/administration & dosage , Anticoagulants/adverse effects , Decompression, Surgical , Drug Administration Schedule , Female , Hematoma, Epidural, Spinal/diagnosis , Hematoma, Epidural, Spinal/surgery , Humans , Injections, Epidural/adverse effects , Lumbar Vertebrae , Magnetic Resonance Imaging , Risk Factors , Spinal Stenosis/complications , Treatment Outcome
17.
Global Spine J ; 5(6): 523-6, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26682104

ABSTRACT

Study Design Case report. Objective Treatment of gunshot wounds to the spine is a topic of continued discussion and controversy. The following case study provides a description of a patient with a gunshot wound to the lumbar spine with a retained bullet in the intrathecal space. Methods Immediately after gunshot injury, a patient developed lumbar and radicular pain, as well as neurologic deficits. He was taken for surgery to remove the retained bullet. Results Following surgery, pain and neurologic function improved. The operative techniques and the postoperative clinical management are discussed in this report. Conclusion In our opinion, it was necessary to remove the bullet to avoid migration and possible worsening of neurologic function. However, surgical intervention is not appropriate in every case, and ultimately decisions should be based on patient presentation, symptomology, and imaging.

19.
Cureus ; 7(5): e268, 2015 May.
Article in English | MEDLINE | ID: mdl-26180692

ABSTRACT

Revision surgery to address the migration or fracture of a lumbar interbody cage can be technically challenging. Scar tissue and fibrosis, among other anatomic barriers, can make removal of the cage a complicated procedure, potentially increasing postoperative pain as well as the probability of neurologic deficits. Use of the lateral surgical technique for removal of the cage can avoid these potential complications. In this case report, we describe the removal of interbody cages through a lateral approach in three patients without the necessity of additional posterior hardware revision.

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