ABSTRACT
Shaliparni is one of the Laghupanchamoola ingredients. Desmodium gangeticum DC. is an accepted source of Shaliparni as per Ayurvedic Pharmacopoea of India (API). Desmodium laxiflorum DC. is the drug commonly used instead of D. gangeticum in the Saurashtra region. The study is an attempt to compare the above said two species on the basis of their pharmacognostical profiles. The macroscopy and microscopy of roots of both plants were studied as per standard procedures. Root powders of both Desmodium species used in the experimental study to ascertain its Rasa by dilution method. Both the species show the same Rasa and Anurasa i.e., Madhura and Kashaya and almost same morphological and microscopical characters like prismatic crystals, starch grains etc. Hence it is concluded that D. laxiflorum may be considered as a substitute for D. gangeticum on the basis of present pharmacognostical study.
ABSTRACT
Linaria ramosissima (Wall.) Janch., Scrophulariaceae, a folklore plant, has been claimed for its diuretic activities by traditional practitioners. The present study was undertaken to investigate the diuretic activity of L. ramosissima leaves in albino rats. Suspension of leaf powder in 2% gum acacia was administered to experimental rats orally at doses of 450 mg/kg. The diuretic effect was evaluated by measuring the urine volume, pH of urine, and urinary electrolyte excretion. Administration of the test drug increased the urine volume in a non-significant manner, while it enhanced the urinary excretion of sodium, chloride, and potassium significantly, in comparison to the control group. From the present study it can be concluded that the leaves of L. ramosissima have a significant diuretic activity.
ABSTRACT
Tulasi Amla Yashti Ghrita is an Ayurvedic formulation, which is beneficial in the management of the side effects of Head and Neck Malignancies induced by Radiotherapy and Chemotherapy. A pharmacognostical study involving both the macroscopic and powder microscopy of raw drugs of Tulasi Amla Yashti Ghrita and a physicochemical analysis of the finished product were carried out, to evaluate the quality of the formulation. The specific gravity of the formulation was 0.9130 and pH was 3.5. Thin layer chromatography (TLC) and high performance thin layer chromatography (HPTLC) were carried out after organizing the appropriate solvent system, in which five spots were distinguished in TLC and nine spots in HPTLC. Most of the Rf values for the spots observed were identical. The observations could be considered to be the reference standards in future studies.
