ABSTRACT
The records of 50 patients with primary carcinoma of the fallopian tube referred to postoperative radiotherapy at the Radium Centre of the Finsen Institute, Copenhagen, were reviewed. The most common symptoms were postmenopausal bleeding, vaginal watery discharge and abdominal pain. In 86% of the patients a palpable pelvic tumor was found at preoperative gynecologic examination. Disease was localized to the pelvis (stage I and stage II) in nearly all patients (92%). Ten patients were given radiotherapy as vaginal radium twice combined with deep X-ray to the pelvis, and 38 patients were given radiotherapy as high-voltage irradiation to the pelvis only. The overall survival at 5 years was 50.9%. Still, the role of radiotherapy in the control of this rare disease remains to be established. To obtain a better prognosis for this disease, international cooperative prospective studies are proposed.
Subject(s)
Adenocarcinoma/therapy , Fallopian Tube Neoplasms/therapy , Actuarial Analysis , Adenocarcinoma/mortality , Adenocarcinoma/pathology , Adenocarcinoma/secondary , Adult , Aged , Combined Modality Therapy , Fallopian Tube Neoplasms/mortality , Fallopian Tube Neoplasms/pathology , Female , Hormones/therapeutic use , Humans , Middle Aged , Neoplasm Recurrence, Local , Neoplasm Staging , Retrospective Studies , Uterine Hemorrhage/etiologySubject(s)
Microsurgery , Abortion, Spontaneous , Fallopian Tubes/surgery , Female , Follow-Up Studies , Humans , Pregnancy , Pregnancy, EctopicABSTRACT
The conception rate of 32 infertile women undergoing tubal microsurgery and subsequent artificial insemination by donor (AID) was compared with that of 71 women undergoing tubal microsurgery alone. The follow-up period ranged from 1 to 6 1/2 years. Nine (28%) of the patients in the AID group conceived, resulting in 8 (89%) live births and 1 (11%) spontaneous abortion. In the normal semen group 42 (59%) of the patients conceived, resulting in 31 (74%) live births, 6 (14%) tubal pregnancies and 5 (12%) spontaneous abortions. In the AID group the following term pregnancy rates were achieved: 40% after bilateral lysis of periadnexal adhesions, 25% after fimbriolysis and 14% after salpingostomy. The corresponding figures in the group with normal semen analysis was 67%, 64% and 29%, respectively. It is concluded that patients who in addition to tubal microsurgery have been treated with AID for 9-12 menstrual cycles seem to have about a 50% poorer chance of achieving a term pregnancy compared with patients whose husbands have normal semen quality.
Subject(s)
Fallopian Tubes/surgery , Insemination, Artificial, Heterologous , Insemination, Artificial , Adult , Female , Follow-Up Studies , Humans , Male , Pregnancy , Prognosis , Semen/analysisABSTRACT
The cumulative conception rate of 31 infertile women undergoing a second tuboplasty using microsurgery was compared with that 71 women undergoing a single microsurgical tuboplasty. The follow-up period ranged from ranged from 1 to 61/2 years. Five (16%) of the patients in the repeat tuboplasty group conceived; there were 3 (10%) live births, 1 (3%) tubal pregnancy, and 1 (3%) spontaneous abortion. In the single tuboplasty group 42 (59%) of the patients conceived, with the result of 31 (44%) liver births, 6 (9%) tubal pregnancies, and 5 (7%) spontaneous abortions. Reocclusion of both tubes occurred in 16% and 7% of the patients in the two groups, respectively. It is concluded that the poor results of repeated tuboplasties mainly are due to mucosal lesions, which in the majority of cases seem to be irreversible.
