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1.
Arthrosc Tech ; 13(2): 102858, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38435254

ABSTRACT

Arthroscopic repair of chronic retracted rotator cuff tears remains challenging to shoulder arthroscopy surgeons. With the recent technical advances, most of the massive rotator cuff tears are managed successfully. The biceps tendon is highly vascular and a rich source of tenocytes and fibroblasts, which can promote biological healing. In massive degenerate rotator cuff tears in which the rotator cuff tissue can be released and fixed onto the footprint without much tissue tension, long head of the biceps tendon can act as an augment providing structural support to the poor-quality rotator cuff tissue and also enhancing the healing process. In this Technical Note, we describe arthroscopic rotator cuff repair using biceps augmentation for a massive degenerate rotator cuff tear with the excursion of the cuff onto the footprint with minimal tissue tension.

3.
Tissue Eng Regen Med ; 18(6): 1009-1020, 2021 12.
Article in English | MEDLINE | ID: mdl-34387852

ABSTRACT

BACKGROUND: After surgical repair of chronic rotator cuff tears, healing of the repaired tendons often fails and is accompanied by high-level fatty degeneration. Our purpose was to explore the effects of polydeoxyribonucleotide (PDRN) and polynucleotide (PN) on tendon healing and the reversal of fatty degeneration in a chronic rotator cuff tear model using a rat infraspinatus. METHODS: Sixty rats were randomly assigned to the following three groups (20 rats per group: 12 for histological evaluation and 8 for mechanical testing): saline + repair (SR), PDRN + repair (PR), and PN + repair (PNR). The right shoulder was used for experimental intervention, and the left served as a control. Four weeks after detaching the infraspinatus, the torn tendon was repaired. Saline, PDRN, and PN were applied to the repair sites. Histological evaluation was performed 3 and 6 weeks after repair and biomechanical analysis was performed at 6 weeks. RESULTS: Three weeks after repair, the PR and PNR groups had more CD168-stained cells than the SR group. The PR group showed a larger cross-sectional area (CSA) of muscle fibers than the SR and PNR groups. Six weeks after repair, the PR and PNR groups showed more adipose cells, less CD68-stained cells, and more parallel tendon collagen fibers than the SR group. The PR group had more CD 68-stained cells than the PNR group. The PR group showed a larger CSA than the SR group. The mean load-to-failure values of the PR and PNR groups were higher than that of the SR group, although these differences were not significant. CONCLUSION: PDRN and PN may improve tendon healing and decrease fatty degeneration after cuff repair.


Subject(s)
Polydeoxyribonucleotides , Polynucleotides , Animals , Disease Models, Animal , Polydeoxyribonucleotides/pharmacology , Polydeoxyribonucleotides/therapeutic use , Polynucleotides/pharmacology , Rats , Tendons/pathology , Wound Healing
4.
J Arthroplasty ; 30(12): 2304-7, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26154570

ABSTRACT

This study was to identify the risk factors of heterotopic ossification (HO) after total hip arthroplasty (THA) in ankylosing spondylitis. We analyzed 47 hips (24 patients) with ankylosing spondylitis that underwent primary THA. The incidence of HO was 14.9%. The risk factors were divided into modifiable and nonmodifiable factors. Female gender (P=0.008), preoperative ankylosed hip (P<0.001), occurrence of HO in previous surgery (P=0.036) were nonmodifiable risk factors which increased the prevalence of HO. Of the various modifiable risk factors, elevated preoperative ESR (P=0.007), elevated preoperative CRP (P=0.004) and prolonged duration of surgery (P=0.014) were associated with increased occurrence of HO. Perioperative medical intervention to reduce inflammation (ESR and CRP) may help to decrease HO.


Subject(s)
Arthroplasty, Replacement, Hip/adverse effects , Ossification, Heterotopic/diagnostic imaging , Spondylitis, Ankylosing/surgery , Adult , Female , Hip Joint/diagnostic imaging , Hip Joint/surgery , Hip Prosthesis/adverse effects , Humans , Male , Middle Aged , Ossification, Heterotopic/etiology , Radiography , Retrospective Studies , Risk Factors , Spondylitis, Ankylosing/complications , Young Adult
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