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3.
AJNR Am J Neuroradiol ; 25(4): 631-5, 2004 Apr.
Article in English | MEDLINE | ID: mdl-15090357

ABSTRACT

Basal cell adenoma is a rare benign salivary gland epithelial tumor, usually involving the parotid gland. We report CT and MR findings of three cases with basal cell adenoma occurring in the parotid gland. The three cases presented here demonstrate a well-circumscribed tumor, which showed a cystic and solid, or the pure solid mass. They were well enhanced after contrast matter injection. The solid portion of the mass was isoattenuated at CT, with intermediate signal intensity on T1- and T2-weighted MR images. Its cystic portion was hyperintense on both T1- and T2-weighted MR images. It had a hypointense rim on T2-weighted image.


Subject(s)
Adenoma/diagnosis , Image Processing, Computer-Assisted , Magnetic Resonance Imaging , Parotid Neoplasms/diagnosis , Tomography, X-Ray Computed , Adenoma/pathology , Adenoma/surgery , Biopsy, Needle , Diagnosis, Differential , Female , Humans , Middle Aged , Parotid Gland/pathology , Parotid Gland/surgery , Parotid Neoplasms/pathology , Parotid Neoplasms/surgery
4.
Cyberpsychol Behav ; 6(3): 275-80, 2003 Jun.
Article in English | MEDLINE | ID: mdl-12855083

ABSTRACT

Research has shown that many smokers experience an increase in the desire to smoke when exposed to smoking-related cues. Cue exposure treatment (CET) refers to the manualized, repeated exposure to smoking-related cues, aimed at the reducing cue reactivity by extinction. In this study, we constructed a virtual reality system for evoking a desire of nicotine, which was based on the results of a Questionnaire of Nicotine-craving. And we investigated the effectiveness of the virtual reality system as compared to classical device (pictures). As a result, we reached the conclusion that virtual reality elicits more craving symptoms than the classical devices.


Subject(s)
Cues , Disruptive, Impulse Control, and Conduct Disorders/therapy , Tobacco Use Disorder/psychology , Tobacco Use Disorder/therapy , User-Computer Interface , Visual Perception , Adult , Humans , Male , Surveys and Questionnaires
5.
J Comput Assist Tomogr ; 26(6): 1019-21, 2002.
Article in English | MEDLINE | ID: mdl-12488753

ABSTRACT

Paragonimus westermani is a lung fluke but may be found in organs other than the lungs. A case of omental paragonimiasis was found incidentally by plain radiography and computed tomography and showed multiple, irregularly shaped, conglomerated calcifications in the intraperitoneum. Many P. westermani ova were detected in the resected omentum. This uncommon calcification on the plain abdominal radiography and computed tomography scan was considered to represent radiologic findings of ectopic paragonimiasis.


Subject(s)
Omentum/parasitology , Paragonimiasis/diagnostic imaging , Peritoneal Diseases/parasitology , Calcinosis , Female , Humans , Middle Aged , Omentum/diagnostic imaging , Peritoneal Diseases/diagnostic imaging , Tomography, X-Ray Computed
6.
Drug Dev Ind Pharm ; 28(9): 1125-31, 2002 Oct.
Article in English | MEDLINE | ID: mdl-12455471

ABSTRACT

Matrix-type transdermal delivery systems of testosterone (TS) were formulated with three different pressure-sensitive adhesives (PSA). The effects of PSA, skin permeation enhancers, and solubilizers on the rat skin permeation rate of TS were systematically investigated. Without a solubilizer, the skin permeation rate of TS reached its maximum value when only 2% of TS was loaded in the matrix and the crystal formation in the matrix was very rapid and severe. Two surfactants differing in their hydrophile-lipophile balance (HLB) number were, therefore, considered. Span 80, which was of the lower HLB number, was more effective than Tween 80 in increasing the solubility, and thereby increasing the permeation rate of TS. Moreover, the concentrations of both the solubilizer and the skin permeation enhancer affected the skin permeation rate. Thus, the highest skin permeation rate (4.14 micrograms/cm2/hr) was achieved when 2% TS was loaded in DuroTak 87-2516 together with 10% Span 80 and 3% dodecylamine, the permeation enhancer. In vivo study showed that the application of an experimental patch on rat abdominal skin resulted in a prompt and significantly higher plasma concentration of TS than that of a commercial product (Testoderm) designed to apply on the scrotal skin. The area under the curve (AUC) increased linearly as the loading dose of TS increased up to 6%. Thus, based on these results, a non-scrotal matrix-type transdermal delivery system of TS could be developed.


Subject(s)
Adhesives/chemistry , Skin Absorption/drug effects , Testosterone/pharmacokinetics , Adhesives/pharmacology , Administration, Cutaneous , Amines/pharmacology , Animals , Area Under Curve , Chromatography, High Pressure Liquid , Crystallization , Dose-Response Relationship, Drug , Drug Delivery Systems , Hexoses/pharmacology , Male , Polysorbates/pharmacology , Rats , Rats, Sprague-Dawley , Surface-Active Agents/pharmacology , Testosterone/administration & dosage , Testosterone/blood , Testosterone/chemistry
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