1.
Chem Commun (Camb)
; 54(82): 11530-11533, 2018 Oct 11.
Article
in English
| MEDLINE
| ID: mdl-30137112
ABSTRACT
Synthesis of pyrazolo[1,5-c]quinazolines from four easily available precursors is presented through a one-pot tricyclic Pd(ii)/Ag(i) relay catalysis. The bimetallic relay cascade forges five new chemical bonds by concatenating six discrete chemical steps. The relay catalysis enables four-component assembly of pyrazolo[1,5-c]quinazolines that selectively inhibit EGFR, exhibit apoptosis through the ROS-induced mitochondrial-mediated pathway, and arrest the cell cycle at the G1 phase.
2.
Planta Med
; 32(1): 71-5, 1977 Aug.
Article
in English
| MEDLINE
| ID: mdl-905417
3.
Planta Med
; 31(1): 14-6, 1977 Feb.
Article
in English
| MEDLINE
| ID: mdl-840921