ABSTRACT
We describe 2 patients who suffered a pontine infarction and subsequently developed periodic leg movement (PLM). The temporal relationship between a stroke and subsequent PLM, as well as the absence of sleep-related disorders in patients' histories, favors the argument of a cause-and-effect relationship, with the observed association providing evidence for an anatomic substrate for PLM.
Subject(s)
Ischemic Attack, Transient/complications , Ischemic Attack, Transient/pathology , Nocturnal Myoclonus Syndrome/etiology , Pons/pathology , Female , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Nocturnal Myoclonus Syndrome/diagnosis , Severity of Illness Index , Videotape RecordingABSTRACT
We report a case of Wernicke's encephalopathy in which diffusion-weighted MR images demonstrated symmetrical hyperintense lesions in the paraventricular area of the third ventricles and medial thalami. Apparent diffusion coefficient mapping showed isointensity in the aforementioned areas. Diffusion-weighted MR images may provide evidence of vasogenic edema associated with thiamine deficiency, proven in the histopathology of experimental animals. In addition, diffusion-weighted MRI has many advantages over T2 or FLARE-weighted brain MRI in detecting structural and functional abnormalities in Wernicke's encephalopathy.
