ABSTRACT
OBJECTIVE: To explore the effect of refined management in the operation room on promoting postoperative recovery in patients undergoing sinusitis surgery via nasal endoscopy. METHODS: In this retrospective study, the clinical data of 80 patients undergoing endoscopic sinus surgery were divided into study group (SG) and control group (CG) according to different nursing methods, with 40 cases in each group. The CG only received routine nursing, while the SG adopted refined management in addition to routine nursing. Postoperative pain, depression, anxiety, and nursing satisfaction were compared between the two groups. RESULTS: There was no significant difference in Visual Analogue Scale (VAS) score between the two groups before operation (P>0.05). After operation, VAS of the SG (1.05±0.24) was significantly better than that of the CG (2.39±0.45), the nursing satisfaction rate of the SG (92.5%) was higher than that of the CG (65.0%), and the overall effective rate of nursing in the SG (95.0%) was higher than that of the CG (77.5%) (all P<0.05). The patients of SG had a lower rate of postoperative complications than CG patients (P<0.05). The operation time and postoperative recovery time of the SG were shorter than those of the CG, and the intraoperative blood loss was less than that of the CG. Smoking history, family history, dust mite allergy, pollen allergy, pet keeping, opening air conditioner use, airing of bed linen, and window ventilation were the main prognostic factors of patients with sinusitis (P<0.05). Family history, duration of immunotherapy, gender and complications were the factors affecting the prognosis of patients with sinusitis (P<0.05). The incidence of depression and anxiety in the SG were lower than those in the CG (P<0.05). The postoperative quality of life in the SG was better than that in the CG (P<0.05). CONCLUSION: Refined nursing can effectively alleviate pain, improve patients' satisfaction of nursing, and also significantly improve patient's depression and anxiety in endoscopic sinus surgery.
ABSTRACT
BACKGROUND: Lung cancers arising in never smokers have been suggested to be substantially different from lung cancers in smokers at an epidemiological, genetic and molecular level. Focusing on non-small cell lung cancer (NSCLC), we characterized lung cancer patients in China looking for demographic and clinical differences between the smoking and never-smoking subgroups. METHODS: In total, 891 patients with NSCLC, including 841 with adenocarcinoma and 50 with squamous cell carcinoma, were recruited in this study. Association of smoking status with demographic and clinical features of NSCLC was determined, and risk factors for lymph node metastasis and TNM stage were evaluated using Multivariate logistic regression analysis. RESULTS: In patients with adenocarcinoma, never smokers showed a younger age at diagnosis (54.2 ± 12.7vs. 59.3 ± 9.4, padjusted<0.001), a lower risk for lymph node metastasis than smokers (7,6% vs. 19.5%, padjusted<0.001) and less severe disease as indicated by lower percentages of patients with TNM stage of III or IV (5.5% vs. 14.7%, padjusted<0.001 ). By contrast, these associations were not observed in 50 patients with squamous cell carcinoma. Multivariate logistic regression analysis showed that smoking status was a risk factor for lymph node metastasis (OR = 2.70, 95% CI: 1.39-5.31, p = 0.004) but not for TNM stage (OR = 1.18, 95% CI: 0.09-14.43, p = 0.896) in adenocarcinoma. CONCLUSION: This study demonstrates that lung adenocarcinoma in never smokers significantly differ from those in smokers regarding both age at diagnosis and risk of lymph node metastasis, supporting the notion that they are distinct entries with different etiology and pathogenesis.
