ABSTRACT
The maintenance of quality of life in patients with high-grade glioma is an important endpoint during treatment, particularly in those with glioblastoma multiforme, given its dismal prognosis; thus, the primary aims of treatments are to reduce morbidity, restore or preserve neurological functions, and the capacity to perform daily activities. This review aims to summarise what is currently known about neurocognitive outcome and quality of life in patients with high-grade glioma, particularly in glioblastoma patients. We considered all the variables that can influence neurocognitive functions, the perception of quality of life and their role as predictors for treatment outcomes.
Subject(s)
Brain Neoplasms/psychology , Cognition , Cognitive Dysfunction/psychology , Glioblastoma/psychology , Health Status , Quality of Life/psychology , Brain Neoplasms/physiopathology , Brain Neoplasms/therapy , Cognitive Dysfunction/physiopathology , Glioblastoma/physiopathology , Glioblastoma/therapy , Humans , Prognosis , Treatment OutcomeABSTRACT
Disease prognosis is very poor in patients with brain tumors. Cognitive deficits due to disease or due to its treatment have an important weight on the quality of life of patients and caregivers. Studies often take into account quality of life as a fundamental element in the management of disease and interventions have been developed for cognitive rehabilitation of neuropsychological deficits with the aim of improving the quality of life and daily-life autonomy of patients. In this literature review, we will consider the published studies of cognitive rehabilitation over the past 20 years.
