ABSTRACT
A 40-year-old woman presented with red swelling of the right mandibular region of the face. She had several painful, progressive, ulcerative, raised serosanguinous discharging sinuses. The presence of granules and bony contents were not reported. She was an habitual tobacco and betel chewer for the past 20 years. There was no history of injury/trauma over the site in the past. Progressive loss of appetite and body weight was prominent. She was nonambulatory and denied treatment.
Subject(s)
Carcinoma, Squamous Cell/pathology , Mouth Neoplasms/pathology , Skin/pathology , Adult , Appetite , Areca/adverse effects , Carcinoma, Squamous Cell/diagnosis , Carcinoma, Squamous Cell/etiology , Female , Humans , Magnetic Resonance Imaging , Mandible , Mastication , Mouth Neoplasms/diagnosis , Mouth Neoplasms/etiology , Tobacco, Smokeless/adverse effects , Tomography, X-Ray Computed/methods , Weight LossABSTRACT
BACKGROUND: Vitiligo has a special significance in Indian patients both because depigmentation is obvious on darker skin and the enormous stigma associated with the disease in the culture. AIMS: This study was carried out to determine the beliefs about causation, aspects of the disease that cause concern, medical, and psychosocial needs of the patients, expectation from treatment and from the treating physician, and effects of disease on the patient's life. METHODS: Semi-structured interviews were conducted in 50 patients with vitiligo. Purposive sampling was used to select subjects for the study. Each interview was recorded on an audio-cassette and transcripts were analyzed to identify significant issues and concerns. RESULTS: Patients had a range of concerns regarding their disease such as physical appearance, progression of white patches onto exposed skin and the whole body, ostracism, social restriction, dietary restrictions, difficulty in getting jobs, and they considered it to be a significant barrier to getting married. The condition was perceived to be a serious illness. Stigma and suicidal ideation was reported. While there were several misconceptions about the cause of vitiligo, most patients did not think their disease was contagious, heritable or related to leprosy. Multiple medical consultations were frequent. Complete repigmentation was strongly desired, but a lesser degree of repigmentation was acceptable if progression of disease could be arrested. The problems were perceived to be more severe in women. The disease imposed a significant financial burden. CONCLUSION: Addressing psychosocial factors is an important aspect of the management of vitiligo, particularly in patients from communities where the disease is greatly stigmatizing.
Subject(s)
Stress, Psychological/psychology , Vitiligo/psychology , Adolescent , Adult , Aged , Child , Child, Preschool , Employment/psychology , Female , Humans , India , Interviews as Topic , Male , Marriage/psychology , Middle Aged , Psychology , Skin Pigmentation , Young AdultABSTRACT
BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the most severe adverse drug reactions in children. OBJECTIVES: The objective was to study the causative drugs and outcome in children with SJS, SJS-TEN overlap, and TEN. MATERIALS AND METHODS: Retrospective analysis of all the in-patient records of children below 18 years of age with the diagnosis of SJS, SJS-TEN overlap, and TEN was carried out. RESULTS AND CONCLUSIONS: Twenty children were identified, eight patients each were diagnosed as SJS and TEN and four as SJS-TEN overlap. Multiple drugs were implicated in 15 cases while single drug was responsible in 5 cases. Antibiotics (40.7%) were implicated as the commonest cause followed by NSAIDS (25.9%) and anticonvulsants (7.4%). Seventeen patients recovered completely and three patients died.
ABSTRACT
We report a 60-year-old man who presented with a 2-year history of painless red raised lesions involving the tongue and scrotum. Histopathology was suggestive of angiokeratoma. Oral angiokeratomas are most commonly found as a component of the generalized systemic disorder in Fabry's disease or fucosidosis. Our patient had isolated mucosal angiokeratomas which is very rare.
Subject(s)
Cholinergic Neurons/physiology , Seasons , Urticaria/etiology , Urticaria/pathology , Adolescent , Adult , Female , Humans , Male , Temperature , Young AdultABSTRACT
Becker's nevus otherwise known as Becker's pigmented hairy nevus, is a common melanotic epidermal hypermelanosis. It usually presents as a large unilateral patch of hyperpigmentation and hypertrichosis on the shoulder, chest, or back of an adult man. It can be bilateral or multiple and affect areas other than the usual sites. We report a 16-year-old boy with two Becker's nevi on the left side of the face in a segmental distribution with extension onto the oral mucosa. This case is being reported for its rare presentation.
Subject(s)
Mouth Neoplasms/pathology , Nevus/pathology , Skin Neoplasms/pathology , Adolescent , Face , Humans , Male , Mucous Membrane/pathologyABSTRACT
Syringocystadenoma papilliferum is a rare benign adnexal skin tumor of apocrine or eccrine glands. We report here an 18-year-old girl who had linear syringocystadenoma papilliferum in the pubic region, which is very rare.
Subject(s)
Cystadenoma/diagnosis , Sweat Gland Neoplasms/diagnosis , Syringoma/diagnosis , Adolescent , Cystadenoma/pathology , Cystadenoma/surgery , Female , Humans , Quality of Life , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/surgery , Syringoma/pathology , Syringoma/surgery , Treatment OutcomeABSTRACT
Glomus tumours of the nail bed are an excruciatingly painful condition. The treatment of choice for these is surgical excision. However, since most cases are treated by surgeons, the usual method of treatment is total nail avulsion and excision. We have treated two patients of this rare presentation with a nail plate-conserving surgical method called the 'trap door' technique with excellent results. We hereby present a step-by-step pictorial guide to the method.
