ABSTRACT
PURPOSE: This validation study was designed to assess the psychometric validity and quality of the Polish translation of the EORTC QLQ-LMC21 questionnaire in Polish colorectal patients suffering with liver metastases. METHODS: Patients with either histopathological or imaging confirmation of colorectal cancer with liver metastases, with a minimum of three months survival, were eligible for this study. These patients completed the Polish version of the EORTC core QLQ-C30, the QLQ-LMC21 module, and a demographic data questionnaire. The questionnaires were completed twice, once before undergoing either hepatectomy (n = 63) or palliative treatment (n = 97) and three months after the primary treatment. Standardized analyses of validity and reliability were performed. RESULTS: One hundred and sixty patients were enrolled in this study with the mean age of the hepatectomy group 64.3 ± 14.1 and 66.1 ± 12.7 for the palliative treatment group. The QLQ-LMC21 exhibited positive internal consistency with Cronbach's alpha coefficients ranging from 0.72 to 0.90. The multi-trait scaling analysis demonstrated adequate convergent and discriminant validity. Test-retest reliability was undertaken with 40 patients (25%) with the ICCs for each item ranging from 0.64 to 0.88. The hepatectomy group had a significantly greater Karnofsky Performance Score than the palliative treatment group (p.<0.001). Overall there were weak correlations between the two questionnaires which confirm that the QLQ-LMC21 addresses health issues not assessed in the QLQ-C30. CONCLUSION: The Polish version of the QLQ-LMC21 proved to be a valid and reliable questionnaire to use in conjunction with the QLQ-C30 core questionnaire.
Subject(s)
Colorectal Neoplasms/psychology , Colorectal Neoplasms/therapy , Liver Neoplasms/psychology , Liver Neoplasms/therapy , Neoplasm Metastasis/therapy , Quality of Life/psychology , Surveys and Questionnaires/standards , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Palliative Care , Poland , Prospective Studies , Psychometrics , Reproducibility of Results , TranslationsABSTRACT
The aim of our study was to undertake a prospective validation study of the Polish version of the EORTC ovarian cancer (EORTC QLQ-OV28) module used together with the EORTC QLQ-C30. The translated module was pilot-tested according to the EORTC guidelines. Patients with histological confirmation of ovarian cancer were eligible for the study. All patients filled out the Polish version of the EORTC QLQ-OV28, the EORTC QLQ-C30 and a demographic questionnaire. Standard validity and reliability analyses were performed. One-hundred and forty patients agreed to take part in the study (mean age ± standard deviation: 63.3 ± 10.2 years). Cronbach's alpha coefficients showed positive internal consistency (0.78-0.91). Interclass correlations for the EORTC QLQ-OV28 ranged from 0.77 to 0.93 and proved appropriate test-retest reliability. Satisfactory convergent and discriminant validity in multi-trait scaling analyses was seen. The Polish version of the EORTC QLQ-OV28 module proved to be a reliable and valid tool for measuring health-related quality of life in patients with ovarian cancer.
Subject(s)
Ovarian Neoplasms/pathology , Quality of Life , Surveys and Questionnaires , Aged , Female , Guidelines as Topic , Humans , Middle Aged , Pilot Projects , Poland , Prospective Studies , Reproducibility of ResultsABSTRACT
AIM: The aim of our study was to report preliminary validation data on the EORTC translated, Polish version of the EORTC QLQ-H&N35 questionnaire to show that this tool is an acceptable and psychometrically robust measure to collect HRQoL data in Polish patients with head and neck malignancies. MATERIALS AND METHODS: Patients with histological confirmation of head and neck malignancies were eligible for the study. All patients filled out the Polish version of the EORTC QLQ-H&N35 module in addition to EORTC QLQ-C30 and a demographic questionnaire. Standardized validity and reliability analyses were performed. RESULTS: Fifty-one patients (23 females - 45.1%) were enrolled into the study, with a mean age of 51.3 ± 12.9 years. Cronbach alpha coefficients, range 0.72-0.85, showed positive internal consistency. Satisfactory convergent and discriminant validity in multi-trait scaling analyses was seen. CONCLUSIONS: Basing on the preliminary data from this report, one can say that the Polish version of the EORTC QLQ-H&N35 module is a reliable and valid tool for measuring HRQoL in patients with head and neck malignancies. However further research is needed to establish the full psychometric properties of the described module, especially test-retest and responsiveness over time.
