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Biotechnology (N Y) ; 8(6): 547-9, 1990 Jun.
Article in English | MEDLINE | ID: mdl-1366469

ABSTRACT

Crystallization methods for proteins have been the subject of decades of development yet protein crystallization remains the limiting step in structural studies. We present here a new method for protein crystallization--based on the use of high pressure--that enabled us to accelerate dramatically the growth of glucose isomerase crystals. We think this method may have a more general utility.


Subject(s)
Aldose-Ketose Isomerases , Crystallization , Proteins , Carbohydrate Epimerases/biosynthesis , Carbohydrate Epimerases/genetics , X-Ray Diffraction
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