Light Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing.

RATIONALE: For decades, cannabis has been the most widely used illicit substance in the world, particularly among youth. Research suggests that mental health problems associated with cannabis use may result from its effect on reward brain circuit, emotional processes, and cognition. However, findings are mostly derived from correlational studies and inconsistent, particularly in adolescents. OBJECTIVES AND METHODS: Using data from the IMAGEN study, participants (non-users, persistent users, abstinent users) were classified according to their cannabis use at 19 and 22 years-old. All participants were cannabis-naïve at baseline (14 years-old). Psychopathological symptoms, cognitive performance, and brain activity while performing a Monetary Incentive Delay task were used as predictors of substance use and to analyze group differences over time. RESULTS: Higher scores on conduct problems and lower on peer problems at 14 years-old (n = 318) predicted a greater likelihood of transitioning to cannabis use within 5 years. At 19 years of age, individuals who consistently engaged in low-frequency (i.e., light) cannabis use (n = 57) exhibited greater conduct problems and hyperactivity/inattention symptoms compared to non-users (n = 52) but did not differ in emotional symptoms, cognitive functioning, or brain activity during the MID task. At 22 years, those who used cannabis at both 19 and 22 years-old n = 17), but not individuals that had been abstinent for ≥ 1 month (n = 19), reported higher conduct problems than non-users (n = 17). CONCLUSIONS: Impairments in reward-related brain activity and cognitive functioning do not appear to precede or succeed cannabis use (i.e., weekly, or monthly use). Cannabis-naïve adolescents with conduct problems and more socially engaged with their peers may be at a greater risk for lighter yet persistent cannabis use in the future.

Modeling relations between event-related potential factors and broader versus narrower dimensions of externalizing psychopathology.

The organization of the Hierarchical Taxonomy of Psychopathology (HiTOP) model provides unique opportunities to evaluate whether neural risk measures operate as indicators of broader latent liabilities (e.g., externalizing proneness) or narrower expressions (e.g., antisociality and alcohol abuse). Following this approach, the current study recruited a sample of 182 participants (54% female) who completed measures of externalizing psychopathology (also internalizing) and associated traits. Participants also completed three tasks (Flanker-No Threat, Flanker-Threat, and Go/No-Go tasks) with event-related potential (ERP) measurement. Three variants of two research domain criteria (RDoC)-based neurophysiological indicators-P3 and error-related negativity (ERN)-were extracted from these tasks and used to model two latent ERP factors. Scores on these two ERP factors independently predicted externalizing factor scores when accounting for their covariance with sex-suggesting distinct neural processes contributing to the broad externalizing factor. No predictive relation with the broad internalizing factor was found for either ERP factor. Analyses at the finer-grained level revealed no unique predictive relations of either ERP factor with any specific externalizing symptom variable when accounting for the broad externalizing factor, indicating that ERN and P3 index general liability for problems in this spectrum. Overall, this study provides new insights about neural processes in externalizing psychopathology at broader and narrower levels of the HiTOP hierarchy. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Uncertainty deconstructed: conceptual analysis and state-of-the-art review of the ERP correlates of risk and ambiguity in decision-making.

Risk and uncertainty are central concepts of decision neuroscience. However, a comprehensive review of the literature shows that most studies define risk and uncertainty in an unclear fashion or use both terms interchangeably, which hinders the integration of the existing findings. We suggest uncertainty as an umbrella term that comprises scenarios characterized by outcome variance where relevant information about the type and likelihood of outcomes may be somewhat unavailable (ambiguity) and scenarios where the likelihood of outcomes is known (risk).These conceptual issues are problematic for studies on the temporal neurodynamics of decision-making under risk and ambiguity, because they lead to heterogeneity in task design and the interpretation of the results. To assess this problem, we conducted a state-of-the-art review of ERP studies on risk and ambiguity in decision-making. By employing the above definitions to 16 reviewed studies, our results suggest that: (a) research has focused more on risk than ambiguity processing; (b) studies assessing decision-making under risk often implemented descriptive-based paradigms, whereas studies assessing ambiguity processing equally implemented descriptive- and experience-based tasks; (c) descriptive-based studies link risk processing to increased frontal negativities (e.g., N2, N400) and both risk and ambiguity to reduced parietal positivities (e.g., P2, P3); (d) experience-based studies link risk to increased P3 amplitudes and ambiguity to increased frontal negativities and the LPC component; (e) both risk and ambiguity processing seem to be related with cognitive control, conflict monitoring, and increased cognitive demand; (f) further research and improved tasks are needed to dissociate risk and ambiguity processing.

Subjective Memory Complaints and Decision Making in Young and Older Adults: An Event-Related Potential Study.

Subjective memory complaints (SMCs) may affect decision-making processes. This study aimed to investigate the neuronal correlates of feedback processing during a decision-making task in young and older adults with and without SMCs. Event-related potentials and behavioral performance during the Iowa gambling task were recorded in a total of 136 participants (65 young adults, 71 older adults). The participants were divided into two groups according to their SMCs (with SMCs: n = 60, without SMCs: n = 76). Feedback-related negativity (FRN) and P3 were analyzed in the feedback stage of the decision-making process. Older adults with SMCs scored worse in the ambiguity phase than older adults without SMCs. The FRN latency was longer for losses in older people with SMCs than in older people without SMCs in the first block. No significant differences between young and older adults with and without SMCs were observed in the other ERP measures. Compared to young adults, older adults showed delayed latency in the FRN component and reduced amplitudes and delayed latency in the P3 component. In conclusion, older people with SMCs present deficits in the decision-making process. These deficits are observed at the behavioral level, but also in neural mechanisms of early feedback processing of negative outcomes.

An ERP study on facial emotion processing in young people with subjective memory complaints.

Subjective memory complaints (SMCs) are commonly related to aging, but they are also presented by young adults. Their neurophysiological mechanisms are not thoroughly understood, although some aspects related to affective state have been mentioned. Here, we investigated whether facial emotion processing is different in young people with (n = 41) and without (n = 39) SMCs who were exposed to positive, negative, and neutral faces, by recording the event-related potential (ERP) activity. From the ERP activity, the N170 (an index of face processing) and the LPP (an index of motivated attention) components were extracted. Regarding the N170, results showed less amplitude for positive and neutral faces in the participants with SMCs than in those without SMCs. Moreover, women with SMCs displayed longer latencies for neutral faces than women without SMCs. No significant differences were found between the groups in the LPP component. Together, our findings suggest deficits in an early stage of facial emotion processing in young people with SMCs, and they emphasize the importance of further examining affective dimensions.

Boldness Personality Traits Are Associated With Reduced Risk Perceptions and Adoption of Protective Behaviors During the First COVID-19 Outbreak.

The containment measures imposed during the first COVID-19 outbreak required economic, social, and behavioral changes to minimize the spread of the coronavirus. Some studies have focused on how personality predicts distinct patterns of adherence to protective measures with psychopathic and antisocial traits predicting reduced engagement in such measures. In this study we extended previous findings by analyzing how boldness, meanness, and disinhibition psychopathic traits relate with both risk perceptions and protective behaviors during the first COVID-19 outbreak. A sample of 194 individuals (24% male) engaged in the survey, were assessed for psychopathic traits with the Triarchic Psychopathy Measure, and completed a COVID-19 survey targeting risk perceptions (spread, risk of becoming infected, state anxiety toward the COVID-19, and perceived risk of specific behaviors) and frequency of protective behaviors (e.g., not engaging in social distancing). Overall results show that boldness predicts reduced estimate of COVID-19 spread, reduced perceived risk of becoming infected, reduced state anxiety toward COVID-19, and reduced frequency of protective behaviors. Exploratory mediation models suggest that risk perceptions are not significant mediators of the association between psychopathic traits and reduced engagement in protective behaviors. Our results unveil that psychopathic traits affect risk perceptions and the propensity to engage in protective measures, emphasizing the need to accommodate these personality features in the public health strategy to control the COVID-19 spread.

Abnormal Habituation of the Auditory Event-Related Potential P2 Component in Patients With Schizophrenia.

Auditory event-related potentials (ERP) may serve as diagnostic tools for schizophrenia and inform on the susceptibility for this condition. Particularly, the examination of N1 and P2 components of the auditory ERP may shed light on the impairments of information processing streams in schizophrenia. However, the habituation properties (i.e., decreasing amplitude with the repeated presentation of an auditory stimulus) of these components remain poorly studied compared to other auditory ERPs. Therefore, the current study used a roving paradigm to assess the modulation and habituation of N1 and P2 to simple (pure tones) and complex sounds (human voices and bird songs) in 26 first-episode patients with schizophrenia and 27 healthy participants. To explore the habituation properties of these ERPs, we measured the decrease in amplitude over a train of seven repetitions of the same stimulus (either bird songs or human voices). We observed that, for human voices, N1 and P2 amplitudes decreased linearly from stimulus 1-7, in both groups. Regarding bird songs, only the P2 component showed a decreased amplitude with stimulus presentation, exclusively in the control group. This suggests that patients did not show a fading of neural responses to repeated bird songs, reflecting abnormal habituation to this stimulus. This could reflect the inability to inhibit irrelevant or redundant information at later stages of auditory processing. In turn schizophrenia patients appear to have a preserved auditory processing of human voices.

O Brasil conta comigo na pandemia da Covid-19: ensaio reflexivo sobre a antecipação da formação em Enfermagem / Brazil counts on me in the Covid-19 pandemic: a reflective essay on advancing the timeline of Nursing education

Diante da atual pandemia de Covid-19, foi criada a Ação Estratégica "O Brasil Conta Comigo - Profissionais da Saúde", direcionada à capacitação e ao cadastramento de trabalhadores da saúde. Alinhada a essa estratégia, foi lançada uma portaria do Ministério da Educação que autoriza a antecipação da colação de grau para profissões da saúde, o que desencadeou uma onda de formaturas antecipadas. O contexto em questão instigou-nos a elaborar um ensaio reflexivo acerca dos problemas que envolvem a antecipação da formação de enfermeiros. As reflexões foram tecidas com base em referenciais teóricos que desvelam o cinismo no discurso governamental em voga. Concluímos que em vez de uma medida resolutiva para amenizar déficit de mão de obra, as iniciativas governamentais representam um retrocesso nos campos da educação e da saúde que inviabiliza a reversão da histórica precariedade nas condições de trabalho na Enfermagem. (AU)

The Strategic Action "Brasil Conta Comigo - Profissionais da Saúde" was created in the context of the current Covid-19 pandemic, directed to train and keep records of health workers. Aligned with this strategy, the Ministry of Education has issued an Ordinance authorizing to advance the timeline of graduation for health professions, triggering a wave of early graduations. This context prompted us to prepare a reflective essay on the problems involved when nurses' education is cut short. The reflections were woven based on theoretical references that unveil the cynicism present in the current government discourse. We conclude that, instead of a problem-solving measure to alleviate the labor deficit, government initiatives represent a setback in the field of education and health that precludes the reversion of the historical precariousness in nursing working conditions. (AU)

Ante la pandemia actual de Covid-19, se creó la Acción Estratégica "Brasil cuenta conmigo - Profesionales de la salud", dirigida a la capacitación y el registro de trabajadores de la salud. Alineada a esa estrategia, se lanzó el Decreto Administrativo del Ministerio de Educación que autoriza la anticipación de la entrega de diploma a profesiones de la salud, lo que desencadenó una ola de graduaciones anticipadas. El contexto en cuestión nos instigó a elaborar un ensayo reflexivo sobre los problemas que envuelven la anticipación de la formación de enfermeros. Tales reflexiones se tejieron con base en referenciales teóricos que desvelan el cinismo en el discurso gubernamental en boga. Concluimos que, en lugar de una medida de resolución para atenuar el déficit de mano de obra, las iniciativas gubernamentales representan un retroceso en el campo de la educación y de la salud que inviabiliza la reversión de la histórica precariedad en las condiciones de trabajo de Enfermería. (AU)

A saúde mental do enfermeiro frente à pandemia COVID-19 / The mental health of nurses handling the Covid-19 Pandemic: an integrative revision

Objetivo: identificar na literatura nacional e internacional a repercussão na saúde mental do enfermeiro que atua na linha de frente do cuidado na pandemia do novo coronavírus (COVID- 19), desde o início dos casos registrados em Wuhan. Metodologia: revisao integrativa da literatura realizada no mes de abril de 2020, mediante consulta as bases de dados Biblioteca Virtual em Sa.de (BVS); e do Medical Subject Headings (MeSH) da National Library., Scopus e CINAHL. Resultado: nove artigos foram incluídos na amostra, eles destacam a escacess de recursos materiais nos hospitais e a prevalencia de níveis mais altos de sofrimento mental entre os enfermeiros em hospitais quando comparados a outras categorias profissionais na linha de frente do cuidado. Conclusão: fica evidenciado que a saúde mental dos enfermeiros lidando com a pandemia de Covid-19 é um tema que denamda mais atenção não só dos pesquiadores, mas também dos gestores em saúde e outras autoridades responsáveis por políticas de saúde. (AU)

Objective: identifying in Brazilian and international scientific literature, the mental health repercussions caused by the new coronavirus ( COVID 19) in nurses working on the front line of healthcare systems since the pandemic outbreak in Wuhan. Methodology: an integrative literature revision was made in April 2020 into the following databases: Virtual Health Library, Brazil (BVS); Medical Subject Headings (MeSH), USA; Scopus, and CINALH. Results: nine papers were included in the final sample; they highlighted the scarcity of material resources in the hospitals and the prevalence of higher levels of mental health suffering in the nurses compared to the other professional workers on the frontline. Conclusion: it is evident that the mental health of nurses handling the Covid-19 pandemic is a topic that needs more attention not only from researchers but also from health managers and other authorities in charge of health policies. (AU)

Objetivo: identificar en la literatura científica brasileña e internacional, las repercusiones en la salud mental causadas por el nuevo coronavirus (COVID 19) en enfermeras que trabajan en la primera línea de los sistemas de salud desde el brote de la pandemia en Wuhan. Metodología: en abril de 2020 se realizó una revisión integral de la literatura en las siguientes bases de datos: Biblioteca Virtual en Salud, Brasil (BVS); Encabezamientos de temas médicos (MeSH), EE. UU.; Scopus y CINALH. Resultados: se incluyeron nueve artículos en la muestra final; destacaron la escasez de recursos materiales en los hospitales y la prevalencia de mayores niveles de sufrimiento de salud mental en las enfermeras en comparación con los otros trabajadores profesionales en primera línea. Conclusión: es evidente que la salud mental de las enfermeras que manejan la pandemia de Covid-19 es un tema que necesita más atención no solo de los investigadores sino también de los gerentes de salud y otras autoridades a cargo de las políticas de salud. (AU)

The AGE Effect on Protective Behaviors During the COVID-19 Outbreak: Sociodemographic, Perceptions and Psychological Accounts.

COVID-19 outbreak is a sudden and devastating global pandemic in which the control of the spread is highly dependent on individual reactions, until the development of a vaccine and adequate treatments. Considering that older adults are at high risk for COVID-related medical complications and mortality, the present study focuses on the age-related differences on the adoption of protective behaviors during the initial stages of this outbreak, while accounting for the role of sociodemographic, COVID-related, perceived risk, and psychosocial variables (i.e., anxiety, optimism, fear of death, and social isolation) in this relation. The study sample included 1696 participants, aged between 18 and 85 years old, who completed an online survey during the initial stages of the first COVID-19 outbreak in Portugal. Overall, results reveal that the engagement in protective behaviors declines with advancing age and that older adults show a pattern toward lower perceived risk compared with middle-aged adults. Multicategorical mediation analyses show that anxiety, optimism, fear of death, and social isolation significantly mediate age effects on protective behaviors. Specifically, both anxiety and fear of death increase protective behaviors via higher perceived risk in the middle-aged and in the younger groups, respectively. Optimism directly predicts protective behaviors in the middle-aged groups, while social isolation reduces protective behaviors in the younger and older-aged groups. Results are discussed in terms of its implications for public health policies.

Neurophysiological Correlates of the Near-Miss Effect in Gambling.

The near-miss effect in gambling refers to a losing situation that is (or perceived to be) close to a win by the gambler. This effect is one of the many cognitive distortions that can occur during gambling games. The main objective of the present study was to analyze the electrophysiological correlates of the near-miss effect via an event-related potential (ERP) study examining four distinct gambling outcomes: win, full miss, near-miss before the payline, and near-miss after the payline. This study comprised 23 healthy voluntary participants (10 women) with ages ranging between 19 and 34 years (M = 22.5; SD = 3.65). All participants completed the South Oaks Gambling Screen and played a computerized slot machine, programed to induce the near-miss effect and specifically designed for an ERP study. By splitting the near-miss effect in two subtypes (before and after the payline), increased feedback-related negativity (FRN) was found for the near-misses after the payline in comparison to losses and also to near-misses before the payline. Results also indicated an increased P300 amplitude for the near-misses before the payline compared both with losses and with near-misses after the payline. The results suggest that both FRN and P300 present different sensitivities to near-miss subtypes, suggesting a payline effect that is not demonstrated when the data of near-misses before and after the payline are analyzed together. This is the first study to analyze the effect of the near-miss subtype in an ERP study and confirms the findings of previous behavioral studies.

The neurophysiological correlates of the triarchic model of psychopathy: An approach to the basic mechanisms of threat conditioning and inhibitory control.

The psychopathic traits boldness, meanness, and disinhibition are theorized to be underlined by trait fearlessness and externalizing vulnerability as etiologic neurobiological processes. However, little is known about the neurophysiological correlates of these traits. In this work, we explored how the three traits are associated with event-related potential (ERP) components targeted at the etiological processes in a partial delayed threat conditioning task and in a go/no-go task. Fifty community-dwelling volunteers (25 women), without history of neurological or psychiatric conditions, were recruited and assessed for psychopathic traits using the triarchic psychopathy measure. Participants performed a threat conditioning task, and a go/no-go task while undergoing an electroencephalography recording. Results from the threat conditioning task showed that boldness was significantly associated with reduced late positive potential. Concerning the go/no-go task, disinhibition was significantly associated with reduced error-related negativity ERP component. Overall, distinct psychopathic traits were found to be associated with distinct neurophysiological correlates of threat conditioning and response inhibition. This is consistent with models of psychopathy entailing trait fearlessness and externalizing proneness, and related brain mechanisms, as distinct processes underlying the expression of psychopathic traits.

Further evaluation of the Triarchic Psychopathy Measure: Evidence from community adult and prisoner samples from Portugal.

The Triarchic Measure of Psychopathy (TriPM) was developed to assess manifest expressions of biobehavioural liabilities relevant to psychopathy and other forms of mental illness. Psychometric findings have been examined for a number of international translations of the TriPM, but further work is needed to evaluate its cross-cultural applicability and its properties in clinical versus nonclinical samples. The present study sought to evaluate the reliability and criterion-related validity and characterize the internal factor structure of the European Portuguese version of the TriPM in a large community sample (N = 1,833), and examine its ability to differentiate between community and prisoner (N = 240) samples. Reliability and criterion-related validity analysis supported the TriPM as an effective measure of psychopathic traits. Internal structure was characterized using exploratory structural equation modeling to specify bifactor models for the TriPM's three subscales and for the inventory as a whole; the model for each subscale included a general factor and a variable number of specific factors as determined by parallel analysis. These modeling analyses demonstrated unidimensionality for each TriPM subscale, and provided support for the triarchic structure of the TriPM as a whole. Additionally, Receiver Operating Characteristics analysis showed that the disinhibition score, as assessed by the TriPM, is the most sensitive for differentiating between prisoner and community samples. Our results are in line with other reports regarding the psychometric properties of the TriPM and provide further evidence for the construct validity of the TriPM. (PsycINFO Database Record (c) 2020 APA, all rights reserved).

The multiple facets of psychopathy in attack and defense conflicts.

With respect to De Dreu and Gross's article, we comment on the psychological functions for attack and defense, focusing on associations between individual differences in psychopathic personality traits and the behavioral patterns observed in attack-defense conflicts. We highlight the dimensional nature of psychopathy and formulate hypothetical associations between distinct traits, their different behavioral outcomes, and associated brain mechanisms.

Effect of Computer-Simulated Leaders' Compromise on Members' Emotional State and Protest Behavior.

Participants (N = 119) played the "Dictator Game" (computer mediated) with two bogus computer-simulated players, one of whom, the Dictator, distributed money across ten trials, either as extremely unfair (Inflexible Dictator) or being less unfair (Flexible Dictator). The other player either protested against (Protest condition) or did not react (Apathy condition) to the dictator's decision, after each trial. We measured participants' self-reported anger and disinterest, physiological skin conductance (SCL), heart rate (HR), and number and type of comments directed to the Dictator. Anger and number of comments were lower in the Apathy than in the Protest condition. Participants' SCL, HR, and protest comments decreased in the Apathy condition, and increased in the Protest condition. Protest assumed a more punitive tone in the Inflexible than in the Flexible Dictator condition. We discuss these results' contribution to understand individuals' motivation to engage in protest and apathy, and the role of emotions in that process.

Effects of 3D Contemplative Landscape Videos on Brain Activity in a Passive Exposure EEG Experiment.

Background: Studies on Contemplative Landscapes (CL) show that not only do they have high ecological and visual values and are preferred by a majority of people, but they also can be beneficial to our mental health and well-being. Physical attributes of CL have been studied and operationalized, which has led to the development of the psychometric measurement tool called the Contemplative Landscape Questionnaire (CLQ) (1). Objectives: In the present study, we applied an experimental approach to the analysis of CL. We hypothesized that, when compared to Non-Contemplative Landscapes (NCL), they would induce higher frontal alpha power asymmetry, higher temporal beta power asymmetry and lower bilateral frontal beta power. Methods: Thirty-two healthy individuals (12 female) took part in the study. During the experimental protocol, participants were asked to passively view 12 landscapes, six CL and six NCL, while continuous EEG was recorded in a within-subjects design. Results: We found significantly increased power in the beta frequency band of the right temporal brain regions in the viewings of CL compared to NCL Conclusions: The findings suggest that Contemplative Landscapes capture more visual, stimuli-driven attention from the viewers and can be linked with switching attention systems (described in Attention Restoration Theory), which is compatible with a stress reduction mechanism.

European Portuguese adaptation and validation of dilemmas used to assess moral decision-making.

Objective To adapt and validate a widely used set of moral dilemmas to European Portuguese, which can be applied to assess decision-making. Moreover, the classical formulation of the dilemmas was compared with a more focused moral probe. Finally, a shorter version of the moral scenarios was tested. Methods The Portuguese version of the set of moral dilemmas was tested in 53 individuals from several regions of Portugal. In a second study, an alternative way of questioning on moral dilemmas was tested in 41 participants. Finally, the shorter version of the moral dilemmas was tested in 137 individuals. Results Results evidenced no significant differences between English and Portuguese versions. Also, asking whether actions are "morally acceptable" elicited less utilitarian responses than the original question, although without reaching statistical significance. Finally, all tested versions of moral dilemmas exhibited the same pattern of responses, suggesting that the fundamental elements to the moral decision-making were preserved. Conclusions We found evidence of cross-cultural validity for moral dilemmas. However, the moral focus might affect utilitarian/deontological judgments.

European Portuguese adaptation and validation of dilemmas used to assess moral decision-making / Adaptação e validação para português europeu de dilemas utilizados para avaliar a tomada de decisão moral

Abstract Objective To adapt and validate a widely used set of moral dilemmas to European Portuguese, which can be applied to assess decision-making. Moreover, the classical formulation of the dilemmas was compared with a more focused moral probe. Finally, a shorter version of the moral scenarios was tested. Methods The Portuguese version of the set of moral dilemmas was tested in 53 individuals from several regions of Portugal. In a second study, an alternative way of questioning on moral dilemmas was tested in 41 participants. Finally, the shorter version of the moral dilemmas was tested in 137 individuals. Results Results evidenced no significant differences between English and Portuguese versions. Also, asking whether actions are "morally acceptable" elicited less utilitarian responses than the original question, although without reaching statistical significance. Finally, all tested versions of moral dilemmas exhibited the same pattern of responses, suggesting that the fundamental elements to the moral decision-making were preserved. Conclusions We found evidence of cross-cultural validity for moral dilemmas. However, the moral focus might affect utilitarian/deontological judgments.

Resumo Objetivos Validar e adaptar para português europeu um conjunto de dilemas morais amplamente utilizado, que poderá ser aplicado para avaliar a tomada de decisão moral. Além disso, comparou-se a formulação clássica dos dilemas com uma versão alternativa, que incluía uma questão mais focada na moralidade. Finalmente, testou-se uma versão reduzida dos cenários morais. Métodos A versão portuguesa dos dilemas morais foi testada em 53 participantes de várias regiões de Portugal, e a versão alternativa foi testada em 41 sujeitos. Finalmente, a versão reduzida dos dilemas morais foi testada numa amostra de 137 participantes. Resultados Não houve diferenças significativas entre a versão portuguesa e a inglesa. A pergunta "É moralmente aceitável...?" evocou menos respostas utilitárias que a versão original, embora não tenham sido obtidas diferenças significativas. A versão portuguesa original, a alternativa e a reduzida evidenciaram o mesmo padrão de respostas, sugerindo que os elementos fundamentais para a tomada de decisão moral estão preservados. Conclusões Encontramos evidências para a validade intercultural dos dilemas morais. No entanto, o foco moral colocado na questão final pode afetar os juízos utilitários/deontológicos.

Impact of a three-month resistance training program for elderly persons with knee osteoarthritis residing in the community of Santa Cruz, Rio Grande do Norte, Brazil / Impacto de um programa de três meses de exercícios resistidos para idosos com osteoartrite de joelhos, da comunidade de Santa Cruz, Rio Grande do Norte, Brasil

Abstract Objective: to evaluate the impact of a three-month resistance exercise program on the pain and functionality of elderly patients with knee osteoarthritis from the city of Santa Cruz, Rio Grande do Norte. Method: a quasi-experimental study was performed with 13 elderly patients diagnosed with knee osteoarthritis, who underwent a resistance training program twice a week for 12 weeks. Pain, muscle strength, functionality, quality of life and patient satisfaction were evaluated using the following instruments: the visual analog scale, one repetition maximum testing, the Western Ontario and McMaster Universities Osteoarthritis Index, the Timed Up and Go Test, the 6-minute walk Test, the Short Form (36) Health Survey and the Likert scale. The paired T-test and ANOVA for repeated measures were used for statistical analysis. Results: the mean age of the patients was 62.0 (±10.0) years. At the end of the study, the pain, muscle strength, functional status and some areas of quality of life of the elderly had improved. Conclusion: resistance exercises were an effective and safe method of improving the pain, muscle strength, functionality and quality of life of the population studied. The elderly should be encouraged to perform supervised strength training therapy. AU

Resumo Objetivo: avaliar o impacto de um programa de três meses de exercícios resistidos na dor e funcionalidade de idosos com osteoartrite de joelhos, da cidade de Santa Cruz, RN. Método: estudo quase experimental, com 13 idosos com diagnóstico médico de osteoartrite de joelhos, que realizaram um programa de exercícios resistidos duas vezes por semana, durante 12 semanas. A dor, força muscular, funcionalidade, qualidade de vida e satisfação do paciente foram avaliadas através dos instrumentos: Escala visual analógica de dor, Teste de uma repetição máxima (1RM), questionário The Western Ontario and McMaster Universities Osteoarthritis Index, Teste Timed Up and Go, Teste de caminhada de seis minutos, questionário Short Form (36) Health Survey e escala Likert. Teste t pareado e ANOVA de medidas repetidas foram utilizados para análise estatística. Resultados: a média de idade dos pacientes foi de 62,0 (±10,0) anos. Ao final do estudo, os idosos melhoraram a dor, aumentaram a força muscular, ficaram mais funcionais e melhoraram alguns domínios da qualidade de vida. Conclusão: os exercícios resistidos foram efetivos e seguros na melhora da dor, força muscular, funcionalidade e qualidade de vida, no grupo estudado. Idosos da comunidade devem ser encorajados a realizar musculação terapêutica supervisionada. AU

Assessing a novel polymer-wick based electrode for EEG neurophysiological research.

BACKGROUND: The EEG technique has decades of valid applications in clinical and experimental neurophysiology. EEG equipment and data analysis methods have been characterized by remarkable developments, but the skin-to-electrode signal transfer remains a challenge for EEG recording. NEW METHOD: A novel quasi-dry system - the polymer wick-based electrode - was developed to overcome the limitations of conventional dry and wet silver/silver-chloride (Ag/AgCl) electrodes for EEG recording. RESULTS: Nine participants completed an auditory oddball protocol with simultaneous EEG acquisition using both the conventional Ag/AgCl and the wick electrodes. Wick system successfully recorded the expected P300 modulation. COMPARISON WITH EXISTING METHOD(S): Standard ERP analysis, residual random noise analysis, and single-trial analysis of the P300 wave were performed in order to compare signal acquired by both electrodes. It was found that the novel wick electrode performed similarly to the conventional Ag/AgCl electrodes. CONCLUSIONS: The developed wick electrode appears to be a reliable alternative for EEG research, representing a promising halfway alternative between wet and dry electrodes.