ABSTRACT
Drug-induced osteoporosis is a significant health problem and many physicians are unaware that many commonly prescribed medications contribute to significant bone loss and fractures. In addition to glucocorticoids, proton pump inhibitors, selective serotonin receptor inhibitors, thiazolidinediones, anticonvulsants, medroxyprogesterone acetate, aromatase inhibitors, androgen deprivation therapy, heparin, calcineurin inhibitors, and some chemotherapies have deleterious effects on bone health. Furthermore, many patients are treated with combinations of these medications, possibly compounding the harmful effects of these drugs. Increasing physician awareness of these side effects will allow for monitoring of bone health and therapeutic interventions to prevent or treat drug-induced osteoporosis.
ABSTRACT
Although Staphylococcus aureus can cause a variety of infections, involvement of the biliary tract is rare. We present a middle-aged Caucasian woman who presented with methicillin-resistant S aureus (MRSA) bacteraemia. Subsequent investigation revealed a diagnosis of acute cholecystitis with MRSA-positive specimen cultures. The patient showed clinical improvement after vancomycin therapy and laparoscopic cholecystectomy. This case adds to the growing list of infections that can be attributed to MRSA.
