ABSTRACT
Morphological investigation for studying of a local impact on the tissues, localized in the antiseptic textile implantation zone, was conducted. The textile was impregnated by composition of decametoxine with modified polysaccharides. Basing on the investigation result there was established the absence of a toxic impact of antiseptic medical textile on the macroorganism tissues, the regenerative processes course, the wounds epithelization, antioedematous and anti-inflammatory effects.
Subject(s)
Anti-Infective Agents, Local/pharmacology , Decamethonium Compounds/pharmacology , Sutures , Wound Healing/drug effects , Wounds, Penetrating/surgery , Animals , Fibroblasts/drug effects , Lymphocytes/drug effects , Macrophages/drug effects , Male , Monocytes/drug effects , Rats , TextilesABSTRACT
Acute purulent affection of soft tissues is revealing in 8.8-14% patients in the general surgery hospitals. Hospital strains of microbes of an acute surgical infection are highly sensitive toward preparations of surface--active substances, of which antiseptics on the decametoxine background have the highest antimicrobic activity. In 934 patients after surgical treatment of purulent wound the application of decametoxine and preparations on its background had promoted the treatment duration considerable decrease comparing the effect of the other antiseptics.
