ABSTRACT
Thirty-year experience in surgical treatment of more than 3,000 patients with severe and moderately severe bronchial asthma showed that unilateral glomectomy produces a stable positive result in 69.5% of patients in follow-up repiods of two and more decades. Clinical recovery occurred in 23.2% of patients. Immunocorrection methods, such as hemosorption, plasmapheresis, plasmacytopheresis, xenosplenoperfusion, and the use of splenoperfusate raise the efficacy of the operation to 80-90%. The indications and contraindications for glomectomy in patients with bronchial asthma and methods for immunocorrection treatment of patients after glomectomy were developed.
Subject(s)
Asthma/surgery , Carotid Body/surgery , Anesthesia, Local , Antigen-Antibody Complex/immunology , Asthma/immunology , Asthma/physiopathology , Contraindications , Follow-Up Studies , Hemodynamics , Humans , Immunoglobulin E/immunology , Immunoglobulin G/immunology , Postoperative Care , Preoperative Care , Respiration , Severity of Illness Index , Sorption Detoxification/methods , Surgical Procedures, OperativeABSTRACT
Plasmapheresis was used in 9 patients and plasmacytapheresis in 27 patients with bronchial asthma. This was in 35 patients preceded by glomectomy. Inefficiency of the operation, presence of immunological changes was the basis for the apheresis procedures. No serious complications were observed. Both methods further the elimination of immune complexes. The treatment was positive in 33 of the 36 patients.
