ABSTRACT
Since the essentiality of boron (B) to plant growth was reported nearly one century ago, the implication of B in physiological performance, productivity and quality of agricultural products, and the morphogenesis of apical meristem in plants has widely been studied. B stresses (B deficiency and toxicity), which lead to atrophy of canopy and deterioration of Citrus fruits, have long been discovered in citrus orchards. This paper reviews the research progress of B stresses on Citrus growth, photosynthesis, light use efficiency, nutrient absorption, organic acid metabolism, sugar metabolism and relocation, and antioxidant system. Moreover, the beneficial effects of B on plant stress tolerance and further research in this area were also discussed.
ABSTRACT
Effluents from wastewater treatment plants contain a mixture of estrogens (MIX: 17ß-estradiol: E2, estrone: E1, estriol: E3 and 17α-ethinylestradiol EE2). High doses of estrogens have been shown to negatively impact fetal testicular development, but the impact of low doses of estrogens in mixture have yet to be elucidated. Using an organ culture system in which embryonic 15.5 day-old rat testes were grown ex vivo, we showed that exposure to the MIX at environmentally relevant concentrations reduces testis growth. No effect was observed on testosterone secretion, but we quantified a significant decrease in the number of Sertoli cells and gonocytes because of higher rates of apoptosis. As ozone (O3) can be used as a disinfectant during wastewater treatment, we confirmed by HPLC-MS analysis that it removes the four parent compounds. Interestingly, the negative effects of the MIX were not observed when testes were exposed to the MIX treated with O3.
Subject(s)
Disinfectants/chemistry , Estrogens/toxicity , Organogenesis/drug effects , Ozone/chemistry , Testis/drug effects , Wastewater , Water Pollutants, Chemical/toxicity , Water Purification/methods , Animals , Apoptosis/drug effects , Chromatography, High Pressure Liquid , Estrogens/chemistry , Female , Leydig Cells/drug effects , Leydig Cells/pathology , Male , Mass Spectrometry , Organ Culture Techniques , Pregnancy , Rats, Sprague-Dawley , Sertoli Cells/drug effects , Sertoli Cells/pathology , Testis/embryology , Water Pollutants, Chemical/chemistryABSTRACT
To date, a great number of studies have demonstrated that altered expression of kinesins is associated with development and progression of various human cancers. Kinesin family member 26B (KIF26B), a member of the kinesin superfamily proteins (KIFs), is essential for kidney development. However, the role of KIF26B during tumorigenesis and progression is limited. Here, we demonstrate that both KIF26B mRNA and protein are overexpression in breast cancer tissues by RT-qPCR and western blot. Immunohistochemistry revealed that KIF26B expression significantly correlated with clinicopathological factors, including tumor size (Pâ=â0.011), grade (Pâ=â0.017), lymph node status (Pâ=â0.009) and ER status (Pâ=â0.012). Moreover, the Kaplan-Meier analysis indicated that breast cancer patients with high KIF26B expression had a shorter survival than those with low KIF26B expression. In addition, multivariate analysis indicated that KIF26B is an independent prognostic for outcome in breast cancer (HR, 2.356; 95%CI, 1.268-4.378; Pâ=â0.007). Collectively, our study demonstrated that KIF26B was overexpression in breast cancer and could be served as a potential prognostic marker.
Subject(s)
Biomarkers, Tumor/genetics , Breast Neoplasms/genetics , Gene Expression , Kinesins/genetics , RNA, Messenger/genetics , Aged , Breast Neoplasms/mortality , Breast Neoplasms/pathology , Disease Progression , Female , Humans , Kaplan-Meier Estimate , Lymphatic Metastasis , Middle Aged , Neoplasm Grading , PrognosisABSTRACT
OBJECTIVE: To evaluate the therapeutic effect and applying value of Hegu (LI 4) for inertia of uterus. METHODS: In three centers, 276 cases enrolled were randomly assigned to a western medicine group and an acupuncture and western medicine group. The western medicine group were treated with intravenous drip of oxytocin, and the acupuncture and western medicine group were treated with electroacupuncture at Hego (LI 4) and intravenous drip of oxytocin. Changes of inertia of uterus and duration and interval of uterine contraction were investigated in the two groups. RESULTS: The total effective rate was 97.1% in the acupuncture group, and 70.3% in the western medicine group with a very significant difference between the two groups (P < 0. 01). There was a significant difference in the duration and the interval of uterine contraction between the two groups (P < 0.1, P < 0.05). CONCLUSION: Elecoroacupuncture at Hego (LI 4) can be adopted for treatment of dystocia due to abnormality of force of labor.
Subject(s)
Acupuncture Points , Electroacupuncture/methods , Labor, Obstetric/physiology , Uterine Contraction , Adult , Female , Humans , Pregnancy , Time FactorsABSTRACT
A fetal/maternal multi-parameter monitor is introduced here in the paper. It can monitor the vital signs of a fetus and his/her mother in a same screen synchronously. It is more useful in obstetric clinics. Its other functions include management of patient file, computer-assistant analyses.
