1.
J Nat Prod
; 64(1): 131-3, 2001 Jan.
Article
in English
| MEDLINE
| ID: mdl-11170688
ABSTRACT
Two new cyclic peroxides (1 and 2) and the known metabolite 3 have been found in the organic extract of the Indian sponge Acarnus bicladotylota. The structure of the new products has been assured by chemical and spectroscopic methods. The absolute stereochemistry of 1-3 has been determined by Mosher's method on the semisynthetic derivative 4.
Subject(s)
Antineoplastic Agents/chemistry , Furans/chemistry , Lactones/chemistry , Peroxides/chemistry , Porifera/chemistry , Animals , Antineoplastic Agents/isolation & purification , India , Magnetic Resonance Spectroscopy , Peroxides/isolation & purification , Spectrophotometry, Infrared
2.
J Nat Prod
; 62(10): 1367-70, 1999 Oct.
Article
in English
| MEDLINE
| ID: mdl-10543894
ABSTRACT
Two new scalaranes (1 and 2) have been isolated from the dorid nudibranch Glossodoris atromarginataand its prey. The structures were deteremined by spectral techniques and confirmed by chemical methods. Compounds 1 and 3 showed selective cytotoxic activity against human thyroid carcinoma.
