ABSTRACT
STUDY OBJECTIVE: The objective of this study is to show that patients with corneal abrasions would experience more pain relief with short-term topical tetracaine than placebo. METHODS: The study was a prospective, double-blind, randomized trial of tetracaine versus placebo set in the emergency department (ED). A total of 118 adults who presented with uncomplicated corneal abrasions were included and randomized. The intervention was either topical tetracaine or placebo applied every 30 minutes as needed for 24 hours. The primary outcome was the overall numeric rating scale pain score measured at the 24- to 48-hour ED follow-up examination. RESULTS: One hundred eleven patients were included in the final analysis, 56 in the tetracaine group and 55 in the placebo group. At the 24- to 48-hour follow-up, the overall numeric rating scale pain score after use of the study drops was significantly lower in the tetracaine group (1) versus placebo group (8) (Δ7; 95% confidence interval 6 to 8). Patients in the tetracaine group used less hydrocodone than those in the placebo group. The complication rates between the 2 groups were similar. CONCLUSION: Short-term topical tetracaine is an efficacious analgesic for acute corneal abrasions, is associated with less hydrocodone use compared with placebo, and was found to be safe in this sample.
Subject(s)
Analgesics/administration & dosage , Corneal Injuries/complications , Eye Pain/drug therapy , Tetracaine/administration & dosage , Administration, Topical , Adolescent , Adult , Aged , Aged, 80 and over , Analgesics/therapeutic use , Double-Blind Method , Drug Administration Schedule , Eye Pain/etiology , Female , Follow-Up Studies , Humans , Male , Middle Aged , Pain Measurement , Prospective Studies , Tetracaine/therapeutic use , Treatment Outcome , Young AdultABSTRACT
Lightning strikes to people are rare events that cause significant injuries and mortality when they do occur. We describe an uncommon case of a storm chaser in Oklahoma who was struck by lightning who suffered cutaneous burns, bilateral tympanic membrane ruptures, as well as pulmonary edema, which is an atypical finding in survivors. This case report highlights several injury patterns seen in lightning strike cases and provides evidence that these patients should be managed at a center with multidisciplinary services available.
Subject(s)
Burns, Electric/etiology , Lightning Injuries/complications , Lightning , Pulmonary Edema/etiology , Adult , Humans , Male , Oklahoma , SurvivorsABSTRACT
Timely diagnosis of acute coronary occlusion is essential to avoid chronic cardiac impairment and death. We describe an uncommon case of acute myocardial infarction masked by low QRS voltage secondary to morbid obesity. This case highlights the importance of considering the degree of ST-segment elevation proportionally to the QRS amplitude if there is clinical suspicion of acute coronary occlusion.
