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Fitoterapia ; 78(7-8): 577-9, 2007 Dec.
Article in English | MEDLINE | ID: mdl-17553632

ABSTRACT

Our previous study had demonstrated cytotoxicity of gallic acid on testicular cells with increasing the intracellular production of hydrogen peroxide. In the present study, the Panax ginseng root aqueous extract showed the cytoprotective effect on gallic acid-induced toxicity in TM3 mouse Leydig cells with decreasing the intracellular production of hydrogen peroxide.


Subject(s)
Panax , Phytotherapy , Plant Extracts/pharmacology , Protective Agents/pharmacology , Animals , Cells, Cultured , Dose-Response Relationship, Drug , Gallic Acid , Hydrogen Peroxide/metabolism , Leydig Cells/drug effects , Leydig Cells/metabolism , Male , Mice , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use , Plant Roots , Protective Agents/administration & dosage , Protective Agents/therapeutic use
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