1.
Patol Fiziol Eksp Ter
; (2): 11-2, 2003.
Article
in Russian
| MEDLINE
| ID: mdl-12838764
ABSTRACT
Endometriosis is the growth of endometrial tissue outside the uterus. A rat model of endometriosis was used to evaluate the potential for surgical invasions. Experimental endometriosis in albino female rats was induced by autotransplantation of the uterine endometrium to the peritoneum near the ovary. In all the rats endometrial implants developed into endometriotic tissues. The reproductive function and phagocytic activity of peritoneal macrophages were assessed. Rats with endometriosis had longer diestrus and estrous cycle. Increased number of peritoneal macrophages and enhancement of their adhesion and phagocytic activity were registered.