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1.
J Am Vet Med Assoc ; 214(4): 529-31, 1999 Feb 15.
Article in English | MEDLINE | ID: mdl-10029857

ABSTRACT

OBJECTIVE: To evaluate the effect of a single dose of recombinant bovine somatotropin (bST) on certain metabolic values, health, and milk production of dairy cows undergoing surgery for left displacement of the abomasum. DESIGN: Blinded clinical trial. ANIMALS: 413 cows with left displacement of the abomasum. PROCEDURE: A single 500-mg dose of bST was administered to dairy cows following surgery in field practice conditions for left displacement of the abomasum. A placebo of the same carrier without bST was administered to control cows in this blinded study. Metabolic and production responses in a short-term follow-up period were measured. RESULTS: Blood glucose concentrations in cows 3 to 5 days after surgery were statistically higher for treated cows than for control cows. A higher proportion of treated cows had improved urine ketone test results than did controls. Significant differences in other metabolic values, health, and milk production were not detected. CLINICAL IMPLICATIONS: Treatment of metabolically compromised cows with bST may have some positive effects, but further investigation is needed to confirm therapeutic value.


Subject(s)
Abomasum , Cattle Diseases/drug therapy , Cattle Diseases/surgery , Growth Hormone/therapeutic use , Ketosis/veterinary , Stomach Diseases/veterinary , Abomasum/surgery , Animals , Blood Glucose/analysis , Cattle , Female , Growth Hormone/blood , Ketone Bodies/urine , Ketosis/drug therapy , Ketosis/etiology , Recombinant Proteins/therapeutic use , Risk Factors , Stomach Diseases/complications , Stomach Diseases/surgery
2.
J Dairy Sci ; 78(7): 1477-88, 1995 Jul.
Article in English | MEDLINE | ID: mdl-7593841

ABSTRACT

This study compared three programs for reproductive management of the postpartum period for reproductive performance and net economic benefit within three dairy herds (n = 1624 cows). Cows on one program received PGF alpha injection at 25 to 32 d postpartum for reproductive therapy, and cows on a second program received additional PGF2 alpha at 39 to 46 d postpartum for synchronization of estrus. These programs were compared with a postpartum program of rectal palpation based on veterinary intervention. Survival analysis indicated that cows receiving PGF2 alpha for reproductive therapy and synchronization of estrus had an 11% higher rate of first AI and 10% higher rate of pregnancy than did cows receiving the rectal palpation. No differences existed between the cows receiving rectal palpation and those receiving the PGF2 alpha. Because overall conception rates and conception rates at first AI did not differ among programs, the improved reproductive performance of cows receiving PGF2 alpha for both therapy and synchronization may be attributed to greater synchronization of estrus, which resulted in improved estrus detection. A partial budget indicated that the PGF2 alpha programs were less expensive than the rectal palpation program. When PGF2 alpha was used for postpartum reproductive therapy and synchronization of estrus, reproductive performance and net economic benefit were increased compared with those of the other programs.


Subject(s)
Cattle/physiology , Dinoprost/pharmacology , Lactation , Postpartum Period , Reproduction/drug effects , Animals , Dairying/methods , Dinoprost/administration & dosage , Estrus/drug effects , Female , Palpation , Pregnancy , Rectum , Reproductive Techniques/veterinary
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