ABSTRACT
Solitary fibrous tumors (SFT) are uncommon mesenchymal tumors. SFT have several synonyms including localized fibrous tumor, benign mesothelioma, localized fibrous mesothelioma, and submesothelial fibroma. SFT usually occur in the pleura or other serosal surfaces, but SFT can also develop in extrapleural areas including the nasal cavity, orbit, retroperitoneum, and pelvis. Cutaneous SFT is extremely rare, and more likely to occur in the head and neck region. Histologically, this tumor can mimic a variety of benign and malignant tumors such as dermatofibroma, dermatofibrosarcoma protuberans, spindle cell lipoma or other mesenchymal tumors. Most cases of SFT show non-aggressive clinical courses, with low recurrence rates. Herein, we describe a case of primary cutaneous SFT which presented with huge mass on the back.
Subject(s)
Cyclopropanes/administration & dosage , Facial Dermatoses/drug therapy , Immunologic Factors/administration & dosage , Immunotherapy/methods , Nail Diseases/drug therapy , Skin/drug effects , Warts/drug therapy , Adolescent , Adult , Child , Cyclopropanes/adverse effects , Drug Administration Schedule , Facial Dermatoses/diagnosis , Facial Dermatoses/immunology , Facial Dermatoses/virology , Female , Humans , Immunologic Factors/adverse effects , Immunotherapy/adverse effects , Male , Nail Diseases/diagnosis , Nail Diseases/immunology , Nail Diseases/virology , Remission Induction , Retrospective Studies , Skin/immunology , Skin/pathology , Skin/virology , Time Factors , Treatment Outcome , Warts/diagnosis , Warts/immunology , Warts/virology , Young AdultABSTRACT
Diphenylcyclopropenone (DPCP) immunotherapy has been shown to be efficacious for the treatment of warts, especially periungual warts for which destructive techniques are limited. However, factors affecting the duration of treatment of periungual warts have not been studied. A total of 61 patients with periungual warts who were completely cured with DPCP immunotherapy were included in this study. Age, sex, disease duration, location (fingernail, toenail, or both), number of warts, diameter of the largest wart, application number for sensitization and two types of sensitization reactions, erythema and blister index (EBI), and pruritus index were evaluated. Multiple linear regression analysis was performed to find correlations of these variables with the treatment duration. Of the nine variables, application number for sensitization (regression coefficient = 3.251 and 2.428, respectively) and EBI (regression coefficient = -9.950 and -9.694, respectively) were independent factors significantly affecting both the total duration of treatment and the duration of treatment after sensitization (p < 0.05, respectively). The sample size was limited. A shorter sensitization period and more severe EBI of the sensitization reaction contribute to a shorter time required for a complete cure in the treatment of periungual warts with DPCP immunotherapy.
