ABSTRACT
The aim of this study was to assess the prevalence of hypodontia in subjects with Down's syndrome. A group of 112 subjects with cytogenetically confirmed diagnosis of Down's syndrome, aged 12-36 years were examined. Hypodontia of the permanent teeth has been established on the basis of dental examination and orthopantomogram analysis in all cases. Hypodontia was present in 38.6% patients. Upper lateral incisors were most commonly missing. In patients with Angle class I, hypodontia most frequently referred to upper left lateral incisors, upper left first premolars and lower left second premolars. In patients with Angle class II, lower second premolars and upper incisors were most commonly affected by hypodontia. In patients with Angle class III, hypodontic findings more frequently referred to the maxilla as compared to mandible.