ABSTRACT
Altered function of maternal platelets has been evidenced in intrauterine growth restriction (IUGR) but intraplatelet burden of trace elements, factors known to affect platelet activity, remains unknown in IUGR pregnancy. This study assessed the intraplatelet status of Ca, Cu, Mg, Na, K, P, Zn and their ratios (Ca/P, Ca/Mg, Na/K, Cu/Zn) in IUGR pregnancy (nâ¯=â¯35), uncomplicated pregnancy (nâ¯=â¯25) and in non-pregnant females (nâ¯=â¯25). The IUGR group was characterized by the lowest content of Ca, Mg and Zn, and Ca/P ratio (<1.0), and the highest Ca/Mg and Cu/Zn ratios. The studied parameters in non-pregnant women and in uncomplicated pregnancy were comparable except P content and Ca/Mg ratio which were significantly lower in the former group. No differences in Na and K contents, and Na/K ratio between studied groups were found. This study reports that maternal intraplatelet status of selected minerals may be altered in IUGR.
Subject(s)
Blood Platelets/metabolism , Fetal Growth Retardation/blood , Trace Elements/blood , Adult , Calcium/blood , Case-Control Studies , Female , Gestational Age , Humans , Magnesium/blood , Phosphorus/blood , Platelet Count , Pregnancy , Zinc/bloodABSTRACT
Embryonal rhabdomyosarcoma, a malignant soft tissue neoplasm, is 1 of the most common pediatric tumors of the vagina. Although radical surgery has been replaced with radiation therapy, chemotherapy, and conservative surgery, the use of vaginoscopy is still uncommon. We present the case of an infant who underwent vaginoscopic resection because of botryoid sarcoma at 9 months of age.
