Evaluación de un programa de intervención motivacional de actividad física en el tratamiento de la obesidad y el sobrepeso / Evaluation of a motivational intervention of physical activity program in the treatment of obesity and overweight

Objetivo: Analizar la evolución de un programa de actividad física motivada para el tratamiento de la obesidad. Método: Estudio casos-control longitudinal, aleatorizado y controlado, con 2 brazos, 12 meses de seguimiento y una ratio de asignación 1:1. La recogida de datos se hizo entre julio del 2017 y julio del 2018. Los pacientes, mujeres y varones, debían haber sido derivados por sus médicos de empresa con el diagnóstico de sobrepeso u obesidad y una edad entre 20 y 65 años. Se analizan parámetros antropométricos, lipídicos y de seguimiento del programa. Resultados: Han participado 123 pacientes obesos o con sobrepeso (61 en el grupo de intervención [G1] y 62 en el grupo control usual care [G2]), 107 de los cuales han finalizado el estudio (60 en G1 y 47 en G2). Edad media: 45,55±12,83 DE. Sexo: 57,2% mujeres y 42,8% hombres. El seguimiento de los pacientes en el programa es muy superior al grupo control y los abandonos son no significativos (solo hubo uno). Se puede observar que tanto el peso como el índice de masa corporal como los principales parámetros lipídicos se reducen en el grupo de estudio de forma significativa con respecto al grupo control. La actividad física del grupo con intervención de programa de actividad física motivada es 3 veces superior al grupo sin intervención. Se aprecia una relación significativa entre el aumento de la actividad y la reducción de peso (p < 0,001), y también entre esta y la reducción de colesterol y triglicéridos. Conclusiones: En nuestro estudio, un programa de motivación para la actividad física resulta tener más seguimiento y por tanto mejora los parámetros antropométricos y lipídicos

Objective: To analyse the outcomes of a motivational physical activity program for the treatment of obesity. Method: A randomised, controlled, double blind clinical trial with 2 arms, 12 months of follow-up and a 1:1 allocation ratio. The data was collected between July 2017 and July 2018. The patients, of both genders, had to be referred by their occupational medicine doctors with the diagnosis of overweight or obesity and be aged between 20 and 65 years. An analysis was made of the anthropometric measurements, lipid parameters, as well as on the follow-up of the program. Results: A total of 123 obese or overweight patients participated. Two groups were formed; 61 in intervention group [G1] and 62 in as usual care control group [G2]). As regards the 107 that finished the study (60 in G1 and 47 in G2), the mean age was 45.55±12.83 SD, with 57.2% women and 42.8% men. The number of patients followed-up was much higher in the Physical Activity Program than in the control group, and the number of dropouts (only one) was insignificant. It can be seen how both the weight and the body mass index as the main lipid parameters are reduced in the study group significantly with respect to the control group. The physical activity of the group in the motivated physical activity program is three times higher than in the group without intervention. There was a significant relationship between the increase in activity and weight reduction (P<.001), also between the reduction in weight and the reduction in cholesterol and triglycerides. Conclusions: In our study, a motivational physical activity program leads to more follow-up and therefore improves the anthropometric and lipid parameters

[Evaluation of a motivational intervention of physical activity program in the treatment of obesity and overweight]. / Evaluación de un programa de intervención motivacional de actividad física en el tratamiento de la obesidad y el sobrepeso.

OBJECTIVE: To analyse the outcomes of a motivational physical activity program for the treatment of obesity. METHOD: A randomised, controlled, double blind clinical trial with 2 arms, 12 months of follow-up and a 1:1 allocation ratio. The data was collected between July 2017 and July 2018. The patients, of both genders, had to be referred by their occupational medicine doctors with the diagnosis of overweight or obesity and be aged between 20 and 65 years. An analysis was made of the anthropometric measurements, lipid parameters, as well as on the follow-up of the program. RESULTS: A total of 123 obese or overweight patients participated. Two groups were formed; 61 in intervention group [G1] and 62 in as usual care control group [G2]). As regards the 107 that finished the study (60 in G1 and 47 in G2), the mean age was 45.55±12.83 SD, with 57.2% women and 42.8% men. The number of patients followed-up was much higher in the Physical Activity Program than in the control group, and the number of dropouts (only one) was insignificant. It can be seen how both the weight and the body mass index as the main lipid parameters are reduced in the study group significantly with respect to the control group. The physical activity of the group in the motivated physical activity program is three times higher than in the group without intervention. There was a significant relationship between the increase in activity and weight reduction (P<.001), also between the reduction in weight and the reduction in cholesterol and triglycerides. CONCLUSIONS: In our study, a motivational physical activity program leads to more follow-up and therefore improves the anthropometric and lipid parameters.

Effectiveness of the Medtep Hemophilia online platform for adherence to prophylactic treatment in haemophilia patients: Results from a 1-year observational study.

INTRODUCTION: Medtep Hemophilia platform is an online tool that allows patients with congenital coagulopathies to keep track of their daily condition-related events with the objective of ensuring successful adherence to therapy. AIM: To assess the effectiveness of Medtep Hemophilia in improving adherence to prophylactic treatment in haemophilia A and B patients in a 1-year prospective observational study, as well as its impact on the patient's disease status. METHODS: Patients (>13 years old) received support material to familiarize themselves with Medtep Hemophilia. Adherence to treatment, quality of life (QoL) and illness perception were assessed. Values at baseline, 1, 6 and 12 months, and changes from baseline value were analysed. The Hemophilia Joint Health Score (HJHS) test was applied at baseline and study completion. RESULTS: Forty-six patients were enrolled (43 evaluable). After 1 year, 56.4% patients showed continued use of the platform (100% compliance) whereas 25.6% were inactive. Treatment adherence increased both significantly (P < .001) and progressively during the study. Similarly, improved QoL and illness perception were observed with respect to baseline in most of the questionnaire components (P < .05 after 12 months). A patient's age had no influence on the results, whereas compliant patients (>80% of platform use) tended to score better than noncompliant. The HJHS test values remained similar during the study. CONCLUSION: The Medtep Hemophilia online platform helped the studied patients with haemophilia to improve their adherence to prophylactic treatment, while increasing their QoL and illness perception, as well as joint arthropathies stabilization.

[Analysis of clinical relevance applied to 3methods of reducing weight in overweight or obesity followed-up for one year]. / Análisis de relevancia clínica aplicado a 3métodos de reducción de peso en pacientes con sobrepeso u obesidad seguidos durante un año.

OBJECTIVE: To analyse the effect of the use/implementation of 3methods to reduce weight in overweight or obese patients during one year of follow up. MATERIAL AND METHODS: The design corresponds to a double-blind, randomised, controlled clinical trial with 3arms, and 12 months of follow-up. Patients were randomised into 3intervention groups: obesity motivational intervention, with a nurse previously trained in motivational intervention by expert psychologists (G1; n=60); lower intensity consultation, non-motivational group, with digital platform support (G2; N=61), and a third group that received recommendations for weight loss and follow-up in Primary Care Clinic (G3; n=59). Anthropometric variables (weight, height, and abdominal-waist circumference) were measured, and the percentage of patients who managed to reduce their weight ≥5% was considered as the main measurement of treatment effectiveness. RESULTS: All groups significantly decreased body weight at the end of the study, with a reduction in G1 (-5.6kg) followed by G2 (-4.3kg), and G3 (-1.7kg), with an overall mean: -3.9kg. The indicators of clinical relevance were in G1/G3: relative risk (RR): 4.99 (95% CI: from 2.71 to 9.18); relative risk reduction (RRR): 399.1% (171.3 to 818.0); Absolute risk reduction (RAR): 65.3% (from 51.5 to 79.1) and NNT: 2 (from 2 to 2). In the G2/G3 groups: RR: 3.01 (from 1.57 to 5.76); RRR: 200.5% (from 57.0 to 475.5); RAR: 32.8% (from 16.9 to 48.7) and NNT: 4 (from 3 to 6). In the G1/G2 groups: RR: 1.66 (from 1.25 to 2.20); RRR: 66.1% (from 25.3 to 120.1); RAR: 32.5% (from 16.6 to 48.4) and NNT: 4 (from 3 to 7). CONCLUSIONS: All 3groups were able to reduce weight. Although the group with motivational intervention achieved the greatest decrease, as well as the most favourable clinical relevance indicators.

Nutrición e inversión en salud: microbioma y probióticos (los probióticos en la prevención y el tratamiento de enfermedades pediátricas; evidencias científicas) / Nutrition and investment: microbiome and probiotics (probiotics in prevention and treatment of pediatric conditions; scientific evidence)

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