Autoencoder-Based Signal Modulation and Demodulation Methods for Sonobuoy Signal Transmission and Reception.

Sonobuoy is a disposable device that collects underwater acoustic information and is designed to transmit signals collected in a particular area to nearby aircraft or ships and sink to the seabed upon completion of its mission. In a conventional sonobuoy signal transmission and reception system, collected signals are modulated and transmitted using techniques such as frequency division modulation or Gaussian frequency shift keying. They are received and demodulated by an aircraft or a ship. However, this method has the disadvantage of a large amount of information being transmitted and low security due to relatively simple modulation and demodulation methods. Therefore, in this paper, we propose a method that uses an autoencoder to encode a transmission signal into a low-dimensional latent vector to transmit the latent vector to an aircraft or vessel. The method also uses an autoencoder to decode the received latent vector to improve signal security and to reduce the amount of transmission information by approximately a factor of a hundred compared to the conventional method. In addition, a denoising autoencoder, which reduces ambient noises in the reconstructed outputs while maintaining the merit of the proposed autoencoder, is also proposed. To evaluate the performance of the proposed autoencoders, we simulated a bistatic active and a passive sonobuoy environments. As a result of analyzing the sample spectrograms of the reconstructed outputs and mean square errors between original and reconstructed signals, we confirmed that the original signal could be restored from a low-dimensional latent vector by using the proposed autoencoder within approximately 4% errors. Furthermore, we verified that the proposed denoising autoencoder reduces ambient noise successfully by comparing spectrograms and by measuring the overall signal-to-noise ratio and the log-spectral distance of noisy input and reconstructed output signals.

Traumatic and Non-traumatic Osteonecrosis in the Femoral Head of a Rabbit Model.

Osteonecrosis of the femoral head is an idiopathic, debilitating and progressive disease. A number of traumatic or non-traumatic animal models have been reported for research on osteonecrosis. This study was performed to compare the efficacy of femoral head osteonecrosis in rabbits by traumatic and non-traumatic methods. Twenty-seven New Zealand White rabbits were divided into three experimental groups, nine heads each. Two groups were surgically induced into osteonecrosis; a steel cerclage wire was ligated tightly around the neck of the right femoral head (Group W), and the femoral neck was tied with a cerclage wire in the same way as in the W group, and burned by attachment of an electrode tip to the wire and then the wire was removed (Group B). The other group was induced into osteonecrosis with a single intra-muscular injection of 20 mg/kg methyl-prednisolone acetate single injection (Group M). In the control group, the left femoral head of animals in group W and B was used. After two weeks, rabbits were sacrificed and the femoral head and neck were collected. Osteonecrosis of the femoral head was evaluated by radiography, histology and immunohistology methods. Osteonecrosis lesions in the femoral head were identified in traumatic models of groups W and B. Cartilage degeneration in the superficial layer and TUNEL positive cells in the femoral head were detected more in Group B than in Group W. These findings revealed that short-term induced osteonecrosis of the femoral head was effectively achieved by cautery around the femoral neck.

Comparison of the cytotoxic effects of bupivacaine, lidocaine, and mepivacaine in equine articular chondrocytes.

OBJECTIVE: To compare the chondrotoxicity of bupivacaine, lidocaine, and mepivacaine in equine articular chondrocytes in vitro. STUDY DESIGN: Prospective, experimental study. STUDY MATERIAL: Equine articular chondrocytes. METHODS: Primary cultured equine chondrocytes were exposed to 0.5% bupivacaine, 2% lidocaine, or 2% mepivacaine for 30 or 60 minutes. After treatment, cell viability was evaluated by trypan blue exclusion and the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) colorimetric assay in a dose dependent manner. Apoptosis and necrosis of chondrocytes were analyzed with the double staining of Hoechst 33258 and propidium iodide using fluorescence microscopy, and the results were confirmed using flow cytometry. RESULTS: After 30-minute exposure, trypan blue exclusion assay revealed that cell viability of 0.5% bupivacaine group was 28.73±8.44%, and those of 2% lidocaine and 2% mepivacaine were 66.85±6.03% and 86.27±2.00%, respectively. The viability of chondrocytes after saline treatment was 95.95±2.75%. The results of MTT assay and fluorescence microscopy had similar tendency with trypan blue assay. Each result showed that bupivacaine was the most toxic of the three local anaesthetics. Mepivacaine was less toxic than lidocaine. The results of the viability test suggest that bupivacaine and lidocaine exhibit a marked chondrotoxicity, and that this is mainly due to necrosis rather than apoptosis. CONCLUSIONS AND CLINICAL RELEVANCE: Bupivacaine may induce detrimental chondrotoxicity when administered intra-articularly, especially in patients with joint disease, and we suggest that it should be used cautiously in equine practice. Mepivacaine may be an alternative to both bupivacaine and lidocaine.

Comparison of the degree of hip joint luxation induced by the lateral and medial surgical approaches used to generate vascular deprivation-induced necrosis of the femoral head in rats.

UNLABELLED: The rat model that is commonly used to study femoral head osteonecrosis involves the induction of osteonecrosis by surgery employing a lateral approach to the hip joint. However, this approach induces hip joint luxation, which means it is difficult to determine whether the osteonecrosis arises because of the vascular deprivation or because of the hip joint luxation. Whether or not femoral head osteonecrosis can be induced by the medial approach to the hip joint, which does not generate hip joint luxation, was assessed. MATERIALS AND METHODS: twelve 6-month-old F344 rats were subjected to the lateral or medial approach. RESULTS: four weeks after surgery, the lateral approach group showed luxation upon radiography, but the medial approach group did not. Histopathology revealed both groups exhibited osteonecrosis of the femoral head. CONCLUSION: a surgically induced model of femoral head osteonecrosis that employs the medial approach is a more effective model than that using the lateral approach.

Treatment of hydrocephalus with high-pressure valve ventriculoperitoneal shunt in a dog.

A 5-month-old male Maltese with right-sided circling, deafness, and blindness was presented. A diagnosis of communicating hydrocephalus was made. A ventriculoperitoneal shunt was implanted and the cerebrospinal fluid was drained by using an adjustable valve type (Medtronic Strata). The valve was set at 2.5 (135-155 mmH2O). This was done to prevent the possibility of an overdrainage-induced collapse of the brain parenchyma, which can occur rarely when canine hydrocephalus is treated by using a low-pressure valve. Computed tomography performed 6 weeks and 1 year after surgery revealed the ventricles had decreased in size. Thus, a high-pressure valve used during the treatment of hydrocephalus was able to maintain normal intracranial pressure.