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Biofactors ; 45(4): 507-516, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31145514

ABSTRACT

The red blood cell distribution width (RDW) is an index of the heterogeneity of circulating red blood cell size, which along with other standard complete blood count (CBC) parameters are used to identify hematological system diseases. Besides hematological disorders, several clinical studies have shown that an increased in the RDW may be associated with other diseases including acute pancreatitis, chronic kidney disease, gastrointestinal disorders, cancer, and of special interest in this review, cardiovascular disease (CVD). The diagnostic and prognostic value of RDW in different CVD (acute coronary syndrome, ischemic cerebrovascular disease, peripheral artery disease, atrial fibrillation, heart failure, and acute ischemic stroke) has been reviewed in this article, to provide an understanding how its measurement may be applied to improve the management of these conditions.


Subject(s)
Acute Coronary Syndrome/diagnosis , Atrial Fibrillation/diagnosis , Brain Ischemia/diagnosis , Erythrocytes/pathology , Heart Failure/diagnosis , Peripheral Arterial Disease/diagnosis , Stroke/diagnosis , Acute Coronary Syndrome/blood , Atrial Fibrillation/blood , Biomarkers/blood , Brain Ischemia/blood , Erythrocyte Indices , Heart Failure/blood , Humans , Peripheral Arterial Disease/blood , Predictive Value of Tests , Prognosis , Stroke/blood
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