Nanograin network memory with reconfigurable percolation paths for synaptic interactions.

The development of memory devices with functions that simultaneously process and store data is required for efficient computation. To achieve this, artificial synaptic devices have been proposed because they can construct hybrid networks with biological neurons and perform neuromorphic computation. However, irreversible aging of these electrical devices causes unavoidable performance degradation. Although several photonic approaches to controlling currents have been suggested, suppression of current levels and switching of analog conductance in a simple photonic manner remain challenging. Here, we demonstrated a nanograin network memory using reconfigurable percolation paths in a single Si nanowire with solid core/porous shell and pure solid core segments. The electrical and photonic control of current percolation paths enabled the analog and reversible adjustment of the persistent current level, exhibiting memory behavior and current suppression in this single nanowire device. In addition, the synaptic behaviors of memory and erasure were demonstrated through potentiation and habituation processes. Photonic habituation was achieved using laser illumination on the porous nanowire shell, with a linear decrease in the postsynaptic current. Furthermore, synaptic elimination was emulated using two adjacent devices interconnected on a single nanowire. Therefore, electrical and photonic reconfiguration of the conductive paths in Si nanograin networks will pave the way for next-generation nanodevice technologies.

All-fiber 6-mode multiplexers based on fiber mode selective couplers.

All-fiber 6-mode multiplexer composed of two consecutive LP11-mode selective couplers (MSC), two LP21-MSCs and an LP02-MSC is fully characterized by wavelength-swept interferometer technique. The MSCs are fabricated by polished-type fiber couplers coupling LP01 mode of a single mode fiber into a higher-order mode of a few mode fiber. A pair of the mode multiplexers has minimum mode dependent loss of 4 dB and high mode group selectivity of over 15 dB. Mode division multiplexed transmission enabled by the all-fiber mode multiplexers is demonstrated over fiber spans of 117 km employing an in-line multi-mode optical amplifier. 6 modes of 120 Gb/s dual polarization quadrature phase shift keying signals combined with 30 wavelength channels are successfully transmitted.

Broadband mode division multiplexer using all-fiber mode selective couplers.

We report an all-fiber mode division multiplexer formed with cascaded mode selective couplers with significantly broadened bandwidth potentially spanning S, C and L band. This was achieved by matching the effective refractive indices over a wide wavelength range for the few mode fiber and the single mode fiber used in the coupler. The multiplexer provides high coupling efficiency (>55% for the worst case) for the 4 spatial modes over the entire wavelength range of 1515-1590 nm. The all-fiber construction provides mechanical stability. Experimental results for the coupling efficiency and the mode extinction ratio for each spatial mode are presented along with the far field radiation patterns.

Automatic detection method of hepatocellular carcinomas using the non-rigid registration method of multi-phase liver CT images.

BACKGROUND: Multi-phase CT images are obtained sequentially after the injection of contrast agents so that there is a large amount of local deformation between images due to the respiratory and heart motion. Therefore, a non-rigid registration technique is required in order to establish the anatomical correspondence between the multi-phase CT images for liver CAD (computer-aided diagnosis). OBJECTIVE: In this paper, we propose the automatic detection method of hepatocellular carcinomas using the non-rigid registration method of multi-phase CT images. METHODS: Global movements between multi-phase CT images are aligned by rigid registration based on normalized mutual information. Local deformations between multi-phase CT images are modeled by non-rigid registration based on B-spline deformable model. After the registration of multi-phase CT images, hepatocellular carcinomas are automatically detected by analyzing the original and subtraction information of the registered multi-phase CT images. RESULTS: We applied our method to twenty five multi-phase CT datasets. Experimental results showed that the multi-phase CT images were accurately aligned. All of the hepatocellular carcinomas including small size ones in our 25 subjects were accurately detected using our method. CONCLUSION: We conclude that our method is useful for detecting hepatocellular carcinomas.

Mode- and wavelength-division multiplexed transmission using all-fiber mode multiplexer based on mode selective couplers.

We propose all-fiber mode multiplexer composed of two consecutive LP11 mode selective couplers that allows for the multiplexing of LP01 mode and two-fold degenerate LP11 modes. We demonstrate WDM transmission of 32 wavelength channels with 100 GHz spacing, each carrying 3 modes of 120 Gb/s polarization division multiplexed quadrature phase shifted keying (PDM-QPSK) signal, over 560 km of few-mode fiber (FMF). Long distance transmission is achieved by 6×6 multiple-input multiple-output digital signal processing and modal differential group delay compensated link of FMF. The all-fiber mode multiplexer has considerable potential to be used in mode- and wavelength-division multiplexed transmission.

Mode division multiplexed optical transmission enabled by all-fiber mode multiplexer.

Mode division multiplexed optical transmission enabled by all-fiber mode multiplexer is investigated. The proposed all-fiber mode multiplexer is composed of consecutive mode selective couplers. It multiplexes or demultiplexes LP01, LP11, LP21, and LP02 modes simultaneously. We demonstrate successful transmission of three spatial modes with 120 Gb/s PDM-QPSK signals over 15 km of four mode fiber by using 6x6 MIMO digital signal processing.

Cervical pedicle screw placement using the "key slot technique": the feasibility and learning curve.

STUDY DESIGN: A retrospective study. OBJECTIVES: To present the accuracy and safety of a novel "key slot (KS)" technique for cervical pedicle screw (CPS) placement with the learning curve. SUMMARY OF BACKGROUND DATA: Safety and learning curve are the issues preventing wide acceptance of CPS. On the basis of the local anatomy of the pedicle, the authors modified the conventional technique to increase the accuracy and comfortableness of CPS placement with minimal bone loss. METHODS: A total of 277 subaxial CPS in 50 patients had been inserted using author's technique were reviewed. The KS-shaped entry was created on the medial half of the lateral mass with a 3 mm cutting burr. The shape of entry was a right-angled triangle on the axial plane. The apex of triangle was the virtual pedicle inlet and the oblique side was same as pedicle axis. After making entry, the pedicle was probed with a curved awl along the medial wall. On the postoperative vascular-enhanced computed tomography scan, we analyzed the direction and grade of pedicle perforation (grade 0: no perforation, 1:< 25%, 2: 20% to 50%, 3: > 50% of screw diameter) on the chronological group of consecutive 10 cases. Grade 2 and 3 were considered as incorrect position. RESULTS: The correct position was found in 250 screws (90.3%); grade 0 - 215 screws, 1 - 35 screws and the incorrect position in 27 screws (9.7%); grade 2 - 21 screws, grade 3 - 6 screws. The incidence of incorrect screw position was 18% in the initial 20 cases and 2.7% after that. There was no neurovascular complication related with CPS. CONCLUSIONS: We performed CPS placement using the KS technique and with 90% correct position without clinical complications. After the learning curve, the incidence was 2.7%. This technique could be considered relatively concrete and safe modification of conventional technique with minimal bone loss.

Ultrawidely tunable single-mode fiber acousto-optic filter.

A single-mode fiber (SMF) acousto-optic tunable filter (AOTF) with a tuning range of more than 300 nm is demonstrated. The SMF used in the experiment has a ring of symmetric holes within the cladding, which causes a larger mode-index difference between the first and the second higher-order antisymmetric modes than those of a conventional SMF. As a result, the difference in beatlengths between the core mode and the higher-order modes is highly increased, which makes it possible for the SMF AOTF to exhibit a single resonance peak in the transmission spectrum over the wavelength range of 1.3-1.6 µm for given acoustic frequencies of 3.1-3.8 MHz.

Adult cor triatriatum presenting as cardioembolic stroke.

Cor triatriatum is a rare congenital cardiac malformation characterized by a fibromuscular membrane that divides the left atrium into two distinct chambers. In almost all cases, it is diagnosed in childhood, whereas adult cases are extremely rare. Herein, we describe an unusual case of cor triatriatum in a 55-year-old woman who presented with embolic cerebral infarction. The patient experienced sudden-onset, transient left-sided homonymous hemianopsia and echocardiography and multidetector computed tomography detected a membrane-like structure across the left atrium, confirming the diagnosis of a cor triatriatum. The laboratory examination for hypercoagulopathy was negative. She was conservatively treated with anticoagulation and her neurological manifestation gradually improved.

[A case of primary leiomyosarcoma of the liver presenting with acute bleeding].

Leiomyosarcoma is a rare tumor of the liver. It usually arises from many other organs including uterus, gastrointestinal tract, retroperitoneum, and soft tissues. Primary hepatic leiomyosarcoma progresses very slowly and is not associated with chronic liver disease. When the tumor is detected early enough to be treated by operation, the prognosis is favorable. While several cases of primary hepatic leiomyosarcoma have been reported in Korea, there was no case associated with acute bleeding. We report a 80-year old male patient with huge primary hepatic leiomyosarcoma, who presented with acute bleeding and IVC obstruction. The patient was treated by embolization and IVC stenting.

A case of primary aldosteronism with end stage renal disease.

A 52-year-old woman was referred to our hospital due to chronic renal failure with a 10-year history of hypertension. We found polycystic kidney disease, pulmonary tuberculosis and an aldosterone-producing adrenocortical mass. At this time, her serum potassium level and blood pressure were within the normal range. She refused hemodialysis and then was hospitalized because of uremic encephalopathy. On admission, her serum potassium level was normal without treatment and plasma aldosterone concentration highly elevated. She received hemodialysis, and thereafter hypokalemia developed. We then administered spironolactone, whereupon serum potassium level returned to the normal range. In this case, we thought that normokalemia was balanced hypokalemia of primary aldosteronism with hyperkalemia of chronic renal failure, and that hypokalemia developed after hemodialysis was due to an imbalanced primary aldosteronism with end stage renal disease.